You Searched For: ProSci Inc.

Catalog Number: (PRSI51-109)

Supplier: ProSci Inc.

Description: PMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including poly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate- specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region.

UOM: 1 * 250 µl

Sale

Catalog Number: (PRSIXP-5726-M)

Supplier: ProSci Inc.

Description: Anti-TNFSF10 Mouse Monoclonal Antibody [clone: 1.1_1A7-2B7]

UOM: 1 * 500 µG

Sale

Catalog Number: (PRSIXP-5724-M)

Supplier: ProSci Inc.

Description: Anti-TNFSF11 Mouse Monoclonal Antibody [clone: 2.1_3C12-2D11]

UOM: 1 * 500 µG

Sale

Catalog Number: (PRSI48-392)

Supplier: ProSci Inc.

Description: Integrins are a major class of cell adhesion molecules that mediate cell matrix interactions. They are composed of an alpha and a beta subunit. Beta 1 heterodimers are widely expressed and control various developmental processes, including neurogenesis, chondrogenesis, myoblast fusion, and skin and hair follicle morphogenesis.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSIXP-5272)

Supplier: ProSci Inc.

Description: Anti-TNFSF11 Rabbit Polyclonal Antibody

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSIXP-5273BT)

Supplier: ProSci Inc.

Description: Anti-TNFSF11 Rabbit Polyclonal Antibody (Biotin) [clone: ]

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI25-923)

Supplier: ProSci Inc.

Description: SLC2A13 is an H (+)-myo-inositol cotransporter. It can also transport related stereoisomers.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI25-911)

Supplier: ProSci Inc.

Description: SLCO1C1 is a member of the organic anion transporter family. SLCO1C1 is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI25-905)

Supplier: ProSci Inc.

Description: SLC27A4 is involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. It appears to be the principal fatty acid transporter in small intestinal enterocytes. SLC27A4 plays a role in the formation of the epidermal barrier. It is required for fat absorption in early embryogenesis. SLC27A4 has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI25-917)

Supplier: ProSci Inc.

Description: SLC15A2 belongs to the PTR2/POT transporter (TC 2.A.17) family. It is a multi-pass membrane protein. The expression/activity of PEPT2 (SLC15A2) may be a critical factor in the modulation of opioidergic neurotransmission in vivo.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI2019P)

Supplier: ProSci Inc.

Description: DR5 peptide is used for blocking the activity of DR5 antibody.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI4373)

Supplier: ProSci Inc.

Description: TOCA-1 Antibody: Actin reorganization is important for the regulation of neuronal morphology. A protein involved in this process, the transducer of cdc42-dependent actin assembly 1 (TOCA-1) protein, a member of the evolutionarily conserved pombe CDC15 homology (PCH) protein family, is an essential component of the Cdc42 pathway. TOCA-1 binds both N-WASP and Cdc42 and is essential for Cdc42- and PIP2-induced actin polymerization, suggesting that TOCA-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex. Decreased expression of TOCA-1 significantly enhances neurite elongation in PC-12 cells; its overexpression in the same cells suppresses neurite elongation. It has been suggested that TOCA-1 negatively regulates axon branching by regulating membrane trafficking by regulating membrane trafficking through the F-BAR/EFC domain. Multiple isoforms of TOCA-1 are known to exist.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI4387)

Supplier: ProSci Inc.

Description: Grik2 Antibody: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik2, also known as glutamate receptor 6, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Recent reports have suggested that defects in the Grik2 protein may be associated with autosomal recessive mental retardation and possibly other neurological disorders such as schizophrenia. Numerous isoforms of Grik2 are known to exist and may be subject to RNA editing within the second transmembrane domain, which is thought to alter the properties of ion flow. This Grik2 antibody may exhibit some cross-reactivity to Grik3.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI4377)

Supplier: ProSci Inc.

Description: Nhe-1 Antibody: The Na+/H+ antiporter (Nhe-1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells and is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, and tumor promoters. Nhe-1 acts as an anchor for actin filaments to control the integrity of the cortical cytoskeleton. This occurs through a previously unrecognized structural link between Nhe-1 and the actin-binding proteins ezrin, radixin, and moesin, collectively referred to as ERM proteins. A structural role for Nhe-1 has been proposed in regulating the cortical cytoskeleton that is independent of its function as an ion exchanger. It is also thought that Nhe-1 play a role in hypertension. At least two isoforms of Nhe-1 are known to exist.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI4391)

Supplier: ProSci Inc.

Description: Grik4 Antibody: Grik4 codes for the KA1 subunit of kainate-type ionotropic glutamate receptors which are critical regulators of network activity that act by modifying neuronal excitability, directly and indirectly, through GABAergic interneurons. Five subunits can assemble to form kainate receptors (KARs): GluR5 (coded by Grik1), GluR6 (coded by Grik2), and GluR7 (coded by Grik3) are the low-affinity subunits, and KA1 and KA2 are the high-affinity subunits. In the adult brain, KARs are located pre- and postsynaptically on pyramidal cells and on interneurons. Kainate receptors on GABA-containing interneurons enhance GABA release and thereby downregulate glutamatergic signaling. KARs have been implicated in numerous psychiatric disorders. Case control studies show significant association of Grik4 with both schizophrenia and bipolar disorder.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI25-960)

Supplier: ProSci Inc.

Description: MCTP1 belongs to the MCTP family.It contains 3 C2 domains. MCTP1 is a multi-pass membrane protein. It binds calcium via the C2 domains in absence of phospholipids. The function of MCTP1 remains unknown.

UOM: 1 * 50 µG

Sale