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Catalog Number: (90082.)

Supplier: Biotium

Description: Anhydrous DMSO (dimethyl sulfoxide; methyl sulfoxide) is recommended for preparing stock solutions.

UOM: 1 * 10 mL

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Catalog Number: (22023.)

Supplier: Biotium

Description: Paraformaldehyde, 4% in PBS is a ready-to-use fixation solution for cells or tissues.

UOM: 1 * 100 mL

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Supplier: Biotium

Description: MTT, XTT, and resazurin are reduced by mitochondrial metabolic activity to yield coloured or fluorescent products, and thus are useful for and assaying cell viability and quantitating cell number. MTT and XTT are reduced to coloured formazin salts that can be measured by absorbance. MTT generates an insoluble formazin salt, requiring cell lysis before the absorbance can be measured, while XTT does not require cell lysis for measurement. Resazurin is a non-fluorescent blue dye that is reduced to the pink fluorescent compound resorufin, which can be measured by fluorescence or absorbance.

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Catalog Number: (23007.)

Supplier: Biotium

Description: TrueBlack™ is a reagent for quenching lipofuscin autofluorescence in tissue sections for immunofluorescence staining. Lipofuscin consists of highly autofluorescent granules of oxidized proteins and lipids that build up in the lysosomes of aging cells. Lipofuscin granules fluoresce brightly in all channels used for fluorescence microscopy and accumulate in a cell and tissue types with age.

UOM: 1 * 1 mL

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Catalog Number: (40019.)

Supplier: Biotium

Description: PMA (propidium monoazide) dye is a DNA modifier invented by scientists at Biotium. It is a photo-reactive dye that binds to dsDNA with high affinity. Upon photolysis with visible light, PMA dye covalently attaches itself to dsDNA.

UOM: 1 * 100 µl

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Supplier: Biotium

Description: Highly cross-adsorbed rabbit anti-rat IgG (H L) secondary antibody labeled with our superior CF® Dyes.

Supplier: Biotium

Description: Cytotoxic agent that binds and inhibits dihydrofolate reductase. Useful for studying antimetabolite resistance, spontaneous gene amplification, and drug binding. Available conjugated to fluorescein and CF® Dyes.

Supplier: Biotium

Description: This is a goat anti-pig IgG (H+L) secondary antibody labeled with our superior CF® dyes.

Catalog Number: (30127.)

Supplier: Biotium

Description: The ExoBrite™ EV Surface Stain Sampler Kit, Green was developed to offer each of Biotium’s ExoBrite™ EV Surface Stains (CTB, WGA, and Annexin V) for assessing which stain offers the best coverage for the EV samples of interest.

UOM: 1 * 1 Each

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Supplier: Biotium

Description: Llama anti-rabbit IgG (H L) secondary antibody labeled with our superior CF® Dyes.

Supplier: Biotium

Description: This is a goat anti-rabbit IgG (H L) F(ab’)2 fragment secondary antibody labeled with superior CF® Dyes and other labels.

Catalog Number: (20885-100UL)

Supplier: Biotium

Description: Goat anti-alpaca IgG antibody that recognizes the VHH domain of heavy chain alpaca IgG. Labeled with CF® Dyes and suitable for western or IF applications.

UOM: 1 * 1 Each

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Catalog Number: (31084.)

Supplier: Biotium

Description: Ready to use DNA ladders are supplied in 1X loading buffer at an optimal concentration for loading GelRed™ and GelGreen™ precast gels.

UOM: 1 * 1 items

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Supplier: Biotium

Description: ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.

Supplier: Biotium

Description: BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFkB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.

Supplier: Biotium

Description: Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.