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Product Image-STMC78146.1

Human Recombinant IL-3, ACF

Supplier: STEMCELL Technologies
Description: Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes (Yang <i>et al.</i>; Dorssers <i>et al.</i>; Broughton <i>et al.</i>). IL-3 is produced by activated T cells and has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators such as histamine, IL-4, and IL-6 by basophils and eosinophils (Broughton <i>et al.</i>). The IL-3 receptor consists of a unique alpha subunit (CD123) and a beta common subunit (βc or CD131) that is shared with the receptors for IL-5 and GM-CSF, and is the principal signal transduction subunit for these cytokines. IL-3 binding to the heterodimeric receptor activates JAK/STAT, MAPK, and PI3K signaling pathways (Woodcock <i>et al.</i>). This product is animal component-free.

Product Image-STMC75006.1

GloCell™ Fixable Viability Dye Red 710

Supplier: STEMCELL Technologies
Description: Amine-labelling fluorescent dye for live/dead staining of mammalian cells - 100 tests.

Product Image-STMC100-0462

Anti-NK1.1 (CD161) Mouse Monoclonal Antibody [clone: PK136] (Biotin)

Supplier: STEMCELL Technologies
Description: (C3H x BALB/c) F1 hybrid monoclonal IgG2a antibody against mouse NK1.1 (CD161).

Product Image-STMC78045.3

Human Recombinant IL-4

Supplier: STEMCELL Technologies
Description: Human Interleukin 4 (IL-4) is important for immune responses to helminth infection as well as in allergic responses (Olpihant <i>et al.</i>). The IL-4 receptor consists of a heterodimer of IL-4Ra and common gamma chain. IL-4 receptor engagement leads to the activation of JAK1/3 and the recruitment of STAT6 and IRS1/2 (Nelms <i>et al.</i>). IL-4 drives immunoglobulin class switching in B cells (to IgE, IgG4), mast cell hyperplasia, mucus production, and the differentiation of naïve T cells into Th2 cells, which produce IL-4, IL-5, IL-10, and IL-13 (Bao <i>et al.</i>; Nelms <i>et al.</i>; Olpihant <i>et al.</i>). In addition to Th2 cells, IL-4 is produced by CD4+ NK T cells, γ/δ T cells, activated basophils, eosinophils, and mast cells. Human IL-4 does not cross-react with mouse cells (Park <i>et al.</i>).

Product Image-STMC02694

StemSpan™ Myeloid Expansion Supplement II (100X)

Catalog Number: (STMC02694)
Supplier: STEMCELL Technologies
Description: Serum-free culture supplement for expansion and differentiation of human monocytes.
UOM: 1 * 1 mL

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-SIELC-32.100.0310

HPLC Columns, Primesep C

Catalog Number: (SIELC-32.100.0310)
Supplier: SIELC Technologies
Description: Primesep C is a reverse-phase analytical column with embedded complex-forming groups.
UOM: 1 * 1 items

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Image Unavailable-BWRLBS3024

Anti-CYP7B1 Rabbit Polyclonal Antibody [clone: Q127]

Catalog Number: (BWRLBS3024)
Supplier: Bioworld Technology
Description: Synthetic peptide, corresponding to amino acids 101-150 of Human CYP7B1.
UOM: 1 * 100 µG
Product Image-STMC100-0031

EasySep™ Release Human APC Positive Selection Kit

Catalog Number: (STMC100-0031)
Supplier: STEMCELL Technologies
Description: Immunomagnetic positive selection of particle-free human cells labeled with APC-conjugated antibodies.
UOM: 1 * 1 KIT

Market Source Item This is a MarketSource item. Additional charges may apply

Product Image-STMC100-0109

EasySep™ Release Human CD45 Positive Selection Kits

Supplier: STEMCELL Technologies
Description: Immunomagnetic positive selection of particle-free CD45+ leukocytes from primary human tissues and tumors.

Product Image-STMC07521

Human Pluripotent Stem Cell Naïve State qPCR Array

Catalog Number: (STMC07521)
Supplier: STEMCELL Technologies
Description: For characterisation of gene expression associated with hPSC naïve or primed states.
UOM: 1 * 1 KIT

Market Source Item This is a MarketSource item. Additional charges may apply

Product Image-STMC01992

Human IgA ELISA Antibody Pair Kit

Catalog Number: (STMC01992)
Supplier: STEMCELL Technologies
Description: For detection and measurement of human immunoglobulin A.
UOM: 1 * 1 KIT

Market Source Item This is a MarketSource item. Additional charges may apply

Product Image-STMC17875

EasySep™ HLA Chimerism BC CD56 Positive Selection Kits

Supplier: STEMCELL Technologies
Description: Column-free immunomagnetic positive selection of human CD56+ cells for HLA analysis

Product Image-STMC17884

EasySep™ HLA Chimerism Whole Blood Myeloid Positive Selection Kits

Supplier: STEMCELL Technologies
Description: Column-free immunomagnetic positive selection of human CD33+ and CD66b+ cells for HLA analysis.

Product Image-STMC17683

EasySep™ Biotin Positive Selection Kit II

Supplier: STEMCELL Technologies
Description: Immunomagnetic positive selection of any cells labeled with biotinylated antibodies.

Product Image-STMC100-0670

EBV (BZLF1) Peptide Pool

Catalog Number: (STMC100-0670)
Supplier: STEMCELL Technologies
Description: The EBV (BZLF1) peptide pool is a lyophilised mixture of 59 peptides from trans-activator protein BZLF1 of Epstein-Barr virus (EBV; strain B95-8). BZLF1 is a DNA-binding protein that acts as a switch from latent infection to lytic infection. The pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 245 on BZLF1.
UOM: 1 * 1 KIT

Market Source Item This is a MarketSource item. Additional charges may apply

Product Image-STMC100-0317

Anti-CD45Ra Mouse Monoclonal Antibody [clone: HI100] (APC-Cy7)

Supplier: STEMCELL Technologies
Description: Mouse monoclonal IgG2b, antibody against human, chimpanzee, CD45RA, PE-conjugated.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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