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Catalog Number: (BOSSBS-7759R)
Supplier: Bioss
Description: GGCX is a 758 amino acid multi-pass membrane protein. Localized to the membrane of the endoplasmic reticulum, GGCX functions to mediate the vitamin K-dependent carboxylation of glutamate residues on target proteins, thereby producing calcium binding gamma-carboxyglutamate (Gla) residues on these proteins and simultaneously converting vitamin K to vitamin K epoxide. GGCX exists as a monomer and, via its ability to modify glutamate residues, it accomplishes the post-translational changes that are necessary for the activity of all vitamin K-dependent proteins (such as blood coagulation and bone matrix proteins). Defects in the gene encoding GGCX are the cause of combined deficiency of vitamin K-dependent clotting factors 1 (VKCFD1) and PXE-like disorder with multiple coagulation factor deficiency, both of which are characterized by abnormal skin, blood or bone function.
UOM: 1 * 100 µl


Supplier: Apollo Scientific
Description: Pyridoxine hydrochloride ≥99.5%

Supplier: PanReac AppliChem
Description: Folic acid
Supplier: VWR Chemicals
Description: L(+)-Ascorbic acid, TECHNICAL
Supplier: Avantor
Description: L(+)-Ascorbic acid, BAKER, Laboratory Reagent, J.T.Baker®
Catalog Number: (REST35100)
Supplier: Restek
Description: The composition of fatty acids by GC mix 1 consists of 6 components, they are (C20:0) methyl arachidate 40%, (C12:0) methyl dodecanoate 5%, (C14:0) methyl myristate 5%, (C18:1 [cis9]) methyl oleate 20%, (C16:0) methyl palmitate 10% and (C18:0) methyl stearate 20%.
UOM: 1 * 1 items


Supplier: Thermo Fisher Scientific
Description: Nicotinamide 99%

SDS

Catalog Number: (BOSSBS-3900R-HRP)
Supplier: Bioss
Description: CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor.Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. First described in patients who had rickets at a young age despite a history of adequate vitamin D intake. The patients sera had low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D.
UOM: 1 * 100 µl


Catalog Number: (8.40092.0025)
Supplier: Merck
Description: L(-)-Carnitine ≥98.0% for synthesis pH 6.5 - 8.5 (50 g/l, H₂O), Sigma-Aldrich®
UOM: 1 * 25 g

SDS


Supplier: Thermo Fisher Scientific
Description: 4-Aminobenzoic acid 99%
Supplier: Abcam
Description: Anti-Vitamin B2 Rabbit Monoclonal Antibody [clone: EPR20853-141]

Catalog Number: (ACRO421031000)
Supplier: Thermo Fisher Scientific
Description: D-α-Tocopherol 97+%
UOM: 1 * 100 mg

SDS


Supplier: Thermo Fisher Scientific
Description: DL-α-Tocopherol acetate 97%
Catalog Number: (4407-04)
Supplier: MACRON AVANTOR BRAND
Description: Crystals.
UOM: 1 * 500 g

Supplier: Abcam
Description: Anti-Vitamin D Binding protein Rabbit Monoclonal Antibody [clone: EPR2922Y]

Supplier: Avantor
Description: L(+)-Ascorbic acid 99.0-100.5%, fine-granular USP, FCC 20 - 80 Mesh, J.T.Baker®
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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