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Product Image-PRSI4307

Anti-STEAP2 Rabbit Polyclonal Antibody

Description: STEAP2 Antibody: The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 3 and STEAP4), STEAP2 promotes both iron and copper reduction. STEAP2 expression in transfected cells also correlated with iron or copper uptake, suggesting that the STEAP family of proteins may function to stimulate iron and copper uptake. STEAP2 is widely expressed in many tissues in the plasma membrane, but is most highly expressed in prostate. At least three isoforms of STEAP2 are known to exist.
Catalog Number: PRSI4307
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-PRSI3881

Anti-TIP47 Rabbit Polyclonal Antibody

Description: TIP47 Antibody: Tail-interacting protein (TIP47) is a cytosolic protein essential for the transport of mannose-6-phosphate receptors (MPRs) from endosomes to the trans-Golgi compartments in cells. TIP47 is recruited from the cytoplasm to the late endosomal surface by the Ras-associated protein Rab9 GTPase, enabling it to bind more efficiently to MPR cytoplasmic domains. Recently, it was shown that TIP47 regulates the expression of Rab9, as expression of siRNA to TIP47 in transfected cells dramatically decreased the half-life of the Rab9 protein in addition to stabilizing the subcellular localization of Rab9. At least two isoforms of TIP47 are known to exist.
Catalog Number: PRSI3881
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-PRSI6545

Anti-SLC35D2 Rabbit Polyclonal Antibody

Description: SLC35D2 Antibody: The solute carrier family SLC35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The role of the ER-resident SLC family member SLC35D2 is to transport both UDP-glucuronic acid and UDP-N-acetylgalactosamine. Its overexpression in transfected cells modulated cell surface heparin sulfate expression, suggesting that SLC35D2 is involved in heparin sulfate synthesis. SLC35D2-overexpressing cells also showed increased constitutive and hypotonic stress-stimulated release of UDP-GlcNAc, suggesting that SLC35D2 may be involved in UDP-sugar release and cell signaling.
Catalog Number: PRSI6545
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-734-0323

Gelatin culture dishes, Corning® BioCoat™

Description: PS coated with porcine gelatin. Corning® BioCoat™ gelatin cellware provides an attachment and growth promoting substrate for the culture of a variety of cell types. Gelatin is commonly used in the culture of normal and transfected cell types, including vascular endothelial, muscle, embryonic stem (ES) and F9 teratocarcinoma cells.
Catalog Number: 734-0323
UOM: 1 * 40 items
Supplier: Corning

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Product Image-PRSI56-860

Anti-UNC13B Rabbit Polyclonal Antibody

Description: This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq].
Catalog Number: PRSI56-860
UOM: 1 * 400 µl
Supplier: ProSci Inc.
Product Image-PRSI4779

Anti-IL34 Rabbit Polyclonal Antibody

Description: IL-34 Antibody: Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages.
Catalog Number: PRSI4779
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-PRSI3883

Anti-TIP47 Rabbit Polyclonal Antibody

Description: TIP47 Antibody: Tail-interacting protein (TIP47) is a cytosolic protein essential for the transport of mannose-6-phosphate receptors (MPRs) from endosomes to the trans-Golgi compartments in cells. TIP47 is recruited from the cytoplasm to the late endosomal surface by the Ras-associated protein Rab9 GTPase, enabling it to bind more efficiently to MPR cytoplasmic domains. Recently, it was shown that TIP47 regulates the expression of Rab9, as expression of siRNA to TIP47 in transfected cells dramatically decreased the half-life of the Rab9 protein in addition to stabilizing the subcellular localization of Rab9. At least two isoforms of TIP47 are known to exist.
Catalog Number: PRSI3883
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-PRSI4781

Anti-IL34 Rabbit Polyclonal Antibody

Description: IL-34 Antibody: Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages.
Catalog Number: PRSI4781
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-191844W

Vanadomolybdate reagent

Description: Vanadomolybdate reagent
Catalog Number: 191844W
UOM: 1 * 1 L
Supplier: VWR Chemicals

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Product Image-PRSI3451

Anti-CASP4 Rabbit Polyclonal Antibody

Description: Caspase-4 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1 beta and IL-18. Caspase-4 was initially identified as a homologous protein to Caspase-1 and the C. elegans Ced-3 which could induce apoptosis in transfected cells. More recent studies have shown that it can be activated by ER stress and has been suggested to be involved in multiple neuronal pathologies such as Alzheimer's disease.
Catalog Number: PRSI3451
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-PRSI5685

Anti-TMEM184C Rabbit Polyclonal Antibody

Description: TMEM184C Antibody: Anaplastic thyroid cancer is one of the most lethal forms of cancer, but the precise carcinogenic mechanism has not been identified. TMEM184C, also known as TMEM34, was identified in a cDNA microarray analysis as being down-regulated in anaplastic thyroid cancers compared to normal thyroid tissues. TMEM184C protein expression was also lower in cell lines derived from these types of cancers compared to that of normal thyroid tissues or cell lines based on other types of thyroid cancers. Furthermore, transfection of TMEM34 into KTA2 cells led to the inhibition of cell growth, suggesting that TMEM184C might act as a tumor suppressor in anaplastic thyroid cancers.
Catalog Number: PRSI5685
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-92504.290

Selenium reagent mixture for the determination of nitrogen acc. to Wieninger

Description: Selenium reagent mixture for the determination of nitrogen acc. to Wieninger
Catalog Number: 92504.290
UOM: 1 * 1 kg
Supplier: VWR Chemicals

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Product Image-PRSI3453

Anti-CASP4 Rabbit Polyclonal Antibody

Description: Caspase-4 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1 beta and IL-18. Caspase-4 was initially identified as a homologous protein to Caspase-1 and the C. elegans Ced-3 which could induce apoptosis in transfected cells. More recent studies have shown that it can be activated by ER stress and has been suggested to be involved in multiple neuronal pathologies such as Alzheimer's disease.
Catalog Number: PRSI3453
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-PRSIPM-4847

Anti-LY96 Mouse Monoclonal Antibody [clone: 1A2E3 ]

Description: MD-2 Monoclonal Antibody: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
Catalog Number: PRSIPM-4847
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-PRSIPM-4845

Anti-LY96 Mouse Monoclonal Antibody [clone: 9F1B1 ]

Description: MD-2 Monoclonal Antibody: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
Catalog Number: PRSIPM-4845
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-PRSI5047

Anti-CDIP Rabbit Polyclonal Antibody

Description: CDIP Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death; loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.
Catalog Number: PRSI5047
UOM: 1 * 100 µG
Supplier: ProSci Inc.
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