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Image Unavailable-BOSSBS-4065R-A350

Anti-P2RX2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-4065R-A350)
Supplier: Bioss
Description: Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4065R-HRP

Anti-P2RX2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-4065R-HRP)
Supplier: Bioss
Description: Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
UOM: 1 * 100 µl

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Image Unavailable-BOSSBS-4065R-A750

Anti-ATP receptor Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-4065R-A750)
Supplier: Bioss
Description: Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
UOM: 1 * 100 µl
Image Unavailable-MMMA7100123139

3M™ PELTOR™ X1B Earmuffs Neckband

Catalog Number: (MMMA7100123139)
Supplier: 3M
Description: 3M™ PELTOR™ X1 earmuffs are our lightweight hearing protectors with comfortable, soft ear cushions. They feature an electrically insulated, twin headband that decreases heat build-up on top of the head, and offer noise reduction up to 27 dB.
UOM: 1 * 10 items
Image Unavailable-BOSSBS-11060R-CY5

Anti-OTOA Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-11060R-CY5)
Supplier: Bioss
Description: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11060R-A680

Anti-OTOA/DFNB22 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-11060R-A680)
Supplier: Bioss
Description: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.
UOM: 1 * 100 µl
Product Image-521-4174

Biosafe benchtop ultracentrifuge System, Optima™ Max-XP

Catalog Number: (521-4174)
Supplier: Beckman Coulter
Description: The Optima MAX-XP's convenient touch-screen control features easy-to-read displays for gauging real-time speed, time, and temperature. The customisable user interface allows personalisation of easy-to-identify icons for up to twelve individuals, as well as sound and volume options. Multiple language capability: Access to an array of languages increases the Optima MAX-XP's functionality, anywhere in the world. From French and Spanish to Japanese, simplified Chinese and more, the Optima MAX-XP's ability to work in multiple languages enhances its value for laboratories around the world.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-11264R-CY3

Anti-MYO6 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11264R-CY3)
Supplier: Bioss
Description: Myosin VI a molecular motor involved in intracellular vesicle and organelle transport, is the only Myosin motor that binds to the pointed end of Actin. This unique Myosin has only one light chain in the lever-arm domain and has highly irregular stepping with a wide range of step sizes, unlike that of other characterized Myosins. It associates with Clathrin-coated vesicles and disabled 2, indicating a role for Myosin VI in endocytosis. Mouse Myosin VI is expressed within the sensory hair cells of the cochlea. Human Myosin VI is mapped to the centromeric region of chromosome 6, a region that shows syntenic homology with the corresponding mouse chromosome 9 region, where the Snell’s Waltzer mutation is located. The behavioral effects of the mouse Snell’s Waltzer mutation are lack of responsiveness to sound, hyperactivity, head tossing and circling, due to the disorganization and fusing of stereocilia bundles within the inner ear. Defects of Myosin VI cause autosomal dominant nonsyndromic sensori-neural deafness in humans. Human Myosin VI is expressed in fetal cochlea and brain, as well as in adult brain.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11264R-CY5

Anti-MYO6 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-11264R-CY5)
Supplier: Bioss
Description: Myosin VI a molecular motor involved in intracellular vesicle and organelle transport, is the only Myosin motor that binds to the pointed end of Actin. This unique Myosin has only one light chain in the lever-arm domain and has highly irregular stepping with a wide range of step sizes, unlike that of other characterized Myosins. It associates with Clathrin-coated vesicles and disabled 2, indicating a role for Myosin VI in endocytosis. Mouse Myosin VI is expressed within the sensory hair cells of the cochlea. Human Myosin VI is mapped to the centromeric region of chromosome 6, a region that shows syntenic homology with the corresponding mouse chromosome 9 region, where the Snell’s Waltzer mutation is located. The behavioral effects of the mouse Snell’s Waltzer mutation are lack of responsiveness to sound, hyperactivity, head tossing and circling, due to the disorganization and fusing of stereocilia bundles within the inner ear. Defects of Myosin VI cause autosomal dominant nonsyndromic sensori-neural deafness in humans. Human Myosin VI is expressed in fetal cochlea and brain, as well as in adult brain.
UOM: 1 * 100 µl
Product Image-460-0353

VWR®, Dry Block Heater, Digital, with Heated Lid

Catalog Number: (460-0353)
Supplier: VWR Collection
Description: Multi-purpose, high wattage, constant temperature, VWR® digital block heater which is economical, versatile and compact. This digital model, with heated lid, provides reproducable results, exceptional temperature uniformity and is ideal for a wide range of applications. Temperature calibration mode allows the user to calibrate the unit to an external temperature device. In timed mode, an alarm will sound when the time reaches zero and the unit reaches the set point temperature.
UOM: 1 * 1 items

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Product Image-460-0352

VWR®, Block Heaters, Digital

Supplier: VWR Collection
Description: Multi-purpose, high wattage, constant temperature, VWR® digital block heaters are economical, versatile and compact. These digital models provide reproducable results, exceptional temperature uniformity, and are ideal for a wide range of applications. Temperature calibration mode allows the user to calibrate the unit to an external temperature device. In timed mode, an alarm will sound when the time reaches zero and the unit reaches set point temperature.

Environmentally Preferable

Image Unavailable-BOSSBS-11060R-CY3

Anti-OTOA Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11060R-CY3)
Supplier: Bioss
Description: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11060R-A488

Anti-OTOA Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-11060R-A488)
Supplier: Bioss
Description: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11060R-HRP

Anti-OTOA Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-11060R-HRP)
Supplier: Bioss
Description: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11060R-CY7

Anti-OTOA Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-11060R-CY7)
Supplier: Bioss
Description: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.
UOM: 1 * 100 µl
Product Image-MMMAH540AV

Earmuffs, Peltor™ Optime III™

Catalog Number: (MMMAH540AV)
Supplier: 3M
Description: The earmuffs are designed specifically for heavy noise and combine effective protection with the ultimate in comfort. The model H540AV with headband is in Hi-VIZ design for high visibility. The advantage like conversations and warning signals are still easy to understand. An acoustic connection between the capsule interior and the space between the shells also achieves optimal low-frequency insulation.
UOM: 1 * 1 items
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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