You Searched For: Repetitive+Pipettes

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Anti-LRRC32 Mouse Monoclonal Antibody [clone: GARP5] (FITC (Fluorescein Isothiocyanate))

Catalog Number: (PRSI77-019)

Supplier: ProSci Inc.

Description: The GARP5 monoclonal antibody specifically reacts with human Glycoprotein A Repetitions Predominant (GARP, also known as LRRC32 or Garpin) molecule, a 80 kDa transmembrane glycoprotein expressed on the cell surface. GARP is expressed in activated Treg cells, placenta, pancreas, liver, skeletal muscle, heart, lung, and kidney, and it acts as a receptor for latent TGF-beta, which down-regulates the Treg cells action.

UOM: 1 * 25 Tests

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VWR® Pipette Controller

Catalog Number: (612-7179)

Supplier: VWR Collection

Description: The VWR® pipette controller is a compact and portable device that features multiple user-selectable modes and speeds to perform a wide range of liquid handling applications. Each device is supplied with a 3-year warranty.

UOM: 1 * 1 items

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VWR® Pipette Rack

Catalog Number: (612-3848)

Supplier: VWR Collection

Description: Ideal for serological pipettes.

UOM: 1 * 3 items

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VWR®, LTS® Compatible Pipette Tips

Supplier: VWR Collection

Description: VWR® LTS® compatible pipette tips feature a flexible seal area and a positive stop resulting in a secure seal with light ejection force on LTS® compatible pipettors.

Anti-KCNB2 Rabbit Polyclonal Antibody

Catalog Number: (PRSIXPS-2027)

Supplier: ProSci Inc.

Description: Voltage-gated K+ channels are important determinants of neuronal membrane excitability, and differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK)channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety on non-neuronal cells types including pancreatic islets, alveolar cells and cardiac myocytes. Kv2.1 and Kv2.2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells.

UOM: 1 * 100 µl

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Anti-CDK7 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-0569R)

Supplier: Bioss

Description: Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. Cyclin-dependent kinases (CDKs) are activated by the binding to a cyclin and mediate the progression through the cell cycle. Each different complex controls a specific transition between 2 subsequent phases in the cell cycle. Required for both activation and complex formation of CDK1/cyclin-B during G2-M transition, and for activation of CDK2/cyclins during G1-S transition (but not complex formation). CDK7 is the catalytic subunit of the CDK-activating kinase (CAK) complex. Phosphorylates SPT5/SUPT5H, SF1/NR5A1, POLR2A, p53/TP53, CDK1, CDK2, CDK4, CDK6 and CDK11B/CDK11. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation, thus regulating cell cycle progression. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Phosphorylation of POLR2A in complex with DNA promotes transcription initiation by triggering dissociation from DNA. Its expression and activity are constant throughout the cell cycle. Upon DNA damage, triggers p53/TP53 activation by phosphorylation, but is inactivated in turn by p53/TP53; this feedback loop may lead to an arrest of the cell cycle and of the transcription, helping in cell recovery, or to apoptosis. Required for DNA-bound peptides-mediated transcription and cellular growth inhibition.

UOM: 1 * 100 µl

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