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Terephthalic acid-[ring-D₄] (97% D) for NMR spectroscopy, Sigma-Aldrich®

Catalog Number: (SIAL195553-1G)
Supplier: Merck
Description: Terephthalic acid-[ring-D₄] (97% D) for NMR spectroscopy, Sigma-Aldrich®
UOM: 1 * 1 g
Image Unavailable-ROTHAE59.1

Chloroform-[D₁] stabilised for NMR spectroscopy

Catalog Number: (ROTHAE59.1)
Supplier: Roth Carl
Description: Chloroform-[D₁] stabilised for NMR spectroscopy
UOM: 1 * 100 mL

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-ENZOADISPA601488D

Anti-CRP55 Mouse Monoclonal Antibody [clone: FMC 75]

Supplier: ENZO LIFE SCIENCES
Description: The multifunctional, multi -compartmental protein Calreticulin (Crt) functions as a soluble molecular chaperone of new or misfolded proteins, as well as a Ca2+-binding protein. Most abundant in the ER lumen, Crt expression also occurs in other membrane-bound organelles, the cell surface, and extracellularly. Also known as CRP-55, calregulin and HACBP (high affinity calcium-binding protein), Crt contains the ER-retrieval sequence, KDEL, and is the solub le paralog of the ER membrane protein Calnexin (Cnx). Crt's three domains include a 180 residue N-terminal domain, a proline-rich Pdomainresidues 189 -288) that binds Ca2+ with high affinity and shares homology with Cnx and calmegin, and a 110 residue C-terminal domain that binds Ca2+ with low affinity but high capacity. The P-domain may interact with the co-chaperone ERp57 (Grp58), a thiol reductase. The NMR structure of the P -domain consists of an extended hairpin that appears to form a curved protrusion from the Crt core domain. Both Crt and its membrane bound homolog CNX interact with proteins and glycoproteins possessing monoglucosylated N -glycans. The Crt/Cnx cycle promotes correct folding, inhibits aggregation of folding intermediates, blocks premature oligomerization, regulates ER degradation, and prevents incompletely folded glycoproteins from exiting to the Golgi complex. Crt also appears to function as an auto-antigen in systemic lupus erythematosus, rheumatoid arthritis, celiac disease, complete congenital heart block, and halothane hepatitis. A diversity of additional functions attributed to Crt includes adhesion, blood function, and cardiac and neuronal development gene expression.

New Product

Image Unavailable-34955-1L

Acetonitrile ≥99.9% (by GC), CHROMASOLV™ NMR for LC-NMR, Riedel-de Haën™

Catalog Number: (34955-1L)
Supplier: Honeywell Chemicals
Description: Acetonitrile ≥99.9% (by GC), CHROMASOLV™ NMR for LC-NMR, Riedel-de Haën™
UOM: 1 * 1 L

SDS Environmentally Preferable


Image Unavailable-SIAL494275-10G

Chloroform-[D₁] for NMR spectroscopy, Sigma-Aldrich®

Supplier: Merck
Description: Chloroform-[D₁] for NMR spectroscopy, Sigma-Aldrich®

Image Unavailable-SIAL151831-250G

Chloroform-[D₁] for NMR spectroscopy, Sigma-Aldrich®

Supplier: Merck
Description: Chloroform-[D₁] for NMR spectroscopy, Sigma-Aldrich®

Image Unavailable-PROONMIAD621

Organic reference standards, 16β-hydroxystanozolol (NMIA D621), Certified Reference Material (CRM)

Catalog Number: (PROONMIAD621)
Supplier: LGC Standards PROMOCHEM
Description: Purity estimate obtained by quantitative NMR against an internal standard of dimethyl sulphone is 84,6 ± 1,5% mass fraction, (95% coverage interval). Supporting evidence is provided by HPLC with UV detection, Karl Fischer analysis and theromogravimetric analysis.
UOM: 1 * 1 mg
Image Unavailable-FLUOD024H.100ML

Methanol-[D₄], dehydrated (max. 0.03% H₂O) (99.8% D) for NMR spectroscopy

Supplier: FLUOROCHEM
Description: Methanol-[D₄], dehydrated (max. 0.03% H₂O) (99.8% D) for NMR spectroscopy

Image Unavailable-ENZOADISPA602D

Anti-CRP55 Rabbit Polyclonal Antibody

Supplier: ENZO LIFE SCIENCES
Description: The multifunctional, multi-compartmental protein Calreticulin (Crt) functions as a soluble molecular chaperone of new or misfolded proteins as well as a Ca2+-binding protein. Most abundant in the ER lumen, Crt expression also occurs in other membrane-bound organelles, the cell surface, and extracellularly. Also known as CRP-55, calregulin and HACBP (high affinity calcium-binding protein), Crt contains the ER-retrieval sequence, KDEL, and is the soluble paralog of the ER membrane protein Calnexin (Cnx). Crts three domains include a 180 residue N-terminal domain, a proline-rich P-domain (residues 189-288) that binds Ca2+ with high affinity and shares homology with Cnx and calmegin, and a 110 residue C-terminal domain that binds Ca2+ with low affinity but high capacity. The P-domain may interact with the co-chaperone ERp57 (Grp58), a thiol reductase. The NMR structure of the P-domain consists of an extended hairpin that appears to form a curved protrusion from the Crt core domain. Both Crt and its membrane bound homolog CNX interact with proteins and glycoproteins possessing monoglucosylated N-glycans. The Crt/Cnx cycle promotes correct folding, inhibits aggregation of folding intermediates, blocks premature oligomerization, regulates ER degradation, and prevents incompletely folded glycoproteins from exiting to the Golgi complex. Crt also appears to function as an auto-antigen in systemic lupus erythematosus, rheumatoid arthritis, celiac disease, complete congenital heart block, and halothane hepatitis. A diversity of additional functions attributed to Crt includes adhesion, blood function, and cardiac and neuronal development gene expression.

New Product

Image Unavailable-FLUOD215B.KIT

Deuterium oxide (99.96% D) for NMR spectroscopy

Catalog Number: (FLUOD215B.KIT)
Supplier: FLUOROCHEM
Description: Deuterium oxide (99.96% D) for NMR spectroscopy
UOM: 1 * 1 KIT

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-SIAL176796-100G

Sulphuric acid-[D₂] 98% (99.5% D) (w/w) in D₂O for NMR spectroscopy, Sigma-Aldrich®

Supplier: Merck
Description: Sulphuric acid-[D₂] 98% (99.5% D) (w/w) in D₂O for NMR spectroscopy, Sigma-Aldrich®

Image Unavailable-71759-4

Ammonium chloride-[¹⁵N], Overnight Express™, Sigma-Aldrich®

Catalog Number: (71759-4)
Supplier: Merck Millipore (Novagen)
Description: Overnight Express™ Autoinduction NMR Medium, 5 L kit
UOM: 1 * 4 SET
Image Unavailable-SIAL431915-10ML

Chloroform-[D₁] stabilised for NMR spectroscopy, Sigma-Aldrich®

Supplier: Merck
Description: Chloroform-[D₁] stabilised for NMR spectroscopy, Sigma-Aldrich®

Product Image-PIER22106

EMCH.TFA (E-Maleimidocaproic acid hydrazine trifluoroacetic acid salt) ≥90% (by NMR), Pierce™

Catalog Number: (PIER22106)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce EMCH is a mid-length, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).
UOM: 1 * 50 mg
Image Unavailable-FLUOD0138.1

Pyridine-[D₅], dehydrated (max. 0.05% H₂O) (99.5% D) for NMR spectroscopy

Catalog Number: (FLUOD0138.1)
Supplier: FLUOROCHEM
Description: Pyridine-[D₅], dehydrated (max. 0.05% H₂O) (99.5% D) for NMR spectroscopy
UOM: 1 * 1 items

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-PROONMIAP1796

Organic reference standards, β-zearalenol (NMIA P1796)

Catalog Number: (PROONMIAP1796)
Supplier: LGC Standards PROMOCHEM
Description: The purity estimate by traditional analytical techniques was obtained by subtraction from 100% of total impurities by HPLC with UV detection, Karl Fischer analysis, thermogravimetric analysis and 1H NMR is 99,3 ± 1,3% mass fraction, (95% coverage interval). Supporting evidence is provided by elemental microanalysis.
UOM: 1 * 5 mg
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