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Product Image-M6399-01

Mag-Bind® HDQ blood and tissue DNA 96 Kit

Supplier: OMEGA BIO-TEK
Description: The Mag-Bind® Blood and Tissue DNA HDQ 96 Kit is designed for rapid and reliable isolation of high quality genomic DNA from 100 to 200 μl blood samples, buccal swabs, buffy coat and cultured cells. All heating steps that limit robotic applications have been removed to allow for faster processing. Mag-Bind® particles HDQ provide quick magnetic response time reducing overall processing time. Utilising paramagnetic particles provides high quality DNA that is suitable for direct use in most downstream applications, such as qPCR, PCR and Next Generation Sequencing. The Mag-Bind® HDQ Blood DNA and Tissue 96 Kit is compatible with many robotic liquid handlers and magnetic processors, including Thermo Scientific KingFisher® Flex.

SDS Certificates

Product Image-786-175

Protein desalting and buffer exchange columns, SpinOUT™

Supplier: G-Biosciences
Description: The SpinOUT™ GT-100, GT-600 and GT-1200 columns are versatile, spin format columns for the desalting and buffer exchange of protein solutions ranging from 5 µl through to 4 ml sample volumes. The SpinOUT™ columns are available in three MWCO sizes for >700, >6000 or >30 000 dalton proteins and are suitable for samples containing as little as 20 µg protein/ml.

Product Image-D3485-00

E.Z.N.A.® Plant & Fungal DNA Kit

Supplier: OMEGA BIO-TEK
Description: Isolate DNA from plant or fungal samples using spin columns.

SDS

Image Unavailable-BOSSBS-10030R-CY3

Anti-LEO1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-10030R-CY3)
Supplier: Bioss
Description: Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1; it promotes leukemogenesis through association with KMT2A/MLL1-rearranged oncoproteins, such as KMT2A/MLL1-MLLT3/AF9 and KMT2A/MLL1-MLLT1/ENL. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys-4' (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription. PAF1C is involved in mRNA 3' end formation probably through association with cleavage and poly(A) factors. In case of infection by influenza A strain H3N2, PAF1C associates with viral NS1 protein, thereby regulating gene transcription. Involved in polyadenylation of mRNA precursors. Connects PAF1C to Wnt signaling.
UOM: 1 * 100 µl
Product Image-MILFZTC04S008

Pipette tips for sample preparation, ZipTip®

Supplier: Merck
Description: ZipTip is a 10 µl pipette tip with a 0,6 or 0,2 µl bed of chromatography media fixed at its end with no dead volume. It is ideal for concentrating and purifying samples for sensitive downstream analyses.

Product Image-730-1546

Extracta Plus RNA kits

Supplier: Quantabio
Description: Rapid extraction and purification of high-quality total RNA from cultured cells or tissue.

Image Unavailable-PATH-ROTAVIR.A

qPCR detection kits for gastrointestinal infections, Genesig®

Supplier: PRIMERDESIGN
Description: PCR kits for the detection and simultaneous quantification of gastrointestinal pathogens.

Image Unavailable-91A-1KT

α-Naphthyl Acetate (Non-Specific Esterase) Kit Kit formulated with all liquid reagents., Sigma-Aldrich®

Catalog Number: (91A-1KT)
Supplier: SIGMA ALDRICH MICROSCOPY
Description: Esterases are ubiquitous in nature and encompass a series of different enzymes acting upon select substrates.
UOM: 1 * 1 KIT
Product Image-CAYM700420-96

Ascorbate Assay Kit

Catalog Number: (CAYM700420-96)
Supplier: Cayman Chemical
Description: A kit for measuring ascorbate.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-10030R-A555

Anti-LEO1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-10030R-A555)
Supplier: Bioss
Description: Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1; it promotes leukemogenesis through association with KMT2A/MLL1-rearranged oncoproteins, such as KMT2A/MLL1-MLLT3/AF9 and KMT2A/MLL1-MLLT1/ENL. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys-4' (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription. PAF1C is involved in mRNA 3' end formation probably through association with cleavage and poly(A) factors. In case of infection by influenza A strain H3N2, PAF1C associates with viral NS1 protein, thereby regulating gene transcription. Involved in polyadenylation of mRNA precursors. Connects PAF1C to Wnt signaling.
UOM: 1 * 100 µl
Image Unavailable-D4616-01

Food DNA kit, E.Z.N.A.®

Supplier: OMEGA BIO-TEK
Description: The E.Z.N.A.® Food DNA Kit allows rapid and reliable isolation of high quality DNA from complex matrixes such as processed food, chocolate, cereals and meat.

Certificates

Image Unavailable-CAYM500701-96

Creatinine (urinary) colorimetric assay kit

Supplier: Cayman Chemical
Description: For the measurement of creatinine levels in urine.

Product Image-391-1255

VWR®, Adhesive PCR Film Seals

Supplier: VWR Collection
Description: These heat resistant 74,9 µm thick films are designed for thermal cycling applications. Polypropylene films are not pierceable. For PCR applications, where piercing with pipette tips or robotic probes is required for product recovery, use aluminium foil films. For real-time PCR applications, where maximum optical clarity is required, use optically-clear polyester films.

Product Image-PRSI56-905

Anti-PAPOLG Rabbit Polyclonal Antibody

Catalog Number: (PRSI56-905)
Supplier: ProSci Inc.
Description: This gene encodes a member of the poly(A) polymerase family which catalyzes template-independent extension of the 3' end of a DNA/RNA strand. This enzyme shares 60% identity to the well characterized poly(A) polymerase II (PAPII) at the amino acid level. These two enzymes have similar organization of structural and functional domains. This enzyme is exclusively localized in the nucleus and exhibits both nonspecific and CPSF (cleavage and polyadenylation specificity factor)/AAUAAA-dependent polyadenylation activity. This gene is located on chromosome 2 in contrast to the PAPII gene, which is located on chromosome 14.
UOM: 1 * 400 µl

New Product


Product Image-MILFLSKNS0500

Reagents for Montage® Plasmid Miniprep 96 Kits

Supplier: Merck
Description: Nucleic Acid Purification Kits and Reagents, RNase A, 0,9 ml

Image Unavailable-PRSI91-123

Human recombinant Flap Endonuclease 1 (from E. coli)

Catalog Number: (PRSI91-123)
Supplier: ProSci Inc.
Description: Flap Endonuclease 1 (FEN1) is a member of the XPG/RAD2 endonuclease family. During DNA replication, FEN1 cleaves the 5'-overhanging flap structure and processes the 5' ends of Okazaki fragments for synthesis. FEN1 also exhibits RNase H activity by possessing 5'-3' exonuclease activity on gapped double-stranded or nicked DNA, FEN1 is involved in the long patch base excision repair (LP-BER) pathway, it can cleave within the apurinic/apyrimidinic (AP) site-terminated flap. FEN1 can prevent flaps from equilibrating into structures that lead to duplications and deletions. FEN1 is also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
UOM: 1 * 50 µG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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