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Image Unavailable-BOSSBS-8874R-CY5.5

Anti-GPBAR1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-8874R-CY5.5)
Supplier: Bioss
Description: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8874R

Anti-GPBAR1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-8874R)
Supplier: Bioss
Description: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
UOM: 1 * 100 µl
Product Image-ACRO424560010

2,2,4-Trimethylpentane 99+% ACS

Supplier: Thermo Fisher Scientific
Description: 2,2,4-Trimethylpentane 99+% ACS

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Image Unavailable-BOSSBS-11892R-CY7

Anti-NAV2/RAINB1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-11892R-CY7)
Supplier: Bioss
Description: Neuron navigator 2 (NAV2), also known as RAINB1 (retinoic acid inducible in neuroblastoma 1), POMFIL2 (pore membrane and/or filament-interacting-like protein 2), HELAD1 (helicase APC down-regulated 1), unc53H2 or steerin-2, is a 2,488 amino acid nuclear protein that plays a role in the development of sensory organs. Existing as thirteen alternatively spliced isoforms, Neuron navigator 2 displays 3' to 5' helicase activity and exonuclease activity and participates in the catalysis of ATP to ADP. Neuron navigator 2 is highly expressed in the nervous system of developing embryos and colon carcinomas, as well as in liver, brain and kidney. Lower levels of expression are found in lung, thyroid, spinal cord, heart, placenta and mammary gland. Neuron navigator 2 belongs to the Nav/unc-53 family and contains one CH (calponin-homology) domain.
UOM: 1 * 100 µl
Product Image-20119.368

Acetic acid 80% ≥80%, TECHNICAL

Catalog Number: (20119.368)
Supplier: VWR Chemicals
Description: Acetic acid 80% ≥80%, TECHNICAL
UOM: 1 * 5 L

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Product Image-6516.2500

Acetic acid 30% for biopharmaceutical production

Catalog Number: (6516.2500)
Supplier: VWR Chemicals
Description: Acetic acid 30% for biopharmaceutical production
UOM: 1 * 2,5 L

SDS Certificates


Image Unavailable-HONC65722-2.5L

2,2,4-Trimethylpentane, liquid, Burdick & Jackson™

Catalog Number: (HONC65722-2.5L)
Supplier: Honeywell Chemicals
Description: 2,2,4-Trimethylpentane, liquid, Burdick & Jackson™
UOM: 1 * 2,5 L
Image Unavailable-BOSSBS-11621R-A555

Anti-GUCA2A Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-11621R-A555)
Supplier: Bioss
Description: The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10kDa form is found circulating in the blood.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11621R-A680

Anti-Guanylin Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-11621R-A680)
Supplier: Bioss
Description: The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase Signalling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10 kDa form is found circulating in the blood.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6110R-HRP

Anti-SPARCL1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-6110R-HRP)
Supplier: Bioss
Description: SPARC (secreted protein acidic and rich in cysteine) is a phosphorylated, acidic, glycine-rich glycoprotein that is secreted by endothelial cells and is present in large amounts in the parietal endoderm of mouse embryos and in human placenta. SPARC-like protein 1 (SPARCL1), also known as high endothelial venule protein (Hevin) or MAST9, is a 664 amino acid member of the SPARC family of proteins. Highly expressed in lymph node, heart, lung, brain, skeletal muscle, ovary, colon and small intestine, SPARCL1 is a secreted protein that contains one EF-hand domain, one follistatin-like domain and one Kazal-like domain. SPARCL1 is implicated to play a role in neuronal remodeling and tumor suppression. The gene encoding SPARCL1 maps to chromosome 4q22.1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6110R-A350

Anti-SPARCL1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-6110R-A350)
Supplier: Bioss
Description: SPARC (secreted protein acidic and rich in cysteine) is a phosphorylated, acidic, glycine-rich glycoprotein that is secreted by endothelial cells and is present in large amounts in the parietal endoderm of mouse embryos and in human placenta. SPARC-like protein 1 (SPARCL1), also known as high endothelial venule protein (Hevin) or MAST9, is a 664 amino acid member of the SPARC family of proteins. Highly expressed in lymph node, heart, lung, brain, skeletal muscle, ovary, colon and small intestine, SPARCL1 is a secreted protein that contains one EF-hand domain, one follistatin-like domain and one Kazal-like domain. SPARCL1 is implicated to play a role in neuronal remodeling and tumor suppression. The gene encoding SPARCL1 maps to chromosome 4q22.1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6110R-A647

Anti-SPARCL1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-6110R-A647)
Supplier: Bioss
Description: SPARC (secreted protein acidic and rich in cysteine) is a phosphorylated, acidic, glycine-rich glycoprotein that is secreted by endothelial cells and is present in large amounts in the parietal endoderm of mouse embryos and in human placenta. SPARC-like protein 1 (SPARCL1), also known as high endothelial venule protein (Hevin) or MAST9, is a 664 amino acid member of the SPARC family of proteins. Highly expressed in lymph node, heart, lung, brain, skeletal muscle, ovary, colon and small intestine, SPARCL1 is a secreted protein that contains one EF-hand domain, one follistatin-like domain and one Kazal-like domain. SPARCL1 is implicated to play a role in neuronal remodeling and tumor suppression. The gene encoding SPARCL1 maps to chromosome 4q22.1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6110R-CY7

Anti-SPARCL1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-6110R-CY7)
Supplier: Bioss
Description: SPARC (secreted protein acidic and rich in cysteine) is a phosphorylated, acidic, glycine-rich glycoprotein that is secreted by endothelial cells and is present in large amounts in the parietal endoderm of mouse embryos and in human placenta. SPARC-like protein 1 (SPARCL1), also known as high endothelial venule protein (Hevin) or MAST9, is a 664 amino acid member of the SPARC family of proteins. Highly expressed in lymph node, heart, lung, brain, skeletal muscle, ovary, colon and small intestine, SPARCL1 is a secreted protein that contains one EF-hand domain, one follistatin-like domain and one Kazal-like domain. SPARCL1 is implicated to play a role in neuronal remodeling and tumor suppression. The gene encoding SPARCL1 maps to chromosome 4q22.1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6110R-FITC

Anti-SPARCL1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-6110R-FITC)
Supplier: Bioss
Description: SPARC (secreted protein acidic and rich in cysteine) is a phosphorylated, acidic, glycine-rich glycoprotein that is secreted by endothelial cells and is present in large amounts in the parietal endoderm of mouse embryos and in human placenta. SPARC-like protein 1 (SPARCL1), also known as high endothelial venule protein (Hevin) or MAST9, is a 664 amino acid member of the SPARC family of proteins. Highly expressed in lymph node, heart, lung, brain, skeletal muscle, ovary, colon and small intestine, SPARCL1 is a secreted protein that contains one EF-hand domain, one follistatin-like domain and one Kazal-like domain. SPARCL1 is implicated to play a role in neuronal remodeling and tumor suppression. The gene encoding SPARCL1 maps to chromosome 4q22.1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11621R-A750

Anti-Guanylin Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-11621R-A750)
Supplier: Bioss
Description: The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase Signalling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10 kDa form is found circulating in the blood.
UOM: 1 * 100 µl
Product Image-20109.364

Acetic acid 90% ≥90%, GPR RECTAPUR®

Supplier: VWR Chemicals
Description: Acetic acid 90% ≥90%, GPR RECTAPUR®

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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