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You Searched For: 2-Chloro-5-fluoropyrimidine


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Image Unavailable-INVVSUD-5FU

5-Fluorouracil

Catalog Number: (INVVSUD-5FU)
Supplier: Invivogen
Description: 5-Fluorouracil
UOM: 1 * 250 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-SIAL47190-1G-F

5-Fluoroorotic acid hydrate, Sigma-Aldrich®

Supplier: Merck
Description: 5-Fluoroorotic acid hydrate, Sigma-Aldrich®

Image Unavailable-468740010.

5'-Deoxy-5-fluorocytidine 95%

Supplier: Thermo Fisher Scientific
Description: 5'-Deoxy-5-fluorocytidine 95%

New Product

Image Unavailable-SIALF5013-250MG

5-Fluoroorotic acid hydrate, Sigma-Aldrich®

Supplier: Merck
Description: 5-Fluoroorotic acid hydrate, Sigma-Aldrich®

Image Unavailable-FLUOM02721-5G

5-Fluoroorotic acid

Catalog Number: (FLUOM02721-5G)
Supplier: FLUOROCHEM
Description: 5-Fluoroorotic acid
UOM: 1 * 5 g

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-ICNA0210172205

5-Fluorouracil ∼99%, powder

Supplier: MP Biomedicals
Description: 5-Fluorouracil (5-FU) inhibits the activity of thymidylate synthetase, which affects pyrimidine synthesis and leads to depletion of intracellular TTP pools.

Image Unavailable-MOLE10130089-25MG

5-Fluoro-5'-deoxyuridine (Doxifluridine)

Catalog Number: (MOLE10130089-25MG)
Supplier: Molekula
Description: 5-Fluoro-5'-deoxyuridine (Doxifluridine)
UOM: 1 * 25 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-MOLE59821456-100MG

5-Fluoroorotic acid

Catalog Number: (MOLE59821456-100MG)
Supplier: Molekula
Description: 5-Fluoroorotic acid
UOM: 1 * 100 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-SERA21650.02

5-Fluoroorotic acid

Catalog Number: (SERA21650.02)
Supplier: Serva
Description: 5-Fluoroorotic acid
UOM: 1 * 250 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-ROTH4015.3

5-Fluoroorotic acid

Catalog Number: (ROTH4015.3)
Supplier: Roth Carl
Description: 5-Fluoroorotic acid
UOM: 1 * 2,5 g

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-SIALF8791-100MG

5-Fluoro-5'-deoxyuridine (Doxifluridine), Sigma-Aldrich®

Supplier: Merck
Description: 5-Fluoro-5'-deoxyuridine (Doxifluridine), Sigma-Aldrich®

Product Image-R0812

5-Fluoroorotic acid enzyme substrate

Supplier: Thermo Fisher Scientific
Description: Thermo Scientific 5-Fluoroorotic Acid (5-fluorouracil-6-carboxylic acid monohydrate; 5-FOA) is used in yeast molecular genetics to detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) dicarboxylase

Image Unavailable-PRSI34-176

Anti-TYMS Mouse Monoclonal Antibody [clone: SPM453]

Catalog Number: (PRSI34-176)
Supplier: ProSci Inc.
Description: It recognises a protein of 36 kDa, identified as Thymidylate Synthase (TS). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
UOM: 1 * 100 µG

New Product


Image Unavailable-PRSI33-918

Anti-TYMS Mouse Monoclonal Antibody [clone: TYSY9]

Catalog Number: (PRSI33-918)
Supplier: ProSci Inc.
Description: Thymidylate synthase converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. Thymidylate synthase is also a critical target for the fluoropyrimidines, an important group of anti-neoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates thymidylate synthase by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of thymidylate synthase protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
UOM: 1 * 100 µG

New Product


Image Unavailable-ICNA0215421091

5-Fluoroorotic acid ≥98%, pale yellow crystalline powder

Supplier: MP Biomedicals
Description: FOA is a derivative of a pyrimidine precursor and is selectively toxic to yeast cells which synthesize orotidine-5’-phosphate decarboxylase. FOA has been used in a positive selection for uracil-requiring mutants(in the presence of large numbers of wild-type cells) lacking OMPdecase or OPRTase activities. This results in efficient strains for effective transformation systems.

Image Unavailable-PRSI33-219

Anti-TYMS Mouse Monoclonal Antibody [clone: TMS715]

Catalog Number: (PRSI33-219)
Supplier: ProSci Inc.
Description: This antibody is specific for a protein of 36 kDa, identified as Thymidylate Synthase (TS). Thymidylate synthase converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. Thymidylate synthase is also a critical target for the fluoropyrimidines, an important group of anti-neoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates thymidylate synthase by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of thymidylate synthase protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
UOM: 1 * 100 µG

New Product


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
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Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
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