Anti-CD3 Mouse Monoclonal Antibody [clone: SK7] (FITC)

Supplier: STEMCELL Technologies
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60127FI 60127FI.1
STMC60127FIEA 212 GBP
STMC60127FI STMC60127FI.1
Anti-CD3 Mouse Monoclonal Antibody [clone: SK7] (FITC)
Antibodies
Mouse monoclonal IgG1 antibody against human, chimpanzee CD3, FITC-conjugated.

  • T cells

This monoclonal antibody reacts with the ~20 kDa cluster of differentiation 3 epsilon (CD3ε) subunit of human T cell receptor (TCR)/CD3 complex, which is expressed on the surface of ~95% of mature T cells and natural killer T cells, and variably on thymocytes. A majority of T cell neoplasms also express CD3. The CD3 complex consists of subunits γ, δ, ε, η, and ζ and binds noncovalently with the TCR. It is involved in transducing antigen recognition signals into the cytoplasm of T cells and in regulating expression of the TCR on cell surfaces. Activation of T cells by the TCR involves the cytoplasmic tails of the CD3 subunits, which are structurally related to type 1 transmembrane proteins and members of the immunoglobulin superfamily. Mutations in the CD3 subunits have been associated with various immunodeficiency disorders including severe combined immunodeficiency (SCID).

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: CD3
Clonality: Monoclonal
Clone: SK7
Conjugation: FITC
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Chimpanzee;Human
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