Anti-E-cadherin (CD324) Rat Monoclonal Antibody [clone: DECMA-1]

Supplier: STEMCELL Technologies
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60157 60157.1
STMC60157EA 306 GBP
STMC60157 STMC60157.1
Anti-E-cadherin (CD324) Rat Monoclonal Antibody [clone: DECMA-1]
Antibodies
Rat monoclonal IgG1 antibody against human, mouse, dog E-cadherin (CD324), unconjugated.

  • Airway cells

The DECMA-1 antibody recognizes E-cadherin, a calcium-dependent transmembrane glycoprotein involved in cell-cell adhesion, bacterial pathogenesis, and tumor invasion. The extracellular region of E-cadherin is composed of multiple cadherin repeats that contain calcium-binding motifs. The cytoplasmic domain of E-cadherin is reported to interact with a range of intracellular proteins including erbin, ezrin, caspase-3, caspase-8, β-catenin, presenilin 1, and casein kinase II. E-cadherin is expressed in most epithelial cells and in erythroid cells. The E-cadherin antibody is often used as a neutralizing antibody to inhibit E-cadherin-mediated cell-cell interactions.

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: E-cadherin (CD324)
Clonality: Monoclonal
Clone: DECMA-1
Conjugation: Unconjugated
Epitope:
Host: Rat
Isotype: IgG1 kappa
Reactivity: Dog;Human;Mouse;Pig
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