Anti-TCR Gamma/Delta Hamster Monoclonal Antibody [clone: GL3] (FITC)

Supplier: STEMCELL Technologies
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Anti-TCR Gamma/Delta Hamster Monoclonal Antibody [clone: GL3] (FITC)
Antibodies
Hamster (Armenian) monoclonal IgG2 antibody against mouse T cell receptor gamma/delta, FITC-conjugated.

  • T cells
  • T cells Other Subsets

The GL3 antibody reacts with the δ chain of the murine T cell receptor γ/δ (TCRγ/δ or TCR gamma/delta), a subtype of the TCR involved in the recognition of both peptide and lipid antigens. TCRγ/δ comprises a heterodimer (~ 80 kDa in humans) of disulfide-linked γ and δ subunits that associates with CD3 on the cell surface. It is a member of the immunoglobulin superfamily. TCRγ/δ is expressed on a subpopulation of T cells in the circulation but may be found on up to 50% of the T cells in epithelial cell-rich tissues. These cells have roles in oral and tumor-associated tolerance as well as autoimmune disease and have been described as a link between the adaptive and innate immune responses. Once activated, they secrete effector cytokines in a subtype- and context-specific manner. Most γ/δ T cells are CD4-/CD8-, though some express CD8. The GL3 antibody recognizes an epitope in the constant region of the δ chain and can reportedly activate TCRγ/δ+ cells.

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type: Anti-TCR Gamma/Delta Hamster Monoclonal Antibody [clone: GL3] (FITC)
Antigen: TCR Gamma/Delta
Clonality: Monoclonal
Clone: GL3
Conjugation: FITC
Epitope:
Host: Hamster
Isotype: IgG2 kappa
Reactivity: Mouse
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