Salmonella typhimurium (strain LT2/SGSC1412/ATCC 700720) recombinant tryptophan synthase (from E. coli)

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92-668
PRSI92-668EA 829 GBP
PRSI92-668
Salmonella typhimurium (strain LT2/SGSC1412/ATCC 700720) recombinant tryptophan synthase (from E. coli)
Enzymes

Tryptophan synthase is a multienzyme alpha2 beta 2 complex composed of two protein subunit. Tryptophan synthase catalyses the last two steps in the synthesis of L-tryptophan (L-Trp). The alpha-subunit catalyses cleavage of 3-indole-d-glycerol 3′-phosphate (IGP) to give indole and D-glyceraldehyde 3′-phosphate (G3P). Indole is then transferred through a 25-Å hydrophobic tunnel to the beta -subunit. The beta 2 subunit contains pyridoxal 5'-phosphate and catalyses several pyridoxal 5'-phosphate-dependent reactions, including/3-elimination reactions 6 and a thiol-dependent transamination reaction. This enzyme is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from Animalia. As humans do not have tryptophan synthase, this enzyme has been explored as a potential drug target.


Fusion-Tag: N-6 His tag


This recombinant protein can be used for biological assays. For research use only.

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