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Catalog Number: (PRSI42-198)

Supplier: ProSci Inc.

Description: Anti-TET2 Goat Polyclonal Antibody

UOM: 1 * 100 µG

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Catalog Number: (PRSI42-190)

Supplier: ProSci Inc.

Description: Anti-TPCN2 Goat Polyclonal Antibody

UOM: 1 * 100 µG

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Catalog Number: (PRSI42-215)

Supplier: ProSci Inc.

Description: Anti-EML5 Goat Polyclonal Antibody

UOM: 1 * 100 µG

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Catalog Number: (PRSI27-062)

Supplier: ProSci Inc.

Description: The specific function of ARMC3 is not yet known.Armadillo/beta-catenin (CTNNB1; MIM 116806)-like (ARM) domains are imperfect 45-amino acid repeats involved in protein-protein interactions. ARM domain-containing proteins, such as ARMC3, function in signal transduction, development, cell adhesion and mobility, and tumor initiation and metastasis (Li et al., 2006 [PubMed 16915934]).

UOM: 1 * 50 µG

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Catalog Number: (PRSI42-829)

Supplier: ProSci Inc.

Description: Anti-PSMA4 Goat Polyclonal Antibody

UOM: 1 * 100 µG

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Catalog Number: (PRSI27-069)

Supplier: ProSci Inc.

Description: RASGEF1C is a guanine nucleotide exchange factor (GEF).

UOM: 1 * 50 µG

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Catalog Number: (PRSI27-068)

Supplier: ProSci Inc.

Description: COX18 is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. COX18 is essential for the activity and assembly of cytochrome c oxidase. COX18 plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).

UOM: 1 * 50 µG

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Catalog Number: (PRSI27-060)

Supplier: ProSci Inc.

Description: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. SPAG8 is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa.The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.

UOM: 1 * 50 µG

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Catalog Number: (PRSI27-091)

Supplier: ProSci Inc.

Description: SFRP2 is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UOM: 1 * 50 µG

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Catalog Number: (PRSI27-085)

Supplier: ProSci Inc.

Description: PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.

UOM: 1 * 50 µG

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Catalog Number: (PRSI27-665)

Supplier: ProSci Inc.

Description: IFN regulatory factor (IRF)-4 is a lymphoid/myeloid-restricted member of the IRF transcription factor family that plays an essential role in the homeostasis and function of mature lymphocytes. IRF-4 expression is tightly regulated in resting primary T cells and is transiently induced at the mRNA and protein levels after activation by Ag-mimetic stimuli such as TCR cross-linking or treatment with phorbol ester and calcium ionophore (PMA/ionomycin).

UOM: 1 * 100 µG

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Catalog Number: (PRSI27-667)

Supplier: ProSci Inc.

Description: PTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.

UOM: 1 * 100 µG

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Catalog Number: (PRSI27-666)

Supplier: ProSci Inc.

Description: The TSFM gene encodes a protein that is expressed in all tissues, with the highest levels of expression in skeletal muscle, liver, and kidney.

UOM: 1 * 50 µG

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Catalog Number: (PRSI42-856)

Supplier: ProSci Inc.

Description: Anti-VIPR1 Goat Polyclonal Antibody

UOM: 1 * 100 µG

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Catalog Number: (PRSI42-850)

Supplier: ProSci Inc.

Description: Anti-MKRN1 Goat Polyclonal Antibody

UOM: 1 * 100 µG

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Catalog Number: (PRSI46-102)

Supplier: ProSci Inc.

Description: Anti-ORC4 Goat Polyclonal Antibody

UOM: 1 * 100 µG

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