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L-165,041 is a potent and selective agonist of the nuclear receptor PPAR/ (Ki = 9 nM, EC50 = 500 nM for hPPAR/).{7166,10670} It is less effective against PPAR and PPAR, with activity at those receptors depending on cell type and system of stu 1 * 50 mg

Catalog Number: (CAYM9000249-50)

Supplier: Cayman Chemical

Description: L-165,041 is a potent and selective agonist of the nuclear receptor PPAR/ (Ki = 9 nM, EC50 = 500 nM for hPPAR/).{7166,10670} It is less effective against PPAR and PPAR, with activity at those receptors depending on cell type and system of stu 1 * 50 mg

UOM: 1 * 50 mg

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Rofecoxib is a non-steroidal anti-inflammatory drug that inhibits cyclooxygenase (COX)-2 activity with 1,000-fold selectivity over t hat of COX-1 (IC50s = 26 nM and > 50 µM in human osteosarcoma cells).{12018} In in vivo rodent models, rofecoxib can 1 * 100 mg

Catalog Number: (CAYM10010260-100)

Supplier: Cayman Chemical

Description: Rofecoxib is a non-steroidal anti-inflammatory drug that inhibits cyclooxygenase (COX)-2 activity with 1,000-fold selectivity over t hat of COX-1 (IC50s = 26 nM and > 50 µM in human osteosarcoma cells).{12018} In in vivo rodent models, rofecoxib can 1 * 100 mg

UOM: 1 * 100 mg

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SecinH3 is a selective inhibitor of cytohesins, blocking human, mouse, and Drosophila cytohesins with IC50 values of 2.4 to 5.6 µM.{ 14565} It binds the Sec7 domain of these small Arf-GEFs but does not bind Sec7 domains of larger Arf-GEFs.{25739} In 1 * 10 mg

Catalog Number: (CAYM10009570-10)

Supplier: Cayman Chemical

Description: SecinH3 is a selective inhibitor of cytohesins, blocking human, mouse, and Drosophila cytohesins with IC50 values of 2.4 to 5.6 µM.{ 14565} It binds the Sec7 domain of these small Arf-GEFs but does not bind Sec7 domains of larger Arf-GEFs.{25739} In 1 * 10 mg

UOM: 1 * 10 mg

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AdipoRon is an orally active small molecule AdipoR agonist that binds AdipoR1 and AdipoR2 with KD values of 1.8 and 3.1 µM, respecti vely.{25721} At 50 mg/kg, it acts similarly to adiponectin, activating AMPK and PPARα pathways and reducing insulin r 1 * 10 mg

Catalog Number: (CAYM15941-10)

Supplier: Cayman Chemical

Description: AdipoRon is an orally active small molecule AdipoR agonist that binds AdipoR1 and AdipoR2 with KD values of 1.8 and 3.1 µM, respecti vely.{25721} At 50 mg/kg, it acts similarly to adiponectin, activating AMPK and PPARα pathways and reducing insulin r 1 * 10 mg

UOM: 1 * 10 mg

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