You Searched For: Bioss

Catalog Number: (BOSSBS-3925R-CY3)

Supplier: Bioss

Description: This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity).

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Catalog Number: (BOSSBS-3925R-CY5)

Supplier: Bioss

Description: This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity).

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Catalog Number: (BOSSBS-7856R-CY5.5)

Supplier: Bioss

Description: Introduces molecular oxygen into polyunsaturated fatty acids. Exact substrate is not known.Tissue specificity:Predominantly expressed in skin.Involvement in diseaseDefects in ALOXE3 are a cause of non-bullous congenital ichthyosiform erythroderma (NCIE). NCIE is a non-bullous ichthyosis, a skin disorder characterized by abnormal cornification of the epidermis. Most affected individuals are born with a tight, shiny, translucent covering called collodion membrane. The collodion membrane subsequently evolves into generalized scaling and intense redness of the skin. Clinical features are milder than in lamellar ichthyoses and demonstrate a greater variability in the intensity of erythema, size and type of scales. In contrast to lamellar ichthyoses, scales are usually white, fine and powdery, and palms and soles are severely affected. Patients suffer from palmoplantar keratoderma, often with painful fissures, digital contractures, and loss of pulp volume.

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Catalog Number: (BOSSBS-3813R-CY7)

Supplier: Bioss

Description: UBC3B is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

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Catalog Number: (BOSSBS-7757R-FITC)

Supplier: Bioss

Description: Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-3813R-CY5)

Supplier: Bioss

Description: UBC3B is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-7757R-CY3)

Supplier: Bioss

Description: Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-3997R-CY3)

Supplier: Bioss

Description: Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-11367R-FITC)

Supplier: Bioss

Description: Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity).

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Catalog Number: (BOSSBS-15451R-CY3)

Supplier: Bioss

Description: Hepatitis C virus NS5B.

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Catalog Number: (BOSSBS-11365R-HRP)

Supplier: Bioss

Description: In all vertebrates, SV2 proteins are abundant, hydrophobic, membrane glycoproteins that are expressed as two major isoforms, SV2A and SV2B, and one minor isoform, SV2C. SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, independent of transmitter type. SV2A is abundantly expressed in the subcortex, specifically in the synaptic vesicles of all presynaptic nerve terminals, and also in most neuroendocrine secretory granules. SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex. SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates. SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation.

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Catalog Number: (BOSSBS-15493R-CY3)

Supplier: Bioss

Description: Catalyses the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.

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Catalog Number: (BOSSBS-3996R-CY7)

Supplier: Bioss

Description: Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. Malate dehydrogenase 1 (MDH1) is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-1615R-FITC)

Supplier: Bioss

Description: Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-3894R-FITC)

Supplier: Bioss

Description: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.

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Catalog Number: (BOSSBS-3841R-CY7)

Supplier: Bioss

Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Deubiquitinates activated NOTCH1, promoting its nuclear import, thereby acting as a positive regulator of Notch signaling.

UOM: 1 * 100 µl

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