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Catalog Number: (BOSSBS-7697R)
Supplier: Bioss
Description: Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-7697R-CY5)
Supplier: Bioss
Description: Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
UOM: 1 * 100 µl


Catalog Number: (AATB36312)
Supplier: AAT BIOQUEST
Description: Cell Meter™ No Wash and Probenecid-Free Endpoint Calcium Assay Kit enables homogeneous fluorescence-based assays for detecting intracellular calcium mobilization without the need to use kinetics reading mode.
UOM: 1 * 100 Tests


Catalog Number: (BOSSBS-15013R-A680)
Supplier: Bioss
Description: Regulator of UV-induced DNA damage response: acts as a 'reader' of ubiquitinated PCNA that enhances RAD18-mediated PCNA ubiquitination and translesion DNA synthesis (TLS). Recruited to sites of UV damage and interacts with ubiquitinated PCNA and RAD18, the E3 ubiquitin ligase that monoubiquitinates PCNA. Facilitates chromatin association of RAD18 and is required for efficient PCNA monoubiquitination, promoting a feed-forward loop to enhance PCNA ubiquitination and translesion DNA synthesis. Acts as a regulator of TLS by recruiting VCP/p97 to sites of DNA damage, possibly leading to extraction of DNA polymerase eta (POLH) by VCP/p97 to prevent excessive translesion DNA synthesis and limit the incidence of mutations induced by DNA damage.
UOM: 1 * 100 µl


Catalog Number: (AATB17650)
Supplier: AAT BIOQUEST
Description: Helixyte™ Green dsDNA Quantitation Assay Kit can be used for selectively detecting as little as 25 pg/ml of dsDNA in the presence of ssDNA, RNA, and free nucleotides.
UOM: 1 * 200 Tests


Catalog Number: (BOSSBS-0724R)
Supplier: Bioss
Description: Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway dowstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006). May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.
UOM: 1 * 100 µl


Catalog Number: (AATB16350)
Supplier: AAT BIOQUEST
Description: Nitric oxide (NO) is an important biological regulator involved in numbers of physiological and pathological processes.
UOM: 1 * 200 Tests


Catalog Number: (BOSSBS-7697R-A680)
Supplier: Bioss
Description: Chromatin reader that specifically recognises and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalises with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
UOM: 1 * 100 µl


Catalog Number: (620-1965)
Supplier: VWR Collection
Description: This stand-alone data logger records readings on a removable SD card. The card reader (supplied) plugs into any USB computer port for an instant report.
UOM: 1 * 1 items


Catalog Number: (661-0273)
Supplier: Mettler - Toledo
Description: SmartChemical RFID Reader, For: Mettler titrators
UOM: 1 * 1 items


Catalog Number: (BMGAQH-22410-1)
Supplier: BMG LABTECH
Description: The PHERAstar® FSX is our most sensitive multi-mode reader for high-throughput screening, combining this sensitivity with fast read times. The unique Optic Module system, Simultaneous Dual Emission, Enhanced Dynamic Range technology, UV/vis spectrometer, AAS System, and dedicated AlphaScreen® and TRF lasers, the PHERAstar FSX will perform your assay with ease and speed, even in 3456-well microplates.
UOM: 1 * 1 items

New Product


Catalog Number: (METT51192107)
Supplier: Mettler - Toledo
Description: LogStraight™ finger print reader, For: SevenExcellence™ meters
UOM: 1 * 1 items


Catalog Number: (BOSSBS-15013R-A350)
Supplier: Bioss
Description: Regulator of UV-induced DNA damage response: acts as a 'reader' of ubiquitinated PCNA that enhances RAD18-mediated PCNA ubiquitination and translesion DNA synthesis (TLS). Recruited to sites of UV damage and interacts with ubiquitinated PCNA and RAD18, the E3 ubiquitin ligase that monoubiquitinates PCNA. Facilitates chromatin association of RAD18 and is required for efficient PCNA monoubiquitination, promoting a feed-forward loop to enhance PCNA ubiquitination and translesion DNA synthesis. Acts as a regulator of TLS by recruiting VCP/p97 to sites of DNA damage, possibly leading to extraction of DNA polymerase eta (POLH) by VCP/p97 to prevent excessive translesion DNA synthesis and limit the incidence of mutations induced by DNA damage.
UOM: 1 * 100 µl


Catalog Number: (AATB14016)
Supplier: AAT BIOQUEST
Description: MUGlcU is a fluorogenic MU substrate for detecting glucuronidase in cell extracts and purified enzyme preparations using a fluorescence microplate reader or fluorometer.
UOM: 1 * 5 mg


Supplier: Molecular Devices
Description: EarlyTox™ Cell Viability Assay Kits are a family of fluorescence-based reagents for the assessment of cell viability, cell proliferation, and various apoptosis events using mammalian cells. Optimised for use with microplate readers, these assay kits employ a no-wash, homogeneous assay protocol that enables characterisation of a full concentration-response profile of test compounds.

Supplier: Thermo Fisher Scientific
Description: OPD (o-phenylenediamine dihydrochloride) is a water-soluble substrate for horseradish peroxidase (HRP) that produces a yellow-orange product detectable at 492 nm by ELISA plate readers.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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