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Catalog Number: (PRSI5151)
Supplier: ProSci Inc.
Description: Siglec11 Antibody: Siglecs are sialic acid-binding lectins of the immunoglobulin superfamily that are mainly expressed in cells of the hematopoietic system. Siglec11 is unlike other siglecs in that it binds specifically to alpha2-8-linked sialic acids and is not found in peripheral blood leukocytes but instead on macrophages of various tissues. Siglec11 is highly homologous to Siglec10 over their extracellular domain but not over their cytoplasmic domain, suggesting that Siglec11 arose through gene duplication followed by a recombination event involving another ancestral siglec gene. Following treatment of Siglec11-transfected cells with pervanadate, Siglec11 becomes tyrosine-phosphorylated and strongly associates with SHP-1 and SHP-2. At least five isoforms of Siglec11 are known to exist. Siglec11 antibody will not cross-react with Siglec10.
UOM: 1 * 100 µG


Catalog Number: (87857.290)
Supplier: VWR Chemicals
Description: Iodoplatinate reagent Reag. Ph. Eur. 1046300
UOM: 1 * 1 L

Catalog Number: (92504.290)
Supplier: VWR Chemicals
Description: Selenium reagent mixture for the determination of nitrogen acc. to Wieninger
UOM: 1 * 1 kg

Catalog Number: (87851.180)
Supplier: VWR Chemicals
Description: Hypophosphorous reagent Reag. Ph. Eur. 1045200
UOM: 1 * 100 mL

Catalog Number: (PRSI6535)
Supplier: ProSci Inc.
Description: ECRG4 Antibody: The esophageal cancer-related gene 4 (ECRG4), also known as Augurin, was identified through differential display screening between esophageal cancer and normal tissue. Hypermethylation of CpG sites in the ECRG4 promoter correlate with ECRG4 downregulation in numerous esophageal squamous cell carcinoma tissues.. In transfected cells, overexpression of ECRG4 induced G1 arrest, dephosphorylation of Rb and decreased expression of cyclins D1 and D3. Increased expression of ECRG4 in aged mouse brain is observed compared with young mouse brain. The increased ECRG4 level was accompanied by elevated senescence-associated acidic beta-galactosidase activity, suggesting that ECRG4 is involved in cellular differentiation and senescence.
UOM: 1 * 100 µG


Catalog Number: (87893.180)
Supplier: VWR Chemicals
Description: Phosphomolybdotungstic reagent Reag. Ph. Eur. 1065000
UOM: 1 * 100 mL

Catalog Number: (31072.268)
Supplier: VWR Chemicals
Description: Meyer's reagent for blood research
UOM: 1 * 500 mL

Catalog Number: (30969.261)
Supplier: VWR Chemicals
Description: Schiff reagent for analysis of aldehydes
UOM: 1 * 500 mL

Catalog Number: (1.02035.0100)
Supplier: Merck
Description: Dragendorff's reagent, spray reagent for TLC, Supelco®
UOM: 1 * 100 mL

Catalog Number: (PRSI3451)
Supplier: ProSci Inc.
Description: Caspase-4 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1 beta and IL-18. Caspase-4 was initially identified as a homologous protein to Caspase-1 and the C. elegans Ced-3 which could induce apoptosis in transfected cells. More recent studies have shown that it can be activated by ER stress and has been suggested to be involved in multiple neuronal pathologies such as Alzheimer's disease.
UOM: 1 * 100 µG


Catalog Number: (PRSI5685)
Supplier: ProSci Inc.
Description: TMEM184C Antibody: Anaplastic thyroid cancer is one of the most lethal forms of cancer, but the precise carcinogenic mechanism has not been identified. TMEM184C, also known as TMEM34, was identified in a cDNA microarray analysis as being down-regulated in anaplastic thyroid cancers compared to normal thyroid tissues. TMEM184C protein expression was also lower in cell lines derived from these types of cancers compared to that of normal thyroid tissues or cell lines based on other types of thyroid cancers. Furthermore, transfection of TMEM34 into KTA2 cells led to the inhibition of cell growth, suggesting that TMEM184C might act as a tumor suppressor in anaplastic thyroid cancers.
UOM: 1 * 100 µG


Catalog Number: (30989.236)
Supplier: VWR Chemicals
Description: Made of potassium bismuth iodide
UOM: 1 * 250 mL

Catalog Number: (E530-1L)
Supplier: VWR Chemicals
Description: Bradford's reagent, Biotechnology Grade for quantitative protein determination, for quantitative protein determination
UOM: 1 * 1 L

Catalog Number: (31360.264)
Supplier: VWR Chemicals
Description: Folin-Ciocalteu's reagent for analysis of phenols
UOM: 1 * 500 mL

Catalog Number: (ICNA091682049)
Supplier: MP Biomedicals
Description: Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. The 100 mM solution should be diluted 1:100 for most cell culture. The use of sodium pyruvate in Wallen fermentation medium to enhance the conversion of oleic acid to 10-ketostearic acid by <i>Bacillus sphaericus</i> has been described. A protocol that uses sodium pyruvate to establish stably transfected human B cell lines has been published. It improves coliform recovery when present in culture medium.
UOM: 1 * 100 mL

SDS


Supplier: VWR Chemicals
Description: Luff-Schoorl's reagent for quantitative determination of reducing sugars
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
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Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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