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Product Image-SCTV106678

Built-in signalbox and switch amplifiers, SymLine®

Supplier: S.C.A.T.
Description: Monitor two filling levels at once. Perfect integration into lab furniture with the Built-In signalbox and switch amplifier.

Product Image-817-5003

VWR®, Labels, Cryo

Catalog Number: (817-5003)
Supplier: VWR Collection
Description: The labels and adhesive have been designed to withstand temperatures from –196 to +121 °C. VWR® labels are ideal for all cryostorage, and can also be used in most incubators.
UOM: 1 * 600 items
Image Unavailable-MULC14713

Transport Box

Catalog Number: (MULC14713)
Supplier: MULTIROIR
Description: <p>This polypropylene case is a solution for securely storing and transporting sensitive equipment, thanks to the option of installing different types of foam.</p>
UOM: 1 * 4 items
Image Unavailable-BOSSBS-8476R-FITC

Anti-FBXL21 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-8476R-FITC)
Supplier: Bioss
Description: FBL3B is a 434 amino acid protein encoded by the human gene FBXL21. FBL3B contains one 40 amino acid F-box region, making it a member of the F-box family. FBL3B also contains three LRR (leucine-rich) repeats. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. FBL3B is a substrate-recognition component of the SCF complex that interacts with Skp1 p19 and CUL-1. FBL3B is also associated with expression and regulation of circadian and cryptochrome proteins.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9084R-CY7

Anti-FBXW12 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-9084R-CY7)
Supplier: Bioss
Description: Belonging to the F-box family of proteins, FBXO35 (F-box only protein 35), also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), is a 464 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO35 can directly interact with Skp1 p19 and CUL-1. FBXO35 is ubiquitously expressed at low levels in most human tissues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9084R-CY5.5

Anti-FBXW12 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-9084R-CY5.5)
Supplier: Bioss
Description: Belonging to the F-box family of proteins, FBXO35 (F-box only protein 35), also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), is a 464 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO35 can directly interact with Skp1 p19 and CUL-1. FBXO35 is ubiquitously expressed at low levels in most human tissues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9088R

Anti-FBXO28 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-9088R)
Supplier: Bioss
Description: FBXO28 is a member of the F-box protein family. Such proteins are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8393R-FITC

Anti-FBXW2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-8393R-FITC)
Supplier: Bioss
Description: F box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F box proteins have been shown to be critical for the ubiquitin mediated degradation of cellular regulatory proteins. In fact, F box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F box proteins. A large family of mammalian F box proteins has recently been identified and classified into three groups based on the presence of either the WD 40 repeats, the leucine rich repeats, or the presence or absence of other protein protein interacting domains. The FBXW2 gene product, the second identified member of the F box gene family, contains multiple WD 40 repeats.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7894R

Anti-CDCA3 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-7894R)
Supplier: Bioss
Description: CDCA3 (Cell division cycle associated 3) is an F-box-like protein which is required for entry into mitosis. It is associated with SKP1 as part of a SCF (SKP1-cullin-F-box) protein ligase complex, and is required for the ubiquitination and degradation of the CDK1 inhibitory tyrosine kinase WEE1 at G2/M phase.
UOM: 1 * 100 µl
Product Image-BRDY145580

Group lockout box, wall-mountable, SAFETY REDBOX®

Supplier: Brady
Description: This wall-mountable and portable lock box features a quick release internal slide button that allows the lockbox to be carried to the point of need.

Image Unavailable-BOSSBS-8393R-HRP

Anti-FBXW2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-8393R-HRP)
Supplier: Bioss
Description: F box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F box proteins have been shown to be critical for the ubiquitin mediated degradation of cellular regulatory proteins. In fact, F box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F box proteins. A large family of mammalian F box proteins has recently been identified and classified into three groups based on the presence of either the WD 40 repeats, the leucine rich repeats, or the presence or absence of other protein protein interacting domains. The FBXW2 gene product, the second identified member of the F box gene family, contains multiple WD 40 repeats.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9106R

Anti-ASB13 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-9106R)
Supplier: Bioss
Description: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B/C complex. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. The largest family of SOCS box-containing proteins is the ankyrin repeat and SOCS box-containing (ASB) protein family. ASB-13 (ankyrin repeat and SOCS box-containing 13) is a 278 amino acid member of the ASB family that contains one SOCS box domain and six ANK repeats. Existing as multiple isoforms, ASB-13 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8396R-A750

Anti-Fbx15 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-8396R-A750)
Supplier: Bioss
Description: FBXO15, also known as FBX15, is a 434 amino acid protein that contains one C-terminal F-box domain and belongs to the F-box family of proteins. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO15 can directly interact with Skp1 p19 and CUL-1. In addition, FBXO15 is a target of the transcription factor Oct-3/4, however, it does not appear to be essential for early development and fertility.
UOM: 1 * 100 µl
Product Image-MLDV6590-0145

Accessories for SpectraMax® iD5

Supplier: Molecular Devices
Description: Standard filter set including two filter slides in a box

Image Unavailable-USBIT0703-56

Anti-TAF15 RNA Polymerase II, TATA Box Binding Protein Mouse Monoclonal Antibody [clone: 8C319]

Catalog Number: (USBIT0703-56)
Supplier: US Biological
Description: Anti-TAF15 RNA Polymerase II, TATA Box Binding Protein Mouse Monoclonal Antibody [clone: 8C319]
UOM: 1 * 50 µG
Image Unavailable-BOSSBS-13150R-A680

Anti-FBXO45 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-13150R-A680)
Supplier: Bioss
Description: Belonging to the F-box family of proteins, FBXO45 is a 286 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IB- and -catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO45 can directly interact with Skp1 p19 and CUL-1. FBXO45 has been shown to be an estrogen-induced gene.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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