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Anti-MYC Mouse Monoclonal Antibody (CF568) [clone: 9E10.]

Supplier: Biotium
Description: This antibody recognizes a transcription factor of 64-67 kDa, identified as c-myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.

Image Unavailable-BNC700596-100

Anti-MYC Mouse Monoclonal Antibody (CF770) [clone: 9E10.]

Supplier: Biotium
Description: This antibody recognizes a transcription factor of 64-67 kDa, identified as c-myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.

Image Unavailable-BOSSBS-8586R-A350

Anti-GIPC-2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-8586R-A350)
Supplier: Bioss
Description: GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8586R-A750

Anti-GIPC-2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-8586R-A750)
Supplier: Bioss
Description: GIPC2 is a 315 amino acid protein that localises to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9562R-HRP

Anti-LAPTM4A Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-9562R-HRP)
Supplier: Bioss
Description: Lysosomal-associated transmembrane protein 4A (LAPTM4A), also known as Golgi 4-transmembrane spanning transporter MTP, is a 233 amino acid protein belonging to the LAPTM5/LAPTM5 transporter family. LAPTM4A is subcellularly localized to the intracytoplasmic membrane and has the potential to reside in intracellular membrane-bound compartments. LAPTM4A is thought to function as a transporter of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of intracellular compartments. LAPTM4A is predicted to have four transmembrane domains, with the C-terminal domain being required for retention of the protein within intracellular membranes.
UOM: 1 * 100 µl
Image Unavailable-BNC400372-100

Anti-CD6 Mouse Monoclonal Antibody (CF640R) [clone: C6/372]

Supplier: Biotium
Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Image Unavailable-BOSSBS-1437R-CY5.5

Anti-MRP5/ABCC5 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-1437R-CY5.5)
Supplier: Bioss
Description: MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.
UOM: 1 * 100 µl
Product Image-241-7433

Clamps, three pronged

Supplier: USBECK Laborgeräte
Description: Zinc die-cast, powder coated.

Image Unavailable-BOSSBS-10516R-HRP

Anti-CALCR Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-10516R-HRP)
Supplier: Bioss
Description: This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
UOM: 1 * 100 µl
Image Unavailable-BNUB0771-100

Anti-CDKN1B Mouse Monoclonal Antibody (Purified) [clone: DCS-72.F6]

Supplier: Biotium
Description: Recognizes a 27 kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.

Image Unavailable-BNC400771-500

Anti-CDKN1B Mouse Monoclonal Antibody (CF640R) [clone: DCS-72.F6]

Supplier: Biotium
Description: Recognizes a 27 kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.

Image Unavailable-BNC041228-500

Anti-CD6 Mouse Monoclonal Antibody (CF405S) [clone: C6/372 3F7B5]

Supplier: Biotium
Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Image Unavailable-BOSSBS-1437R-A555

Anti-MRP5/ABCC5 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-1437R-A555)
Supplier: Bioss
Description: MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6096R-CY7

Anti-RNF139 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-6096R-CY7)
Supplier: Bioss
Description: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6096R-CY3

Anti-RNF139 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-6096R-CY3)
Supplier: Bioss
Description: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
UOM: 1 * 100 µl
Product Image-241-2550

Double bosshead

Catalog Number: (241-2550)
Supplier: Lenz Laborglas GmbH & CO.KG
Description: Bosshead made from tempered cast iron. For attaching reaction vessel clamps to support stands.
UOM: 1 * 1 items
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
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Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
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The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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