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Product Image-ENZOALX270426M001

Smoothened agonist ≥95%

Catalog Number: (ENZOALX270426M001)
Supplier: ENZO LIFE SCIENCES
Description: Smoothened ligand
UOM: 1 * 1 mg

New Product


Image Unavailable-APOSOR958890-1MG

Smoothened agonist

Supplier: Apollo Scientific
Description: Smoothened agonist

Image Unavailable-USBIS1014-63E

Anti-Smoothened Rabbit Polyclonal Antibody

Catalog Number: (USBIS1014-63E)
Supplier: US Biological
Description: Anti-Smoothened Rabbit Polyclonal Antibody
UOM: 1 * 100 µG
Image Unavailable-ENZOALX270436M001

SANT-2 ≥95%

Catalog Number: (ENZOALX270436M001)
Supplier: ENZO LIFE SCIENCES
Description: Smoothened inhibitor
UOM: 1 * 1 mg

New Product


Product Image-USBIS1014-63E3

Anti-Smoothened Rabbit Polyclonal Antibody

Catalog Number: (USBIS1014-63E3)
Supplier: US Biological
Description: Anti-Smoothened Rabbit Polyclonal Antibody
UOM: 1 * 50 µG
Image Unavailable-APOSBISN0158-50MG

Sonidegib

Supplier: Apollo Scientific
Description: Erismodegib, NVP-LDE225) is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human) in cell-free assays, respectively.

Image Unavailable-BOSSBS-2801R-A680

Anti-Smoothened homolog Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-2801R-A680)
Supplier: Bioss
Description: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
UOM: 1 * 100 µl
Product Image-ENZOALX420045M005

Purmorphamine ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES
Description: Smoothened activator.

New Product

Image Unavailable-BOSSBS-2801R-A750

Anti-Smoothened homolog Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-2801R-A750)
Supplier: Bioss
Description: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2801R-CY7

Anti-SMO Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-2801R-CY7)
Supplier: Bioss
Description: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2801R-CY3

Anti-SMO Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-2801R-CY3)
Supplier: Bioss
Description: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2801R-FITC

Anti-SMO Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-2801R-FITC)
Supplier: Bioss
Description: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2801R-HRP

Anti-SMO Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-2801R-HRP)
Supplier: Bioss
Description: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2801R-A488

Anti-SMO Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-2801R-A488)
Supplier: Bioss
Description: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6624R-A555

Anti-IHH Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-6624R-A555)
Supplier: Bioss
Description: Ihh is an intercellular signalling peptide essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Ihh induces the expression of parathyroid hormone-related protein (PTHRP) and is implicated in endochondral ossification, possibly regulating the balance between growth and ossification of the developing bones.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6624R-CY5

Anti-IHH Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-6624R-CY5)
Supplier: Bioss
Description: Ihh is an intercellular signalling peptide essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Ihh induces the expression of parathyroid hormone-related protein (PTHRP) and is implicated in endochondral ossification, possibly regulating the balance between growth and ossification of the developing bones.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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