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Image Unavailable-BOSSBS-7689R-FITC

Anti-KCNMB1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-7689R-FITC)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7689R-A350

Anti-KCNMB1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-7689R-A350)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7689R-CY3

Anti-KCNMB1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-7689R-CY3)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7689R-CY5

Anti-KCNMB1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-7689R-CY5)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7689R-CY7

Anti-KCNMB1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-7689R-CY7)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7689R-CY5.5

Anti-KCNMB1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-7689R-CY5.5)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Product Image-559-0006

Flow controllers

Supplier: PARKER HANNIFIN
Description: For regulating and distributing the clean air output from a Parker compressed air dryer, FT-IR purge gas generator or self contained lab gas generator. Manifold and single flow types are available. Manifold types allow clean gas, at the regulated pressure, into the manifold where independently adjustable flow controls may be set to serve three separate instruments. Single flow types include a pressure regulator and a single flow controller. Each flow controller is equipped with a triple scale pressure gauge for 0 - 7 bar (psig, kg/cm²), a pressure regulator and a flow meter mounted on a convenient bracket for wall or panel mount installations.

Image Unavailable-BOSSBS-7689R-A488

Anti-KCNMB1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-7689R-A488)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7689R-A555

Anti-KCNMB1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-7689R-A555)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Product Image-GRSG600407

Digital vacuum - / barometer, GMH3161-12

Catalog Number: (GRSG600407)
Supplier: Greisinger
Description: This handheld meter with integrated absolute pressure sensor is suitable for measurements in air and non corrosive and non ionizing gases and liquids.
UOM: 1 * 1 items
Product Image-MILFXX6700P01

Pressure vessels

Supplier: Merck
Description: Dispensing pressure vessels hold liquid for filtration through pressure-operated filter holders, if connected to an external pressure source. Used for large-volume filtration, reservoir for buffer or solvent dispensing.

Product Image-HEWLG1375-87305

Capillaries for LC systems

Supplier: Agilent
Description: Stainless steel capillaries are made of flexible stainless steel (0,6 mm OD) with ¹/₁₆" OD tubing at both ends to accept standard fittings.

Product Image-6674.0050

VWR®, Silicone grease, TECHNICAL

Catalog Number: (6674.0050)
Supplier: VWR Chemicals
Description: VWR® Chemicals silicone grease is a valve lubricant and sealant, often times used as a vacuum grease. It has good resistance to most chemicals, a wide service temperature range, low vapor pressure, low volatility and exceptional water resistance.
UOM: 1 * 50 g

SDS Certificates


Product Image-REST26371

High purity airgas VOC regulators

Supplier: Restek
Description: These single stage stainless steel VOC regulators features stainless steel diaphragm, two pressure gauges, CGA-180 fitting and Kel-F® seat.

Product Image-RMONRMZ1214E51

Environmental Monitoring Solutions, RmoniWeb Validated

Supplier: Rmoni
Description: Rmoni offers complete end-2-end sensor solutions to set up an Environmental Monitoring Solutions (EMS) in hospitals, laboratories, pharmacies and cleanrooms. Keeping track of all critical parameters including temperature, humidity and many more. Ensuring product and process integrity during storage, handling and as well as transportation.

Image Unavailable-34031-2ML-R

Organic reference standard, Aflatoxin M1 solution, analytical standard, Supelco®

Catalog Number: (34031-2ML-R)
Supplier: Merck
Description: Isoproturon-d₆ has been used as an internal standard in the analysis of pesticides in fine airborne particulate matter, using liquid extraction under pressure and liquid chromatographic–tandem mass spectrometric method (HPLC-MS-MS).
UOM: 1 * 2 mL

Certificates


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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