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Image Unavailable-BOSSBS-8060R-CY5

Anti-SAMHD1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-8060R-CY5)
Supplier: Bioss
Description: Putative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response. May play a role in mediating proinflammatory responses to TNF-alpha signaling.Tissue specificity:Expressed in heart, skeletal muscle, spleen, liver, small intestine, placenta, lung and peripheral blood leukocytes. No expression is seen in brain and thymus.Involvement in disease:Defects in SAMHD1 are the cause of Aicardi-Goutieres syndrome type 5 (AGS5) . A form of Aicardi-Goutieres syndrome, a genetically heterogeneous disease characterized by cerebral atrophy, leukoencephalopathy, intracranial calcifications, chronic cerebrospinal fluid (CSF) lymphocytosis, increased CSF alpha-interferon, and negative serologic investigations for common prenatal infection. Clinical features as thrombocytopenia, hepatosplenomegaly and elevated hepatic transaminases along with intermittent fever may erroneously suggest an infective process. Severe neurological dysfunctions manifest in infancy as progressive microcephaly, spasticity, dystonic posturing and profound psychomotor retardation. Death often occurs in early childhood.
UOM: 1 * 100 µl
Product Image-612-4548

VWR® Safetypette, Pipette Filler

Catalog Number: (612-4548)
Supplier: VWR Collection
Description: Pipette filler for glass and plastic pipettes from 1 to 100 ml.
UOM: 1 * 1 items
Image Unavailable-GREISWA5_1000

Swabs tubes

Supplier: Greiner Bio-One
Description: Swab in tubes suitable for the collection and transport of non-human bacteriological, serological, and cytological samples.

Image Unavailable-BOSSBS-1557G-CY5

Anti-HBsAg Goat Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-1557G-CY5)
Supplier: Bioss
Description: Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1557G-CY3

Anti-HBsAg Goat Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-1557G-CY3)
Supplier: Bioss
Description: Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
UOM: 1 * 100 µl
Product Image-631-0724

VWR® Pipette Stands

Supplier: VWR Collection
Description: Pipette stands made of transparent acrylic.

Image Unavailable-BOSSBS-1557G-CY7

Anti-HBsAg Goat Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-1557G-CY7)
Supplier: Bioss
Description: Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
UOM: 1 * 100 µl
Product Image-613-4448

VWR® Powerpette Plus, Pipette Controller

Supplier: VWR Collection
Description: Pipette controller for glass and plastic pipettes from 1 to 100 ml.

Image Unavailable-USBI041488

Anti-SDCCAG1 Rabbit Polyclonal Antibody

Catalog Number: (USBI041488)
Supplier: US Biological
Description: Anti-SDCCAG1 Rabbit Polyclonal Antibody
UOM: 1 * 200 µl
Product Image-612-7284

VWR® Pipette Filler, White/Blue

Catalog Number: (612-7284)
Supplier: VWR Collection
Description: The VWR® pipette filler provides precise fluid control at your fingertips.
UOM: 1 * 1 items
Product Image-612-4552

VWR® Powerpette Pro, Pipette Controller

Catalog Number: (612-4552)
Supplier: VWR Collection
Description: Pipette controller for glass and plastic pipettes from 1 to 100 ml.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-1557G-A750

Anti-HBsAg Goat Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-1557G-A750)
Supplier: Bioss
Description: Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1557G-A680

Anti-HBsAg Goat Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-1557G-A680)
Supplier: Bioss
Description: Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
UOM: 1 * 100 µl
Product Image-612-6117

VWR® Pipette Stand, Rotary

Supplier: VWR Collection
Description: This carousel pipette stand, made from ABS, can hold up to eight single-channel, four multi-channel, or a combination of both pipettes.

Image Unavailable-USBI133267

Anti-SGOL1 Rabbit Polyclonal Antibody

Catalog Number: (USBI133267)
Supplier: US Biological
Description: Anti-SGOL1 Rabbit Polyclonal Antibody
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8060R-FITC

Anti-SAMHD1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-8060R-FITC)
Supplier: Bioss
Description: Putative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response. May play a role in mediating proinflammatory responses to TNF-alpha signaling.Tissue specificity:Expressed in heart, skeletal muscle, spleen, liver, small intestine, placenta, lung and peripheral blood leukocytes. No expression is seen in brain and thymus.Involvement in disease:Defects in SAMHD1 are the cause of Aicardi-Goutieres syndrome type 5 (AGS5) . A form of Aicardi-Goutieres syndrome, a genetically heterogeneous disease characterized by cerebral atrophy, leukoencephalopathy, intracranial calcifications, chronic cerebrospinal fluid (CSF) lymphocytosis, increased CSF alpha-interferon, and negative serologic investigations for common prenatal infection. Clinical features as thrombocytopenia, hepatosplenomegaly and elevated hepatic transaminases along with intermittent fever may erroneously suggest an infective process. Severe neurological dysfunctions manifest in infancy as progressive microcephaly, spasticity, dystonic posturing and profound psychomotor retardation. Death often occurs in early childhood.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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