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Product Image-141-1602

SlimLine PLW 7111 Laboratory Glasswashers

Supplier: MIELE
Description: The PLW 7111 SlimLine laboratory washers offer a comprehensive and systematic solution for analytically pure reprocessing of laboratory glassware.

Product Image-590-0734

Accessories for SCAT Level Controls

Supplier: S.C.A.T.
Description: Necessary and helpful accessories for use with SCAT electronic level controls.

Product Image-MFLX72072-30

LeviFlow Single-Use Centrifugal Pump Accessories

Supplier: Avantor Fluid Handling
Description: Optimize performance of your Levitronix Centrifugal Pump.

CE Compliant

Product Image-734-3323

VWR®, Single-Use Transfer Hose with SterilEnz™ Connections

Supplier: VWR Collection
Description: Avantor's high pressure single-use transfer hose with Avantor SterilEnz™ connections maintain the durability of high pressure hose products while providing the benefits and flexibility of single-use assemblies.

Product Image-DRAE6809180

Accessories for portable single gas detector, X-am® 5100

Supplier: Dräger
Description: Electrochemical sensor (XS), Electrochemical sensor

Image Unavailable-IMECG2H-000

tempmate.®-GS2 Single-Use Temperature Data Logger

Catalog Number: (IMECG2H-000)
Supplier: tempmate
Description: <p>The tempmate.®-GS2 offers you the possibility to perform the worldwide* real-time monitoring of all relevant data. By setting individual alarm limits, you are alerted in real-time. Damage can therefore be clearly localised and identified. With continuous use, you can optimise your transport routes and internal processes.</p>
UOM: 1 * 1 items

New Product


Product Image-MFLX31201-64

Masterflex® Single-Use Sanitary Gaskets, TPE, Avantor®

Supplier: Avantor Fluid Handling
Description: Ensure a tight seal in your sanitary fluid line.

Certificates 3A Sanitary approval

Product Image-665-0330

Multi-parameter meters, handheld, U-50 series

Supplier: HORIBA
Description: These waterproof meters can measure and display up to 11 parameters simultaneously with one single probe. Thanks to their rugged design and their field replaceable sensors they are ideal for outdoor use, for example, when testing ground or surface water. Their compact size and the hand strap enable one-handed operation.

Image Unavailable-99311-0.1ML-F

Potassium ionophore I - cocktail A, Selectophore™ ion sensor material, Supelco®

Catalog Number: (99311-0.1ML-F)
Supplier: Merck
Description: Ready-to-use ion selective liquid for the preparation of microelectrodes in micropipettes
UOM: 1 * 0,1 mL
Product Image-MFLX19999-96

Masterflex® Single Use Tubing Pinch Clamps, Avantor®

Catalog Number: (MFLX19999-96)
Supplier: Avantor Fluid Handling
Description: Clamps are double bagged and ready for use in your cleanroom environment.
UOM: 1 * 1 items

Certificates CE certificate


Product Image-MFLX30719-04

Masterflex® Single-Use Filling Needles

Supplier: Avantor Fluid Handling
Description: A high-quality engineered solution for every application in the fill-finish workflow.

Certificates

Image Unavailable-BOSSBS-6634R-CY5

Anti-XPC Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-6634R-CY5)
Supplier: Bioss
Description: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6634R-A647

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-6634R-A647)
Supplier: Bioss
Description: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Product Image-MFLX76000-00

Masterflex® Single-Use Replacement Pump Heads for Quattroflow Pump Systems

Supplier: Avantor Fluid Handling
Description: Keep your Quattroflow™ pump system up and running with these quality replacement pump heads.

Product Image-171-2709

Accessories for VWR® Water Purification System

Catalog Number: (171-2709)
Supplier: VWR Collection
Description: FLODEM single-use demineralisation cartridge, VWR®
UOM: 1 * 1 items
Image Unavailable-734-3342

VWR®, Accessories for Avantor TopMixer Single-Use Open Top Mixing Systems

Supplier: VWR Collection
Description: Single-Use LDPE tank with bottom port, 50L, VWR®

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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