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Catalog Number: (OHAU30868077)
Supplier: OHAUS
Description: Large pan for Pioneer® high capacity balance
UOM: 1 * 1 items


Catalog Number: (BOROLULT570)
Supplier: Labcold
Description: The Labcold LULT570 is an upright style ultra-low temperature freezer with a 570 L capacity, featuring VIP insulation and cascade refrigeration. It offers five inner compartments, consumes 14,4 kWh/day, and comes with a three year parts and labor warranty.
UOM: 1 * 1 items

New Product


Supplier: Mettler - Toledo
Description: Robust bench top meter for accurate pH and ion determinations in the lab and near production.

Catalog Number: (PRSI48-323)
Supplier: ProSci Inc.
Description: SGKL/SGK3, also known as CISK for cytokine-independent survival kinase, is a SGK type protein kinase. The protein contains a lipid-binding phox homology (PX) domain, which is required for targeting SGKL/SGK3 protein to the endosomal compartment. SGKL/SGK3 functions downstream of the phosphoinositide 3-kinase (PI3K) cascade and has been implicated in cell survival. The protein has been shown to be phosphorylated and activated by 3-phosphoinositide-dependent protein kinase 1 (PDK1), and to a lesser extent insulin-like growth factor-1, in vitro. Activated SGKL/SGK3 has been shown to phosphorylate glycogen synthase kinase 3 beta (GSK-3beta) in vitro.
UOM: 1 * 50 µG


Catalog Number: (PRSI56-693)
Supplier: ProSci Inc.
Description: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. [provided by RefSeq].
UOM: 1 * 400 µl

New Product


Catalog Number: (PRSI30-133)
Supplier: ProSci Inc.
Description: NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI (3) kinase, which suggests its role in PI (3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI (3) kinase, which suggests its role in PI (3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
UOM: 1 * 50 µG


Catalog Number: (PRSI26-092)
Supplier: ProSci Inc.
Description: NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI (3) kinase, which suggests its role in PI (3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed. The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI (3) kinase, which suggests its role in PI (3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
UOM: 1 * 50 µG


Catalog Number: (PRSI48-322)
Supplier: ProSci Inc.
Description: SGKL/SGK3, also known as CISK for cytokine-independent survival kinase, is a SGK type protein kinase. The protein contains a lipid-binding phox homology (PX) domain, which is required for targeting SGKL/SGK3 protein to the endosomal compartment. SGKL/SGK3 functions downstream of the phosphoinositide 3-kinase (PI3K) cascade and has been implicated in cell survival. The protein has been shown to be phosphorylated and activated by 3-phosphoinositide-dependent protein kinase 1 (PDK1), and to a lesser extent insulin-like growth factor-1, in vitro. Activated SGKL/SGK3 has been shown to phosphorylate glycogen synthase kinase 3 beta (GSK-3beta) in vitro.
UOM: 1 * 50 µG


Catalog Number: (CAYM13645-10)
Supplier: Cayman Chemical
Description: PX 866 1 * 10 mg
UOM: 1 * 10 mg


Catalog Number: (CAYM13645-1)
Supplier: Cayman Chemical
Description: PX 866 1 * 1 mg
UOM: 1 * 1 mg


Catalog Number: (CAYM21204-10)
Supplier: Cayman Chemical
Description: PX-866-17OH 1 * 10 mg
UOM: 1 * 10 mg


Catalog Number: (CAYM21204-1)
Supplier: Cayman Chemical
Description: PX-866-17OH 1 * 1 mg
UOM: 1 * 1 mg


Catalog Number: (APOSBIP1009-250MG)
Supplier: Apollo Scientific
Description: PX-866 250mg pack 1 * 250 mg
UOM: 1 * 250 mg

New Product


Catalog Number: (CAYM13645-5)
Supplier: Cayman Chemical
Description: PX 866 1 * 5 mg
UOM: 1 * 5 mg


Catalog Number: (CAYM21204-5)
Supplier: Cayman Chemical
Description: PX-866-17OH 1 * 5 mg
UOM: 1 * 5 mg


Catalog Number: (ABCAAB142148-5)
Supplier: Abcam
Description: FK-866 1 * 5 mg
UOM: 1 * 5 mg


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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