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You Searched For: Midostaurin


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Midostaurin

Supplier: Apollo Scientific
Description: Semisynthetic derivate of Staurosporine. Inhibitor of PKC and cAMPK.

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Midostaurin ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Inhibitor of a variety of serine/threonine and tyrosine kinases, like protein kinase C (PKC), cyclic AMP-dependent protein kinase (PKA), S6 kinase, Akt (protein kinase B; PKB), epidermal growth factor receptor (EGFR) tyrosine kinase activity and others including KDR, VEGFR, PDGFR, c-kit and other receptor tyrosine kinases. Potently inhibits FLT-3 kinase including mutant forms found in acute myeloid leukemia in vitro and in vivo. Apoptosis inducer. Showed broad antiproliferative activity against various tumor cell lines. Selectively inhibits T lymphocyte production of TNF-α. Upregulates endothelial nitric oxide synthase (eNOS; NOS III). Abrogates tumor angiogenesis in vivo.

Image Unavailable-J62917.MX

Midostaurin 1 * 1 mg

Catalog Number: (J62917.MX)
Supplier: Thermo Fisher Scientific
Description: Midostaurin 1 * 1 mg
UOM: 1 * 1 mg

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MIDOSTAURIN HYDRATE 1 * 1 mg

Catalog Number: (SIALM1323-1MG)
Supplier: Merck
Description: MIDOSTAURIN HYDRATE 1 * 1 mg
UOM: 1 * 1 mg
Image Unavailable-J62917.X0

Midostaurin 1 * 5 mg

Catalog Number: (J62917.X0)
Supplier: Thermo Fisher Scientific
Description: Midostaurin 1 * 5 mg
UOM: 1 * 5 mg

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MIDOSTAURIN HYDRATE 1 * 5 mg

Catalog Number: (SIALM1323-5MG)
Supplier: Merck
Description: MIDOSTAURIN HYDRATE 1 * 5 mg
UOM: 1 * 5 mg
Image Unavailable-MDEXHY-10230

Midostaurin (PKC412 CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β /γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM[1][2]. Mido 1 * 100 mg

Catalog Number: (MDEXHY-10230)
Supplier: MEDCHEMEXPRESS
Description: Midostaurin (PKC412 CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β /γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM[1][2]. Mido 1 * 100 mg
UOM: 1 * 100 mg

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
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Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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