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Image Unavailable-BOSSBS-8590R-A680

Anti-RanBP7 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-8590R-A680)
Supplier: Bioss
Description: Importin 7 is a 1,038 amino acid protein encoded by the human gene IPO7. Importin-7 belongs to the importin b family and contains one importin N-terminal domain. Importin-7 functions in nuclear protein import, either by acting as an autonomous nuclear transport receptor or as an adapter-like protein in association with the Importin b subunit KPNB1. Acting autonomously, Importin-7 is thought to serve itself as receptor for nuclear localisation signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to Importin-7, the Importin-7/substrate complex dissociates and Importin-7 is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. Importin-7 is a nuclear protein that is expressed in most tissues.
UOM: 1 * 100 µl
Image Unavailable-ABCAAB250479-1

Anti-Heterogeneous Nuclear Ribonucleoprotein (A1-like) Rabbit Monoclonal Antibody [clone: EPR13673-33]

Catalog Number: (ABCAAB250479-1)
Supplier: Abcam
Description: Anti-Heterogeneous Nuclear Ribonucleoprotein (A1-like) Rabbit Monoclonal Antibody [clone: EPR13673-33]
UOM: 1 * 1 mg
Image Unavailable-BOSSBS-8590R-A488

Anti-RANBP7 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-8590R-A488)
Supplier: Bioss
Description: Importin 7 is a 1,038 amino acid protein encoded by the human gene IPO7. Importin-7 belongs to the importin b family and contains one importin N-terminal domain. Importin-7 functions in nuclear protein import, either by acting as an autonomous nuclear transport receptor or as an adapter-like protein in association with the Importin b subunit KPNB1. Acting autonomously, Importin-7 is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to Importin-7, the Importin-7/substrate complex dissociates and Importin-7 is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. Importin-7 is a nuclear protein that is expressed in most tissues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5755R

Anti-Nucleoprotein TPR Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-5755R)
Supplier: Bioss
Description: Component of the cytoplasmic fibrils of the nuclear pore complex implicated in nuclear protein import. Its N-terminus is involved in activation of oncogenic kinases. Plays a role in the mitotic spindle checkpoint.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11678R

Anti-NUP107 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-11678R)
Supplier: Bioss
Description: Nuclear pore complexes (NPCs) are the channels for the bi-directional movement of macromolecules between the nucleus and cytoplasm, and contain more than 100 different subunits. Many of them belong to a family called nucleoporins, which are characterized by the presence of O-linked N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). Nuclear pore complex protein Nup107 (Nucleoporin Nup107) is an essential part of the nuclear pore complex which is composed of Nup133, Nup160, Nup107 and Nup96. Nup107 is active in assembling peripheral proteins into this complex. The protein, located on both the nuclear and cytoplasmic sides of the pore, is important in RNA export.
UOM: 1 * 100 µl
Image Unavailable-ABCAAB215755-500

Anti-Human Nuclear Antigen Mouse Monoclonal Antibody [clone: 235-1] (PE)

Catalog Number: (ABCAAB215755-500)
Supplier: Abcam
Description: Anti-Human Nuclear Antigen Mouse Monoclonal Antibody [clone: 235-1] (PE)
UOM: 1 * 500 µl
Image Unavailable-ABCAAB190725-500

Anti-Nuclear Membrane Marker Mouse Monoclonal Antibody [clone: NM97]

Catalog Number: (ABCAAB190725-500)
Supplier: Abcam
Description: Anti-Nuclear Membrane Marker Mouse Monoclonal Antibody [clone: NM97]
UOM: 1 * 500 µl
Image Unavailable-ABCAAB232034-100

Anti-Nuclear Matrix Protein p84 Rabbit Monoclonal Antibody [clone: EPR5662(2)]

Catalog Number: (ABCAAB232034-100)
Supplier: Abcam
Description: Anti-Nuclear Matrix Protein p84 Rabbit Monoclonal Antibody [clone: EPR5662(2)]
UOM: 1 * 100 µG
Product Image-USBIN6889-82N-PE

Anti-Nuclear Receptor LXR beta Rabbit Polyclonal Antibody (PE (Phycoerythrin))

Catalog Number: (USBIN6889-82N-PE)
Supplier: US Biological
Description: Anti-Nuclear Receptor LXR beta Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM: 1 * 200 µl
Product Image-USBIN6889-82N-FITC

Anti-Nuclear Receptor LXR beta Rabbit Polyclonal Antibody (FITC (Fluorescein))

Catalog Number: (USBIN6889-82N-FITC)
Supplier: US Biological
Description: Anti-Nuclear Receptor LXR beta Rabbit Polyclonal Antibody (FITC (Fluorescein))
UOM: 1 * 200 µl
Image Unavailable-BOSSBS-3695R-CY5

Anti-KPNB1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-3695R-CY5)
Supplier: Bioss
Description: NTF97 is involved in nuclear protein import, either by associating itself with an adapter protein (for example, importin-alpha subunit which binds to nuclear localization signals (NLS) in cargo substrates), or by acting autonomously as a nuclear transport receptor (serves as NLS receptor, docking of the importin/substrate complex to the nuclear pore complex).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11132R-A647

Anti-LMNB2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-11132R-A647)
Supplier: Bioss
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11132R-A350

Anti-LMNB2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-11132R-A350)
Supplier: Bioss
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
UOM: 1 * 100 µl
Product Image-E895-100G

Neutral red, Certifiable Grade

Catalog Number: (E895-100G)
Supplier: VWR Chemicals
Description: A cationic azine dye slightly soluble in water and ethanol. Used as a weak nuclear stain and as a supravital stain of fresh peripheal blood.
UOM: 1 * 100 g

SDS Certificates


Product Image-786-260

FOCUS™ SubCell, protein fractionation kit

Catalog Number: (786-260)
Supplier: G-Biosciences
Description: FOCUS™ SubCell for the fractionation of mitochondrial, nuclear, and cytosolic soluble and membrane proteins.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-10151R-A680

Anti-Exportin 1/CRM1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-10151R-A680)
Supplier: Bioss
Description: Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Involved in U3 snoRNA transport from Cajal bodies to nucleoli. Binds to late precursor U3 snoRNA bearing a TMG cap. Several viruses, among them HIV-1, HTLV-1 and influenza A use it to export their unspliced or incompletely spliced RNAs out of the nucleus. Interacts with, and mediates the nuclear export of HIV-1 Rev and HTLV-1 Rex proteins. Involved in HTLV-1 Rex multimerization.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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