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Image Unavailable-BOSSBS-1032R-A647

Anti-INHA Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-1032R-A647)
Supplier: Bioss
Description: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Inhibin deficient mice are viable but are acutely sensitive to development of gonadal sex-cord stromal tumors.
UOM: 1 * 100 µl
Product Image-99901.030

VWR®, Withdrawal System for 30 L Stainless Steel Barrels, Horizontal

Catalog Number: (99901.030)
Supplier: VWR Chemicals
Description: Specially developed solvent withdrawal system with manual pressure build-up for VWR® returnable 30 L stainless steel barrels.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-3902R-HRP

Anti-DIO3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-3902R-HRP)
Supplier: Bioss
Description: Dio3 belongs to the iodothyronine deiodinase family. It has an essential role for regulation of thyroid hormone inactivation during embryological development in that it catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. Dio3 may play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones and has been linked to the development of consumptive hypothyroidism in both infants and adults.
UOM: 1 * 100 µl
Product Image-91280.154

Palladium matrix modifier 2 g/L in nitric acid 1% [99,999% Pd(NO₃)₂], ARISTAR® for graphite furnace AAS

Catalog Number: (91280.154)
Supplier: VWR Chemicals
Description: The VWR® Matrix modifier solutions have especially been developed for use in GF-AAS to eliminate matrix effects. They can be used either diluted or as mixtures.
UOM: 1 * 50 mL

SDS Certificates


Product Image-1.00267.0001

Colour reference solutions, ready to use, according to Ph. Eur., Certipur®, Supelco®

Supplier: Merck
Description: Certipur® colour reference solutions are developed for ‘Method 1’ as described in chapter 2.2.2 of the European Pharmacopoeia.

SDS Certificates

Image Unavailable-BOSSBS-0735R-A647

Anti-FGF8 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-0735R-A647)
Supplier: Bioss
Description: Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (By similarity). Cooperates with Wnt-1 in mouse mammary tumor virus-induced murine mammary tumorigenesis.
UOM: 1 * 100 µl
Product Image-99901.010

VWR®, Withdrawal System for 10 L Stainless Steel Barrels, Horizontal

Catalog Number: (99901.010)
Supplier: VWR Chemicals
Description: Specially developed solvent withdrawal system with manual pressure build-up for VWR® returnable 10 L stainless steel barrels.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-0735R-FITC

Anti-FGF8 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-0735R-FITC)
Supplier: Bioss
Description: Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (By similarity). Cooperates with Wnt-1 in mouse mammary tumor virus-induced murine mammary tumorigenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12147R-A750

Anti-ZIC5 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-12147R-A750)
Supplier: Bioss
Description: Zic5 (zinc finger protein of the cerebellum 5) is a C2H2 zinc finger transcription factor that influences development of the neural crest. Zic family members are abundant in developing and adult cerebellum. Zic family members are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. Zic5 is closely linked to Zic2, a related family member on chromosome 13.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12147R-A680

Anti-ZIC5 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-12147R-A680)
Supplier: Bioss
Description: Zic5 (zinc finger protein of the cerebellum 5) is a C2H2 zinc finger transcription factor that influences development of the neural crest. Zic family members are abundant in developing and adult cerebellum. Zic family members are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. Zic5 is closely linked to Zic2, a related family member on chromosome 13.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12147R-A488

Anti-ZIC5 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-12147R-A488)
Supplier: Bioss
Description: Zic5 (zinc finger protein of the cerebellum 5) is a C2H2 zinc finger transcription factor that influences development of the neural crest. Zic family members are abundant in developing and adult cerebellum. Zic family members are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. Zic5 is closely linked to Zic2, a related family member on chromosome 13.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12147R-CY5

Anti-ZIC5 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-12147R-CY5)
Supplier: Bioss
Description: Zic5 (zinc finger protein of the cerebellum 5) is a C2H2 zinc finger transcription factor that influences development of the neural crest. Zic family members are abundant in developing and adult cerebellum. Zic family members are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. Zic5 is closely linked to Zic2, a related family member on chromosome 13.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0485R-FITC

Anti-EPHA2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-0485R-FITC)
Supplier: Bioss
Description: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration. During development, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. Involved for instance in angiogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development. Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11596R-CY3

Anti-OTX1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11596R-CY3)
Supplier: Bioss
Description: Transcription factors, OTX1 and OTX2, are two murine homologs of the Drosophila orthodenticle (OTD), show a limited amino acid sequence divergence. OTX1 and OTX2 play an important role during early and later events required for proper brain development in that they are involved in the processes of induction, specification and regionalization of the brain. OTX1 is involved in corticogenesis, sensory organ development and pituitary functions, while OTX2 is necessary earlier in development, for the correct anterior neural plate specification and organization of the primitive streak. OTX2 is also required in the early specification of the neuroectoderm, which is destined to become the fore-midbrain, and both OTX1 and OTX2 co-operate in patterning the developing brain through a dosage-dependent mechanism. A molecular mechanism depending on a precise threshold of OTX proteins is necessary for the correct positioning of the isthmic region and for anterior brain patterning. The genes which encode OTX1 and OTX2 map to human chromosomes 2p15 and 14q21-q22, respectively.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11597R-CY3

Anti-OTX2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11597R-CY3)
Supplier: Bioss
Description: Transcription factors, OTX1 and OTX2, are two murine homologs of the Drosophila orthodenticle (OTD), show a limited amino acid sequence divergence. OTX1 and OTX2 play an important role during early and later events required for proper brain development in that they are involved in the processes of induction, specification and regionalization of the brain. OTX1 is involved in corticogenesis, sensory organ development and pituitary functions, while OTX2 is necessary earlier in development, for the correct anterior neural plate specification and organization of the primitive streak. OTX2 is also required in the early specification of the neuroectoderm, which is destined to become the fore-midbrain, and both OTX1 and OTX2 co-operate in patterning the developing brain through a dosage-dependent mechanism. A molecular mechanism depending on a precise threshold of OTX proteins is necessary for the correct positioning of the isthmic region and for anterior brain patterning. The genes which encode OTX1 and OTX2 map to human chromosomes 2p13 and 14q21-q22, respectively.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12401R

Anti-NLE1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-12401R)
Supplier: Bioss
Description: The Notch signaling pathway is an evolutionary conserved system that is involved in intracellular communication. Notch receptors play an important role in development and cell-fate decisions. Notchless is a loss-of-function mutant allele that encodes for protein NLE1 (notchless homolog 1). NLE1 is a 485 amino acid WD40-repeat protein that binds to the cytoplasmic domain of Notch, regulating its signaling activity in Drosophila melanogaster and in mice. Deletion of the NLE1 gene in mice during the early stages of development results in embryonic death, while gene deletion in the late stages of development leads to activation of a caspase-3-dependent apoptotic pathway. In plants, NLE1 is crucial for normal cellular growth and development. Under-expression during shoot proliferation causes pleiotropic defects such as delayed flowering and abnormal organ maturation. It may also play a role in 60S ribosomal subunit biogenesis in yeast. NLE1 contains eight WD40 domains and produces one isoform due to alternative splicing.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
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