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Catalog Number: (BOSSBS-9149R-CY5.5)
Supplier: Bioss
Description: TRIM35 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1, a B-box type 2 and a coiled-coil region. TRIM35 may play a role as a tumor suppressor and is implicated in the cell death mechanism. There are two named isoforms.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-3989R-CY5.5)
Supplier: Bioss
Description: Glycogen synthase catalyzes the rate-limiting step in glycogen synthesis. Its activity is regulated by a complex phosphorylation-dephosphorylation mechanism and by allosteric stimulators and inhibitors. Two isozymes of synthase, a skeletal muscle type (Glycogen synthase 1 - GYS1) and a liver type (Glycogen synthase 2 - GYS2), have been identified.
UOM: 1 * 100 µl


Supplier: Brady
Description: These universal valve lockouts with cable and blocking arm are effective for a variety types of standard valves. Can also be used to lock out large levers, T-handles and hard-to-secure mechanical devices.

Catalog Number: (BOSSBS-2711R-CY7)
Supplier: Bioss
Description: Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-2054R-CY3)
Supplier: Bioss
Description: Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-3989R-A647)
Supplier: Bioss
Description: Glycogen synthase catalyzes the rate-limiting step in glycogen synthesis. Its activity is regulated by a complex phosphorylation-dephosphorylation mechanism and by allosteric stimulators and inhibitors. Two isozymes of synthase, a skeletal muscle type (Glycogen synthase 1 - GYS1) and a liver type (Glycogen synthase 2 - GYS2), have been identified.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-0351R-CY7)
Supplier: Bioss
Description: Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-6202R-A555)
Supplier: Bioss
Description: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-2711R-A680)
Supplier: Bioss
Description: Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defence mechanisms.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-2054R-A488)
Supplier: Bioss
Description: Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-4608R-HRP)
Supplier: Bioss
Description: Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-4608R-A488)
Supplier: Bioss
Description: Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-4608R-A680)
Supplier: Bioss
Description: Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13669R-CY3)
Supplier: Bioss
Description: Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-0108R-CY7)
Supplier: Bioss
Description: May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-5012R-CY3)
Supplier: Bioss
Description: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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