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MMP-13 inhibitor ≥99% (by HPLC)

Supplier: ENZO LIFE SCIENCES
Description: Potent MMP-13 inhibitor.

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Image Unavailable-ENZOBMLEI3020005

CL-82198 (MMP-13 inhibitor) ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: A novel and selective inhibitor of MMP-13 (89% at 33 µM). Acts via binding to the S1' pocket of MMP-13 without metal chelation.

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Image Unavailable-ENZOBMLAK4120001

Matrix Metalloproteinase-13 (MMP-13) colorimetric drug discovery kit

Catalog Number: (ENZOBMLAK4120001)
Supplier: ENZO LIFE SCIENCES
Description: A QuantiZyme™ Assay System. The MMP-13 Colorimetric Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-13 (MMP-13, collagenase-3) using a thiopeptide as a chromogenic substrate.
UOM: 1 * 1 KIT

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Image Unavailable-ENZOBMLAK4130001

Matrix Metalloproteinase-13 (MMP-13) fluorometric drug discovery kit

Catalog Number: (ENZOBMLAK4130001)
Supplier: ENZO LIFE SCIENCES
Description: A QuantiZyme™ Assay System. The MMP-13 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-13 (MMP-13, collagenase-3) using a quenched fluorogenic peptide: OmniMMP™ fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties.
UOM: 1 * 1 KIT

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Image Unavailable-ENZOBMLP1450001

Cathepsin D & E substrate (fluorogenic)

Catalog Number: (ENZOBMLP1450001)
Supplier: ENZO LIFE SCIENCES
Description: Quenched fluorogenic substrate for cathepsin D (kcat/Km=1,09×10 M-1s-1) and cathepsin E (kcat/Km=1,56×10 M-1s-1). Mca fluorescence is quenched by the Dnp group until cleavage separates them. Activity of the two enzymes on this substrate can be distinguished by the use of Ascaris pepsin inhibitor, which inhibits cathepsin E, but not cathepsin D. This substrate is also cleaved by MMP-2, MMP-3, MMP-9, but not MMP-1 nor MMP-13. This substrate is useful for inhibitor screening and kinetic analysis. Ex.: 320-340 nm, Em.: 393-420 nm. Mca-Pro-Leu-OH (BML-P127) can be used to calibrate for Mca fluorescence.
UOM: 1 * 1 mg

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Image Unavailable-ENZOBMLP2350001

ADAM Substrate

Catalog Number: (ENZOBMLP2350001)
Supplier: ENZO LIFE SCIENCES
Description: Fluorogenic substrate for ADAM8 (kcat/Km = 1,0×105 M-1s-1), ADAM10 (6,2×103), ADAM12 (2,8×105), TACE (TNF-α converting enzyme, ADAM17) (4,3×105), and likely other ADAMs, especially those that cleave TNF-α type sequences. Also efficiently cleaved by MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, and MMP-14. FAM fluorescence is quenched by the Dabcyl group until cleavage separates them. Ex.: 485 nm, Em.: 530 nm. This substrate is useful for inhibitor screening and kinetic analysis.
UOM: 1 * 1 mg

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Product Image-ENZOBMLP1320500

TACE substrate (fluorogenic)

Catalog Number: (ENZOBMLP1320500)
Supplier: ENZO LIFE SCIENCES
Description: Fluorogenic substrate for TACE (ADAM17) (between Ala-Val), as well as MMP-3, MMP-7, MMP-12, and MMP-17, but not for ADAM19, MMP-13, nor MMP-14. Similar substrates are also cleaved by ADAM10, ADAM8 and ADAM9, and MMP-1, -2, and -9. This quenched substrate is useful for TACE inhibitor screening and kinetic analysis. Ex: 328 nm, Em: 393 nm, although the following Ex/Em have been used: 320-340/400-420. Also available: OMNIMMP® Fluorogenic Control peptide (BML-P127).
UOM: 1 * 0,5 mg

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Image Unavailable-444252-1

MMP-9/MMP-13 inhibitor I ≥95% (by HPLC), Millipore®

Catalog Number: (444252-1)
Supplier: Merck Millipore (Calbiochem‎)
Description: A piperazine-based, cell-permeable, and highly potent inhibitor of MMP-9 (IC₅₀=900 pM) and MMP-13 (IC₅₀=900 pM).
UOM: 1 * 1 mg
Image Unavailable-PRSI91-415

Human recombinant TIMP2 (from cells)

Catalog Number: (PRSI91-415)
Supplier: ProSci Inc.
Description: Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
UOM: 1 * 50 µG
Image Unavailable-PRSI92-603

Mouse recombinant TIMP1

Catalog Number: (PRSI92-603)
Supplier: ProSci Inc.
Description: Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16. TIMP-1 does not act on MMP-14.
UOM: 1 * 50 µG
Image Unavailable-PRSI91-412

Human recombinant TIMP1 (from cells)

Catalog Number: (PRSI91-412)
Supplier: ProSci Inc.
Description: Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16. TIMP-1 does not act on MMP-14.
UOM: 1 * 50 µG
Image Unavailable-ENZOENZCHM1330001

MMP-​9 inhibitor I ≥97% (by HPLC)

Catalog Number: (ENZOENZCHM1330001)
Supplier: ENZO LIFE SCIENCES
Description: Cell-permeable, potent, selective, and reversible MMP-9 inhibitor.
UOM: 1 * 1 mg

New Product


Image Unavailable-ENZOALX260165M005

MMP-3 inhibitor ≥95% (by HPLC)

Catalog Number: (ENZOALX260165M005)
Supplier: ENZO LIFE SCIENCES
Description: Inhibitor of matrix metalloproteinase 3 (MMP-3) (IC50=5µM).
UOM: 1 * 5 mg

New Product


Image Unavailable-ENZOBMLAK3080001

MMP inhibitor profiling kit

Catalog Number: (ENZOBMLAK3080001)
Supplier: ENZO LIFE SCIENCES
Description: The MMP inhibitor profiling kit, fluorometric RED is a complete assay system designed to examine the specificity of inhibitors against a panel of ten matrix metalloproteinase enzymes, using a quenched fluorogenic substrate OMNIMMP® RED.
UOM: 1 * 1 KIT

New Product


Image Unavailable-ENZOBMLAK0160001

MMP Inhibitor profiling kit, fluorometric

Catalog Number: (ENZOBMLAK0160001)
Supplier: ENZO LIFE SCIENCES
Description: A QUANTIZYME® Assay System Complete assay system designed to examine the specificity of inhibitors against a panel of ten matrix metalloproteinase enzymes. The assays are performed in a convenient 96-well microplate format using a sensitive fluorogenic substrate . Included are active MMP enzymes, assay buffer, a prototypic control inhibitor (NNGH3), and a detailed instruction booklet.
UOM: 1 * 1 KIT

New Product


Image Unavailable-ENZOBMLAK0150001

MMP Inhibitor profiling kit, colorimetric

Catalog Number: (ENZOBMLAK0150001)
Supplier: ENZO LIFE SCIENCES
Description: A QUANTIZYME® Assay System Complete assay system designed to examine the specificity of inhibitors against a panel of ten matrix metalloproteinase enzymes. The assays are performed in a convenient 96-well microplate format using a chromogenic substrate1,2 detected at 412 nm. Included are active MMP enzymes, assay buffer, a prototypic control inhibitor (NNGH3), and a detailed instruction booklet.
UOM: 1 * 1 KIT

New Product


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
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Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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