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Image Unavailable-BOSSBS-10307R-HRP

Anti-CLCN5 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-10307R-HRP)
Supplier: Bioss
Description: The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, 3q28, 4q32, Xp22.3, Xp11.23-p11.22, 1p36 and 16p13, respectively. CLC1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC2 is highly expressed in the epithelia of several organs including lung, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis. CLC3 expression is particularly abundant in neuronal tissue, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC5 lead to Dent’s disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC6 and CLC7 are broadly expressed in several tissues including testis, kidney, brain and muscle.
UOM: 1 * 100 µl
Image Unavailable-14697.06

Manganese(II) chloride, ultra dry ≥99.998% (metals basis)

Supplier: Thermo Fisher Scientific
Description: Manganese(II) chloride, ultra dry ≥99.998% (metals basis)

SDS Certificates

Image Unavailable-35701.18

Iron(II) chloride, ultra dry ≥99.99% (metals basis)

Supplier: Thermo Fisher Scientific
Description: Iron(II) chloride, ultra dry ≥99.99% (metals basis)

SDS Certificates

Image Unavailable-13667.06

Cadmium(II) chloride, ultra dry ≥99.998% (metals basis)

Supplier: Thermo Fisher Scientific
Description: Cadmium(II) chloride, ultra dry ≥99.998% (metals basis)

SDS Certificates

Image Unavailable-1.09211.1000

Azure II for microscopy (C.I.52010/52015)

Supplier: Merck
Description: Azure II (C.I. 52010/ 52015) is a dry dye for the preparation of a color staining solution used for the staining of blood and bone marrow smears of human origin. The dye is a CE certified IVD product and has a constant dye content and a reliable high quality, which is one of the major precondition for a reproducible diagnostic staining.

SDS

Image Unavailable-35713.22

Nickel(II) chloride, ultra dry ≥99.9% (metals basis)

Supplier: Thermo Fisher Scientific
Description: Nickel(II) chloride, ultra dry ≥99.9% (metals basis)

SDS Certificates

Image Unavailable-BOSSBS-6191R-CY7

Anti-SETD7 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-6191R-CY7)
Supplier: Bioss
Description: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. Also able to demethylated 'Lys-372' of p53/TP53 in vitro.
UOM: 1 * 100 µl
Image Unavailable-C6914-1KG

Cesium chloride ≥98% Grade II, Sigma-Aldrich®

Supplier: SIGMA ALDRICH MICROSCOPY
Description: It is used for the preparation of electrically conducting glasses. Used to make solutions for the separation of RNA from DNA by density gradient centrifugation.

Image Unavailable-BOSSBS-2509R-CY5

Anti-AIMP2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-2509R-CY5)
Supplier: Bioss
Description: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2509R-CY5.5

Anti-AIMP2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-2509R-CY5.5)
Supplier: Bioss
Description: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8241R-HRP

Anti-CTDSPL Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-8241R-HRP)
Supplier: Bioss
Description: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8241R-A488

Anti-CTDSPL Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-8241R-A488)
Supplier: Bioss
Description: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8869R-FITC

Anti-ITPR1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-8869R-FITC)
Supplier: Bioss
Description: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
UOM: 1 * 100 µl
Image Unavailable-10692.18

Cobalt(II) chloride hexahydrate ≥99.998% (metals basis), Puratronic®

Supplier: Thermo Fisher Scientific
Description: Cobalt(II) chloride hexahydrate ≥99.998% (metals basis), Puratronic®

SDS Certificates

Image Unavailable-36526.22

Manganese(II) chloride tetrahydrate 98.0-101.0% ACS

Supplier: Thermo Fisher Scientific
Description: Manganese(II) chloride tetrahydrate 98.0-101.0% ACS

SDS Certificates

Image Unavailable-12372.A3

Nickel(II) chloride hexahydrate ≥99.3% (metals basis)

Supplier: Thermo Fisher Scientific
Description: Nickel(II) chloride hexahydrate ≥99.3% (metals basis)

SDS Certificates

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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