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Image Unavailable-BOSSBS-10463R-FITC

Anti-HEXB chain A Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-10463R-FITC)
Supplier: Bioss
Description: Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10463R-A555

Anti-HEXB chain A Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-10463R-A555)
Supplier: Bioss
Description: Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8869R-CY5

Anti-ITPR1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-8869R-CY5)
Supplier: Bioss
Description: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
UOM: 1 * 100 µl
Image Unavailable-1.10648.0001

Test strips for carbonate hardness, MQuant®, Supelco®

Catalog Number: (1.10648.0001)
Supplier: Merck
Description: MQuant® (MQ) test strips can be considered as a mobile laboratory on a few square millimeters of plastic strip. As a screening method they provide the user with a rapid overview of the situation, which helps in making the choice of what, and perhaps if, further analysis is required, thereby leading to potentially substantial savings in time and analytical resources. The strip is a biologically-degradable polyester foil and the low reagent content, in the reaction zones, assists problem-free waste disposal.
UOM: 1 * 100 Tests

SDS Certificates


Image Unavailable-ENZOALX430049M025

Zinc protoporphyrin ≥95% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter.

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Image Unavailable-BOSSBS-8244R-CY5.5

Anti-CA11 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-8244R-CY5.5)
Supplier: Bioss
Description: Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA XI, also referred to as carbonic anhydrase-related protein 11 precursor (CA-RP XI) or carbonic anhydrase-related protein 2 (CA-RP II), is a member of the carbonic anhydrase family that lacks two of the three Zn-binding motifs essential for carbonic anhydrase activity. For this reason, CA XI does not exhibit catalytic activity. It is expressed primarily in brain but is also found in spinal cord and thyroid. CA XI may play a role in brain development.Tissue specificity:Expressed abundantly in the brain with moderate expression also present in spinal cord and thyroid.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8244R-CY7

Anti-CA11 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-8244R-CY7)
Supplier: Bioss
Description: Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA XI, also referred to as carbonic anhydrase-related protein 11 precursor (CA-RP XI) or carbonic anhydrase-related protein 2 (CA-RP II), is a member of the carbonic anhydrase family that lacks two of the three Zn-binding motifs essential for carbonic anhydrase activity. For this reason, CA XI does not exhibit catalytic activity. It is expressed primarily in brain but is also found in spinal cord and thyroid. CA XI may play a role in brain development.Tissue specificity:Expressed abundantly in the brain with moderate expression also present in spinal cord and thyroid.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0424R-CY7

Anti-MMP1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-0424R-CY7)
Supplier: Bioss
Description: Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0424R-CY5.5

Anti-MMP1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-0424R-CY5.5)
Supplier: Bioss
Description: Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0424R-A647

Anti-MMP1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-0424R-A647)
Supplier: Bioss
Description: Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0424R-A750

Anti-MMP-1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-0424R-A750)
Supplier: Bioss
Description: Cleaves collagens of types I, Ii and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8869R-A488

Anti-ITPR1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-8869R-A488)
Supplier: Bioss
Description: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8241R-CY3

Anti-CTDSPL Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-8241R-CY3)
Supplier: Bioss
Description: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3509R-CY3

Anti-CTDSPL Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-3509R-CY3)
Supplier: Bioss
Description: Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3509R-CY5

Anti-CTDSPL Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-3509R-CY5)
Supplier: Bioss
Description: Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8241R

Anti-CTDSPL Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-8241R)
Supplier: Bioss
Description: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
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The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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