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Image Unavailable-324410-10

Dynasore ≥98% (by HPLC), Millipore®

Catalog Number: (324410-10)
Supplier: Merck Millipore (Calbiochem‎)
Description: Dynasore, also known as Dynamin inhibitor I, is a cell-permeable semicarbazone compound that inhibits the GTPase activity of dynamin1/2 (IC<sub>50</sub> ~15 µM) and Drp1. It has no significant effect against two other small GTPases, MxA and Cdc42.
UOM: 1 * 10 mg
Image Unavailable-BOSSBS-11132R-A350

Anti-LMNB2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-11132R-A350)
Supplier: Bioss
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11132R-A647

Anti-LMNB2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-11132R-A647)
Supplier: Bioss
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11132R-CY5

Anti-LMNB2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-11132R-CY5)
Supplier: Bioss
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11132R-A555

Anti-LMNB2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-11132R-A555)
Supplier: Bioss
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11132R-A488

Anti-LMNB2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-11132R-A488)
Supplier: Bioss
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11132R-CY3

Anti-LMNB2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11132R-CY3)
Supplier: Bioss
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
UOM: 1 * 100 µl
Product Image-172-0063

Milli-Q® IQ Element purification system

Supplier: Merck
Description: Milli-Q® IQ Element water purification and dispensing unit is designed to fit into your trace analysis workflow. The Milli-Q® IQ Element unit, combined with a Milli-Q® IQ 7 series water purification system, delivers analytical grade ultrapure water that is suitable for trace and ultra-trace elemental analyses, including ICP-MS, GF-AAS and trace IC.

Image Unavailable-DUPOD15466170/4X

TYVEK® IsoClean® frock with bound neck - model IC 270 B option MS (Clean-Processed and Sterile, Double bagged), White. Size 4XL 1 * 1 items

Catalog Number: (DUPOD15466170/4X)
Supplier: DuPont
Description: TYVEK® IsoClean® frock with bound neck - model IC 270 B option MS (Clean-Processed and Sterile, Double bagged), White. Size 4XL 1 * 1 items
UOM: 1 * 1 items

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Image Unavailable-BOSSBS-11132R-CY7

Anti-LMNB2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-11132R-CY7)
Supplier: Bioss
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11132R-FITC

Anti-LMNB2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-11132R-FITC)
Supplier: Bioss
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
UOM: 1 * 100 µl
Image Unavailable-95305-10L

Water, TraceSELECT™ for trace analysis, Riedel-de Haën™

Supplier: Honeywell Chemicals
Description: High purity solvents for speciation analysis by LC-ICP-MS. Rigorous purification procedures followed by UV spectroscopy, IC, and ICP-MS testing to assure high chemical purity and high UV transmittance. The blank values for metal traces in these solvents are in the ppb range or lower.

SDS Environmentally Preferable

Image Unavailable-BOSSBS-11132R-A680

Anti-Lamin B2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-11132R-A680)
Supplier: Bioss
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
UOM: 1 * 100 µl
Product Image-516-0584

Centrifugal devices, Nanosep® and Nanosep® MF

Supplier: Cytiva (Formerly Pall Lab)
Description: These devices are used for simple, reliable concentrating and desalting of 50 to 500 μl samples. Select the low protein binding Omega™ membrane for ultrafiltration applications. The Bio-Inert® membrane is ideal for microfiltration of biological solutions. The GHP membrane is ideal for sample preparation in analytical chemistry (HPLC, GC, IC and MS). It is suitable for aqueous, organic and aggressive organic samples, and for rapid processing of samples.

Product Image-GAINTRM25SBC1-50YE

Deep-Freeze Removable Tapes

Supplier: GA
Description: Removable lab tape for deep-freeze storage of cryo containers, including freezer boxes, tubes, vials, plastic bags, and other items intended for long-term storage in laboratory freezers and dry ice transportation. Writable using permanent cryo markers.

Image Unavailable-42105-1L

Methanol ≥99.9%, TraceSELECT™ for metal speciation analysis, Riedel-de Haën™

Catalog Number: (42105-1L)
Supplier: Honeywell Chemicals
Description: High purity solvents for speciation analysis by LC-ICP-MS. Rigorous purification procedures followed by UV spectroscopy, IC, and ICP-MS testing to assure high chemical purity and high UV transmittance. The blank values for metal traces in these solvents are in the ppb range or lower.
UOM: 1 * 1 L

SDS Environmentally Preferable


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
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The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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