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Product Image-478-5144

Dewar flasks, type GSS

Supplier: KGW
Description: Dewar flasks in stainless steel for storage and transport of liquid nitrogen, dry ice and other coolants. They are vacuum insulated and have a temperature range from −200 to +200 °C.

Image Unavailable-616-3357

Micro-Ubbelohde viscometers (DIN), Type No. 537 13, Capillary No. Ic, Constant K = 0.03, calibrated for automatic measurements 1 * 1 items

Catalog Number: (616-3357)
Supplier: SI Analytics
Description: Micro-Ubbelohde viscometers (DIN), Type No. 537 13, Capillary No. Ic, Constant K = 0.03, calibrated for automatic measurements 1 * 1 items
UOM: 1 * 1 items
Image Unavailable-CAYM15428-50

Lamotrigine ≥98%

Supplier: Cayman Chemical
Description: Lamotrigine is an inhibitor of voltage-gated sodium channels (Na<sub>v</sub>), blocking human Na<sub>v</sub>1,2, Na<sub>v</sub>1,5, and Na<sub>v</sub>1,8 with IC<sub>50</sub> values of 10, 62, and 96 μM, respectively.

Image Unavailable-BWRLBS60819

The CED/ICE family of cysteine proteases plays a pivotal role in mediating apoptosis through the proteolysis of specific targets. 1 * 100 µG

Catalog Number: (BWRLBS60819)
Supplier: Bioworld Technology
Description: The CED/ICE family of cysteine proteases plays a pivotal role in mediating apoptosis through the proteolysis of specific targets. 1 * 100 µG
UOM: 1 * 100 µG
Product Image-GAINA4RCL-23T1-WH

Removable Cryogenic Labels for Laser Printers

Supplier: GA
Description: Removable cryo labels provided in A4 sheet format for printing with laser printers. Ideal for long-term storage in liquid phase and vapor phase liquid nitrogen (−196 °C), lab freezers (−80 °C), and on dry ice.

Product Image-479-0495

Dewars, Dilvac

Supplier: DAY IMPEX
Description: Multi-purpose container, suitable for LN₂ or dry-ice. High-quality borosilicate glass inner flasks, ultra-low evacuated in attractive blue stove-enameled tough steel outer container.

Product Image-HEAT120734

Reagent reservoir chillers

Supplier: HEATHROW
Description: These reagent reservoir chillers are the ice-free, non-toxic way to extend the working period and preserve integrity for temperature sensitive reagents. They are made from sonic welded, engineered PP that ensures a leak free design.

Image Unavailable-BACE4026865.0025

AC1NUZLU (synthetic)

Supplier: BACHEM BIOCHEMICA
Description: zVAD-FMK inhibited apoptosis induced by diverse stimuli. Preincubation of cells with this caspase-1 (ICE) inhibitor (50 µM) almost completely inhibited the formation of large kilobase-pair fragments of DNA, a characteristic biochemical change associated with apoptosis.

Image Unavailable-ICNA0219484801

Sodium chloride ≥99.5%, white crystalline powder for molecular biology

Supplier: MP Biomedicals
Description: Sodium chloride is a commonly used chemical which is found widely in nature. It is considered to be an essential nutrient. Excess amounts of sodium chloride can destroy electrolyte balance and cause death in most animals, including humans.
Sodium chloride is used in a wide variety of biochemical applications, including intravenous fluids (normal saline is 0.9% w/v in water 10), density gradients 3,6, a diluent to increase ionic strength in buffers or culture media and in salt-out procedures in the isolation of DNA. It has also been used in high concentrations for preservation of foods since bacteria cannot grow in high salt conditions. A salt-ice mixture in the ratio of approximately 33 g sodium chloride to 100 g ice (at -1°C) will drop in temperature to as low as -21°C, depending on the rate of stirring and the size of the ice chunks.

Image Unavailable-ENZOALX850236KI01

Caspase inhibitor set

Catalog Number: (ENZOALX850236KI01)
Supplier: Enzo Life Sciences
Description: Synthetic peptides that irreversibly inhibit the activity of each of the caspase-family proteases. YVAD is the recognition sequence for caspase-1/ICE, DEVD is the recognition sequence for caspase-3/CPP32, VEID is the recognition sequence for caspase-6/Mch2, IETD is the recognition sequence for caspase-8/ FLICE, and VAD is the recognition sequence for a caspase(s) that functions upstream of most other caspases.   
UOM: 1 * 1 SET
Product Image-ENZOBMLCM1100100

Bafilamycin A1 ≥95% (by HPLC, TLC)

Catalog Number: (ENZOBMLCM1100100)
Supplier: Enzo Life Sciences
Description: Macrolide antibiotic that acts as a potent and selective inhibitor of vacuolar-type H<sup>+</sup>-ATPase (V-type) (IC<sub>50</sub>=004 - 0.4 nmol/mg). Valuable tool for distinguishing among different types of ATPases. Inhibitor of endosomal acidification. Blocks lysosomal cholesterol trafficking in macrophages. Blocks pH regulation in brain cells.
UOM: 1 * 100 µG
Product Image-GAINWL-012-1P

Cryogenic warning labels

Supplier: GA
Description: Cryogenic warning labels for storage in liquid nitrogen, freezers, dry ice and other harsh environments. It is resistant to multiple freeze-thaw cycles, boiling water, UV rays, sterilization by gamma irradiation, deep-freeze and harsh lab environments.

Product Image-GAINBOC-27C3-1WH

Permanent Deep Freeze Cover Up Labels for Thermal Transfer Printers

Supplier: GA
Description: These freezer grade blackout labels are designed to conceal any already existing information or labels. Can be used to re-label cryo vials, microtubes, and freezer boxes stored in ultra-low temperature freezers (−80 °C) or transported in dry ice.

Image Unavailable-324410-10

Dynasore ≥98% (by HPLC), Millipore®

Catalog Number: (324410-10)
Supplier: Merck Millipore (Calbiochem‎)
Description: Dynasore, also known as Dynamin inhibitor I, is a cell-permeable semicarbazone compound that inhibits the GTPase activity of dynamin1/2 (IC<sub>50</sub> ~15 µM) and Drp1. It has no significant effect against two other small GTPases, MxA and Cdc42.
UOM: 1 * 10 mg
Image Unavailable-BOSSBS-11132R-HRP

Anti-LMNB2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-11132R-HRP)
Supplier: Bioss
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11132R

Anti-LMNB2 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-11132R)
Supplier: Bioss
Description: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
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