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Catalog Number: (115-2426)
Supplier: Deb-STOKO
Description: Fragrant foam hand wash with a rich blend of pure essential oils of cedarwood and patchouli. It removes general dirt and grime. Suitable for all over body use.
UOM: 1 * 6 items


Supplier: Deb-STOKO
Description: Specialist pre-work skin protection cream against stubborn, non water-soluble dirt such as oils, paints, graphite, metallic dust, adhesives and water-insoluble workplace substances. Suitable for use on hands and body. For areas where gloves are not worn.

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Catalog Number: (613-2795)
Supplier: EPPENDORF
Description: Electronic pipetting doesn't come any more advanced than the Easypet 3 from Eppendorf. Designed to work with Eppendorf serological pipettes, you get complete speed control and utmost precision in an extremely light and well-balanced body that fits comfortably in your hand, for fatigue-free pipetting.
UOM: 1 * 1 items

Environmentally Preferable


Supplier: Corning
Description: These high precision digital pipettes combine all the requirements of modern pipettes. Their body shape is equally comfortable in small and large hands, with design innovations such as two ejector buttons providing the user with the ability to optimise personal ergonomics. Constructed from durable PP/PVDF they are noticeably lighter in weight than many competitive models.

Supplier: GLASS PRECISION ENGINEERING
Description: These homogenisers combine a conical and a cylindrical surface giving two separate areas, one for initial grinding and a second for final homogenisation.

Catalog Number: (115-3452)
Supplier: GOJO Industries - Europe Ltd
Description: Luxurious lotion soap.
UOM: 1 * 8 items

Catalog Number: (ENZOALX804510C100)
Supplier: ENZO LIFE SCIENCES
Description: The GST Family
Glutathione S-transferases (GSTs) are a large multigen family of multifunctional enzymes, which play an important role in detoxification of potentially genotoxic chemicals, by catalyzing the conjugation of glutathione to a large number of hydrophobic and electrophilic compounds, including carcinogens. They also bind to a variety of nonsubstrate ligands. The GSTs are widely distributed in mammalian species and can be grouped into four classes, based on their biochemical, immunological and structural properties: alpha, mu, pi and theta.

GSTs are dimeric, mainly cytosolic, enzymes that have extensive ligand binding properties in addition to their catalytic role in detoxification. A separate microsomal class of GSTs exists which is quite distinct from the cytosolic GSTs, and is designated as "membrane-associated proteins in eicosanoid and glutathione metabolism" (MAPEG). The N-terminal region tends to be better conserved within classes as it includes an important part of the active site.GSTs are believed to play a role in cancer prevention, as the electrophilic compounds that are conjugated to glutathione could otherwise react with and modify cellular components such as DNA, thereby initiating carcinogenesis. On the other hand, GSTs might detoxify chemotherapeutic drugs in cancer cells, thus contributing to drug resistance.
In summary, GSTs are a group of enzymes which are centrally involved in drug metabolism and detoxification. Because of their role in detoxification, they have been implicated in drug sensitivity and resistance. They may also influence mutagenesis and carcinogenesis and thus, increased GST activity may become a useful cancer marker.
Since many GST genes are polymorphic, there has been considerable interest in determining whether particular allelic variants are also associated with an increase of risk for certain diseases.

Glutathione S-transferase-Pi
The GST-Pi class (phase II detoxification enzymes) is the most abundant of the human glutathione S-transferases family, a major group of detoxification enzymes and widely distributed in the human body.
In normal human tissues, the enzymes protect cells against reactions with glutathione and reactive oxygen species by reducing organic hydroperoxides via gluthathione peroxidase activity.
The role of GST-Pi in tumor growth and progression is less well known. It is reported to be variably expressed in breast cancer and is associated with estrogen receptor levels expressed by the tumor. Down-regulation of GST-Pi activity in a study done on a T cell line appears to favor apoptosis and inhibition of GST-Pi function induces apoptosis in rat hepatoma cells.
The importance in cancer research is clear, as GST-Pi has been implicated in protection against apoptosis and also suggested to have a role in jun kinase inhibition.
The majority of human tumor cell lines express significant amounts of class pi GST, which is why it is being investigated as a potential marker for various types of cancer. GST-Pi is thought to be associated with increased resistance to anticancer drugs. GST-Pi expression is under investigation as a prognostic indicator for resistance to chemotherapy and a marker of treatment resistance.
UOM: 1 * 100 µG

New Product


Supplier: VWR Collection
Description: These mats are made of low density polyurethane providing an ergonomic, anti-fatigue profile. Bubble mats are designed for dry, non critical environments, reducing trip hazards, body aches, quality issues and sick leave. The smooth, flat mats are ideal for dry, non critical environments where sitting and standing work areas are combined, or where carts or trolleys must be used.

Catalog Number: (43884-10MG)
Supplier: Merck
Description: 2-(4-tert-Butylbenzyl)propionaldehyde is categorised under the synthetic fragrance class of compounds widely utilised in consumer products such as perfumes, after shave lotions, cosmetics and more.
UOM: 1 * 10 mg


Catalog Number: (PRSI56-680)
Supplier: ProSci Inc.
Description: A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly. It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus. Its compartmentalized phosphorylation cycle may also contribute to the directionality of export. Binds strongly to m7G-capped U1 and U5 small nuclear RNAs (snRNAs) in a sequence-unspecific manner and phosphorylation-independent manner (By similarity). Plays also a role in the biogenesis of U3 small nucleolar RNA (snoRNA). Involved in the U3 snoRNA transport from nucleoplasm to Cajal bodies. Binds strongly to m7G-capped U3, U8 and U13 precursor snoRNAs and weakly to trimethylated (TMG)-capped U3, U8 and U13 snoRNAs. Binds also to telomerase RNA.
UOM: 1 * 400 µl

New Product


Catalog Number: (113-9611)
Supplier: Portwest
Description: Technical work jacket made with two-faced premium fabric, which gives a softer feel inside and out, as well as offering excellent protection against the weather. In cold conditions, the kangaroo pockets on the front of the fleece are ideal for keeping hands warm, the hood helps in the rain, and the wicking fabric draws moisture away from the body to keep it dry, warm, and comfortable.
UOM: 1 * 1 items


Supplier: Thermo Fisher Scientific
Description: Isododecane, mixture of isomer acts as a reaction medium used for polymerisation reactions. It is also useful as an emollient and solvent in skin care products due to its high spreadability, low viscosity and density. It is commonly used in anti-aging serums and also useful in many different cosmetic items like eyeliner, hair care, hair sprays, perfume, conditioners and lotions.

New Product

Catalog Number: (ERGOEFB-LIGHTGREY)
Supplier: ERGOMAT
Description: The ESD mats Ergomat® EFB and EFS Complete are made from pure polyurethane and are designed to increase comfort while reducing trip hazards and body pain. These mats are ideal for areas that combine sitting and standing or where static electricity control is a must. The smooth version is ideal for areas where trolleys and carts are used.
UOM: 1 * 1 items


Supplier: UPCHURCH SCIENTIFIC
Description: <B>PEEK Zero Dead Volume unions:</B> Zero Dead Volume (ZDV) unions come complete with two F-300 fingertight fittings for ¹/₁₆" Ext.Ø tubing and are pressure rated to 5000 psi (344 bar).

Supplier: ERGOMAT
Description: The anti-static Ergomat® AFS Complete is made of pure polyurethane and is designed to increase comfort while reducing trip hazards and body pain. This mat is for all dry and damp areas where flame retardant and anti-static material is important. Great chemical resistancy for where chemical or oil spillage may occur. The smooth version is ideal for areas where trolleys and carts are used.

Supplier: MP Biomedicals
Description: Cetyl alcohol is used in the cosmetic industry as an opacifier in shampoos, or as an emollient, emulsifier or thickening agent in the manufacture of skin creams and lotions. It is also employed as a lubricant for nuts and bolts.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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