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You Searched For: HAT+activator,+CTPB


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Laboratory Glassware Washers, Large Capacity, PLW 8616

Supplier: MIELE
Description: The PLW 8616 laboratory washer can accommodate 216 laboratory flasks, 588 vials, or 294 pipettes. The large glassware washer is flexible and simple to use, it has modular load carriers and SimpleLoad system. This efficient unit has a double door, 900 mm wide, a usable capacity of 351 litres. PLW 8616 provides reliable results, high pump performance with a variable-speed pump and features spray arm monitoring and a conductivity meter.

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First Base™ 3 Bump Caps

Supplier: 3M
Description: The 3M™ First Base™ 3 series of bump caps are designed to provide the wearer with protection in a wide range of low risk applications.

New Product

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Chin strap, PA48

Catalog Number: (PRTWPA48BKR)
Supplier: Portwest
Description: Four points chin strap suitable for Endurance helmets.
UOM: 1 * 5 items
Product Image-111-1522

Safety helmets, Concept Roofer

Supplier: CENTURION SAFETY PRODUCTS
Description: The Concept Roofer is a light, strong and comfortable helmet made from ABS.

Product Image-111-0903

Accessories for centurion helmets, Connect®

Supplier: CENTURION SAFETY PRODUCTS
Description: Hinged and individually adjustable face shield attachment of polyetherimide (PEI). For use in hot factories.

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Safety helmets, Expertbase, PW50

Supplier: Portwest
Description: High-density polypropylene shell helmet, Four points plastic suspension harness. Buckle adjustable size 55 to 62 cm.

Image Unavailable-PRTWPS55WHR

Safety helmet, Endurance, PS55

Catalog Number: (PRTWPS55WHR)
Supplier: Portwest
Description: Endurance vented ABS shell helmet without retractable visor.
UOM: 1 * 1 items
Product Image-111-0899

Accessories for centurion helmets

Supplier: CENTURION SAFETY PRODUCTS
Description: Sweatband S31P, PVC, for Concept helmet, CenturION™

Product Image-PRTWHA10BKR

Fleece hat, with Insulatex™ lining, HA10

Supplier: Portwest
Description: This classic fleece hat made of 100% polyester fleece is ideal for outdoor use.

Product Image-EDVO222

Transformation with blue and green fluorescent proteins

Catalog Number: (EDVO222)
Supplier: EDVOTEK
Description: The Green Fluorescent Protein (GFP) from the jellyfish <i>Aequorea victoria</i> is used extensively in all areas of science. Many organisms have been transformed with the GFP gene, the gene responsible for bioluminescence in jellyfish. It has proven to be so useful that scientists have mutated it to produce Blue Fluorescent Protein (BFP). In this simple experiment, students transform bacteria either by GFP, BFP or both.
UOM: 1 * 1 items

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Product Image-PRTWPW54WHR

Safety helmet, Endurance Plus, PW54

Supplier: Portwest
Description: This fully certified ABS helmet features molten metal protection with a retractable visor.

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Safety helmets, Diamond V

Supplier: DELTA PLUS
Description: Industrial protective / construction helmet made of ABS in baseball helmet style. With polyamide interior, textile straps with 8-point suspension and terry sweatband.

Product Image-PRTWPW50RER

Safety helmet, Endurance, PW50

Supplier: Portwest
Description: The helmet made from impact resistant polypropylene shell offers exceptional protection.

Image Unavailable-BOSSBS-3390R-A750

Anti-SATB1 Ser47 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-3390R-A750)
Supplier: Bioss
Description: Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes (e.g. PML at the MHC-I locus) and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes. Required for the switching of foetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organisation and nuclear architecture during apoptosis. Interacts with the unique region (UR) of cytomegalovirus (CMV). Alu-like motifs and SATB1-binding sites provide a unique chromatin context which seems preferentially targeted by the HIV-1 integration machinery. Moreover, HIV-1 Tat may overcome SATB1-mediated repression of IL2 and IL2RA (interleukin) in T-cells by binding to the same domain than HDAC1. Delineates specific epigenetic modifications at target gene loci, directly up-regulating metastasis-associated genes while down-regulating tumor-suppressor genes. Reprograms chromatin organisation and the transcription profiles of breast tumors to promote growth and metastasis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3390R-A647

Anti-SATB1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-3390R-A647)
Supplier: Bioss
Description: Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes (e.g. PML at the MHC-I locus) and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes. Required for the switching of fetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organization and nuclear architecture during apoptosis. Interacts with the unique region (UR) of cytomegalovirus (CMV). Alu-like motifs and SATB1-binding sites provide a unique chromatin context which seems preferentially targeted by the HIV-1 integration machinery. Moreover, HIV-1 Tat may overcome SATB1-mediated repression of IL2 and IL2RA (interleukin) in T-cells by binding to the same domain than HDAC1. Delineates specific epigenetic modifications at target gene loci, directly up-regulating metastasis-associated genes while down-regulating tumor-suppressor genes. Reprograms chromatin organization and the transcription profiles of breast tumors to promote growth and metastasis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3390R-CY5

Anti-SATB1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-3390R-CY5)
Supplier: Bioss
Description: Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes (e.g. PML at the MHC-I locus) and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes. Required for the switching of fetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organization and nuclear architecture during apoptosis. Interacts with the unique region (UR) of cytomegalovirus (CMV). Alu-like motifs and SATB1-binding sites provide a unique chromatin context which seems preferentially targeted by the HIV-1 integration machinery. Moreover, HIV-1 Tat may overcome SATB1-mediated repression of IL2 and IL2RA (interleukin) in T-cells by binding to the same domain than HDAC1. Delineates specific epigenetic modifications at target gene loci, directly up-regulating metastasis-associated genes while down-regulating tumor-suppressor genes. Reprograms chromatin organization and the transcription profiles of breast tumors to promote growth and metastasis.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
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