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Product Image-TNB-6600-KIT

Anti-BrdU Mouse Monoclonal Antibody (FITC) [clone: PRB-1]

Catalog Number: (TNB-6600-KIT)
Supplier: Tonbo Biosciences
Description: The fragmentation of genomic DNA by cellular nucleases during the later stages of apoptosis is also one of the most easily measured features of apoptotic cells. Nuclease activity generates DNA fragments ranging from ~300 bp to 50 bp in length, resulting in a typical DNA ‘laddering’ appearance when analyzed by agarose gel electrophoresis. These fragments have exposed 3’-hydroxyl (OH) ends which can be labeled with bromolated deoxyuridine triphosphates (Br-dUTP). An enzyme, terminal deoxynucleotidyl transferase (TdT), is used to catalyze the template-independent addition of Br-dUTP to the 3’-OH ends of double or single stranded DNA. This method is often called TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labeling) or end labeling. Sites where the Br-dUTP is incorporated can then be detected with an antibody specific to BrdU. With the APO-BrdUTM Kit cells are first labeled with Br-dUTP, and then sites of incorporation are detected through staining with a FITC anti-BrdU antibody. Samples can then be analyzed via flow cytometry. Samples that are apoptotic will stain brightly with the anti-BrdU antibody due to the substantial number of exposed 3’-OH sites, while cells that are non-apoptotic will not have incorporated significant amounts of Br-dUTP and will stain dimly. The APO-BrdU Kit is shipped in one container and consists of two packages. Upon arrival one should be stored at 2-8°C and the other at -20°C.
UOM: 1 * 50 Tests
Product Image-SAMP1230C-1500

Samplers, U-D Master

Supplier: Sampling Systems
Description: U-D Master is designed for sampling free flowing powders. By simply changing the sample insert cells, different volumes can be sampled.

Product Image-STMC100-0354

MSC Characterization Antibody Panel

Catalog Number: (STMC100-0354)
Supplier: STEMCELL Technologies
Description: Multi-color flow cytometry kit for characterization of human mesenchymal stromal cells
UOM: 1 * 1 items

Market Source Item This is a MarketSource item. Additional charges may apply

Product Image-AATB21704

Dextran, M.W. 150,000 FITC labelled

Catalog Number: (AATB21704)
Supplier: AAT BIOQUEST
Description: FITC-labeled dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination.
UOM: 1 * 25 mg
Product Image-AATB21706

Dextran, M.W. 20,000 TRITC-labeled

Catalog Number: (AATB21706)
Supplier: AAT BIOQUEST
Description: TRITC-labeled dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination.
UOM: 1 * 25 mg
Product Image-13-0871-T100

Ghost Dye™ Red 710

Supplier: Tonbo Biosciences
Description: Ghost Dye Red 710 is an amine reactive viability dye, that can be used to discriminate viable from non-viable mammalian cells in flow cytometry applications.

Image Unavailable-BOSSBS-7689R-A350

Anti-KCNMB1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-7689R-A350)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7689R-CY3

Anti-KCNMB1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-7689R-CY3)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7689R-CY5

Anti-KCNMB1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-7689R-CY5)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7689R-CY7

Anti-KCNMB1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-7689R-CY7)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7689R-CY5.5

Anti-KCNMB1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-7689R-CY5.5)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Product Image-40085-T

NucSpot® Far-Red 1000X in DMSO

Supplier: Biotium
Description: NucSpot® Far-Red was designed to be an improved alternative to 7-AAD showing less bleed-through fluorescence in the PE-Texas Red® channel. Ideal for selective detection of dead cells by flow cytometry.

Image Unavailable-PEAK3304886

Collision Gas Add-On Nitrogen Generator

Catalog Number: (PEAK3304886)
Supplier: PEAK SCIENTIFIC
Description: The Collision Gas Add-On has been designed to serve a number of generators, and supplies ultra high purity nitrogen to the collision cell at a flow of up to 200 cc/min.
UOM: 1 * 1 items

New Product


Product Image-STMC100-1451

Intracellular Permeabilisation Buffer (10X)

Catalog Number: (STMC100-1451)
Supplier: STEMCELL Technologies
Description: Ideal for the permeabilisation of fixed cells during labeling of cytokines and other cytoplasmic antigens. Intracellular Permeabilisation Buffer (10X) is uniquely formulated for optimal resolution and to reduce background and is suitable for use with fluorochrome-conjugated antibodies for flow cytometry.
UOM: 1 * 150 mL

New Product

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-ORIGTA591090

Anti-CD20 IgG2a Monoclonal Antibody [clone: 743AB71]

Catalog Number: (ORIGTA591090)
Supplier: OriGene
Description: Recommended Dilutions: Use at 0.1-1ug/ml. Flow Cytometry , Direct cell killing
UOM: 1 * 100 µl
Product Image-AATB22325

Bucculite™ Flow Cytometric XdU Cell Proliferation Assay Kit

Catalog Number: (AATB22325)
Supplier: AAT BIOQUEST
Description: It is sensitive and might be used for measuring active DNA synthesis at single-cell level.
UOM: 1 * 100 Tests
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
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Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
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