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Product Image-AATB15296

Cell Meter™ Intracellular NADH/NADPH Flow Cytometric Analysis Kit *Deep Red Fluorescence*

Catalog Number: (AATB15296)
Supplier: AAT BIOQUEST
Description: The detection of intracellular dihydronicotinamide adenine dinucleotide NADH and its phosphate ester NADPH is important for disease diagnostics and drug discovery.
UOM: 1 * 100 Tests
Product Image-AATB21704

Dextran, M.W. 150,000 FITC labelled

Catalog Number: (AATB21704)
Supplier: AAT BIOQUEST
Description: FITC-labeled dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination.
UOM: 1 * 25 mg
Product Image-AATB21706

Dextran, M.W. 20,000 TRITC-labeled

Catalog Number: (AATB21706)
Supplier: AAT BIOQUEST
Description: TRITC-labeled dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination.
UOM: 1 * 25 mg
Product Image-662-0815

Replacement modules for Orion™ ISE electrodes

Supplier: Thermo Orion
Description: Plastic membrane replacement module for Nitrate half-cell electrode 9307BNWP, Sure-Flow™ junction

Image Unavailable-BOSSBS-11332R-CY7

Anti-CNG channel beta 1/truncated GARP Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-11332R-CY7)
Supplier: Bioss
Description: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11332R-CY5

Anti-CNG channel beta 1/truncated GARP Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-11332R-CY5)
Supplier: Bioss
Description: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11332R-A488

Anti-CNG channel beta 1/truncated GARP Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-11332R-A488)
Supplier: Bioss
Description: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
UOM: 1 * 100 µl
Image Unavailable-AATB22426

Cell Navigator™ Flow Cytometric Exosome Staining Kit

Catalog Number: (AATB22426)
Supplier: AAT BIOQUEST
Description: Designed for consistent and dependable results. The Cell Navigator™ Flow Cytometric Exosome Staining Kit addresses these challenges by enabling the detection of CD9-positive exosomes in purified or bead-bound samples.
UOM: 1 * 100 Tests

New Product


Image Unavailable-29-0609-48

Pump tubing for AKTA flux

Catalog Number: (29-0609-48)
Supplier: Cytiva
Description: Pump tubing for AKTA flux, AKTA flux is a versatile cross flow filtration system for sample concentration and diafiltration (buffer exchange) as well as cell harvest and clarification.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-7689R

Anti-KCNMB1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-7689R)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7689R-FITC

Anti-KCNMB1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-7689R-FITC)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11332R

Anti-CNG channel beta 1/truncated GARP Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-11332R)
Supplier: Bioss
Description: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11332R-CY3

Anti-CNG channel beta 1/truncated GARP Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11332R-CY3)
Supplier: Bioss
Description: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
UOM: 1 * 100 µl
Product Image-HEWLG1375-87321

Capillaries for LC systems

Supplier: Agilent
Description: Stainless steel capillaries are made of flexible stainless steel (0,6 mm OD) with ¹/₁₆" OD tubing at both ends to accept standard fittings.

Product Image-AATB21700

Native Dextran (from Eukaryotic cells), FITC (Fluorescein Isothiocyanate)

Catalog Number: (AATB21700)
Supplier: AAT BIOQUEST
Description: FITC-labeled dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination.
UOM: 1 * 25 mg
Product Image-HEWL5063-6522

Accessories for UV-Vis certified calibration standards

Supplier: Agilent
Description: Accessory for Colour measurement, OQ/PV hardware kit for UV-VIS. Includes 2 flow cells, cell passivating fluid, tubing kit, MCT adjustment hook, temperature sensor support, syringes, OQ/PV manual

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
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