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Catalog Number: (BOSSBS-11332R-CY3)
Supplier: Bioss
Description: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
UOM: 1 * 100 µl


Catalog Number: (AATB16351)
Supplier: AAT BIOQUEST
Description: Nitric oxide (NO) is an important biological regulator involved in numbers of physiological and pathological processes.
UOM: 1 * 100 Tests


Catalog Number: (AATB22804)
Supplier: AAT BIOQUEST
Description: This particular kit is designed to detect cell apoptosis by measuring the loss of the mitochondrial membrane potential(MMP).
UOM: 1 * 100 Tests


Catalog Number: (STMC100-0923)
Supplier: STEMCELL Technologies
Description: For detection of active caspase-3 in mammalian cells undergoing apoptosis - 100 tests.
UOM: 1 * 100 items

Market Source Item This is a MarketSource item. Additional charges may apply

Catalog Number: (BOSSBS-9847R-A750)
Supplier: Bioss
Description: Primary canalicular bile undergoes a process of fluidization and alkalinization along the biliary tract that is influenced by several factors, including hormones, innervation/neuropeptides and biliary constituents. The excretion of bicarbonate at both the canaliculi and the bile ducts is an important contributor to the generation of bile-salt independent flow. Bicarbonate is secreted from hepatocytes and cholangiocytes through parallel mechanisms, which involve chloride efflux through activation of chloride channels and further bicarbonate secretion via AE2 (also designated SLC4A2)-mediated chloride/bicarbonate exchange. The AE2 protein regulates pH, chloride concentration, cell volume and transepithelial ion transport in many tissues. Gene silencing of AE2 causes a marked inhibition of unstimulated and secretin-stimulated chloride/bicarbonate exchange, which maintains the bile acid pool that is crucial for secretin to induce bicarbonate-rich choleresis.
UOM: 1 * 100 µl


Catalog Number: (STMC100-0924)
Supplier: STEMCELL Technologies
Description: For detection of active caspase-3 in mammalian cells undergoing apoptosis.
UOM: 1 * 100 µG

Market Source Item This is a MarketSource item. Additional charges may apply

Supplier: PROMOCELL
Description: Pericytes are multipotent mesenchymal-like cells found in association with small blood vessel walls and are important for angiogenesis, the structural integrity of the microvasculature and blood flow regulation. However, they can also develop into malignant tumours called hemangiopericytomas.

Catalog Number: (AATB16317)
Supplier: AAT BIOQUEST
Description: Peroxynitrite (ONOO-) is a strong oxidizing species and a highly active nitrating agent.
UOM: 1 * 100 Tests


Supplier: Bel-Art Products, a Part of SP
Description: Scienceware® Flowmi™ cell strainers provide fast and efficient filtering of small volume samples (up to 1000 µl) prior to FLOW or FACS analysis. Patent pending.

Supplier: AAT BIOQUEST
Description: Flow cytometry combined with fluorescence staining is a powerful tool to analyse heterogeneous cell populations.

Catalog Number: (BOSSBS-11332R-A350)
Supplier: Bioss
Description: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
UOM: 1 * 100 µl


Catalog Number: (AATB22838)
Supplier: AAT BIOQUEST
Description: Annexin V may be conjugated to fluorochromes including PE.
UOM: 1 * 100 Tests


Catalog Number: (AATB16356)
Supplier: AAT BIOQUEST
Description: Nitric oxide (NO) is an important biological regulator involved in numbers of physiological and pathological processes.
UOM: 1 * 100 Tests


Supplier: Mettler - Toledo
Description: A glass-body, combination pH electrode with SteadyForce™ and S7 screw head for inline measurements in flow-through cell 611.

Catalog Number: (662-0766)
Supplier: Thermo Orion
Description: This electrode is a sleeve-type refillable Ag/AgCl (silver/silver chloride) reference electrode with an outer chamber that isolates the inner reference element and filling solution from the sample. This electrode is designed for precision measurements with ion selective half-cell electrodes and pH half-cell electrodes.
UOM: 1 * 1 items

Catalog Number: (AATB22426)
Supplier: AAT BIOQUEST
Description: Designed for consistent and dependable results. The Cell Navigator™ Flow Cytometric Exosome Staining Kit addresses these challenges by enabling the detection of CD9-positive exosomes in purified or bead-bound samples.
UOM: 1 * 100 Tests

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
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