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Image Unavailable-BOSSBS-13390R-CY7

Anti-GLUD2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-13390R-CY7)
Supplier: Bioss
Description: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.
UOM: 1 * 100 µl
Product Image-EDVO274

Experimentation kits, in search of the 'Kissing Disease'

Catalog Number: (EDVO274)
Supplier: EDVOTEK
Description: Infectious mononucleosis is commonly known as the 'kissing disease'. The causative agent is Epstein-Barr virus (EBV), which can be transmitted through saliva during kissing. In this experiment, students search for the presence of EBV using the ELISA reaction to detect specific viral proteins.
UOM: 1 * 1 items

SDS


Product Image-EDVO275

Experimentation kits, simulation of HIV detection by western blot (agarose-based)

Catalog Number: (EDVO275)
Supplier: EDVOTEK
Description: The second assay used to confirm a positive HIV ELISA result is the Western blot. Using this kit, students separate protein samples from hypothetical patients on agarose gels. The proteins are then transferred to a membrane and simulated HIV proteins are detected.
UOM: 1 * 1 items
Product Image-763-0009

Kits: the case of the invisible bands, Ready-to-Load™

Catalog Number: (763-0009)
Supplier: EDVOTEK
Description: Experiment using fluorescence and electrophoresis to solve the mystery of the invisible bands.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-9051R-A680

Anti-TRPM4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-9051R-A680)
Supplier: Bioss
Description: Calcium-activated non selective (CAN) cation channel that mediates membrane depolarisation. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarise the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload. Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localisation. Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9051R-A750

Anti-TRPM4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-9051R-A750)
Supplier: Bioss
Description: Calcium-activated non selective (CAN) cation channel that mediates membrane depolarisation. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarise the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload. Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localisation. Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.
UOM: 1 * 100 µl
Product Image-DIDAPOD013210

He-Ne laser

Supplier: DIDALAB
Description: High quality professional gas laser, Class II

Product Image-216-0428

Pneumatic trough, pp, Nalgene®

Catalog Number: (216-0428)
Supplier: Thermo Fisher Scientific
Description: Replace metal-type troughs with the polypropylene pneumatic trough.
UOM: 1 * 1 items

Environmentally Preferable


Product Image-DIDAPOD060110

High quality prismatic optical bench

Supplier: DIDALAB
Description: Triangular, cast aluminium optical bench

Product Image-552-0288

TLC education advanced kit, micro-set F2

Catalog Number: (552-0288)
Supplier: MACHEREY-NAGEL
Description: Advanced kit for science education.
UOM: 1 * 1 KIT
Product Image-EDVO986

Experimentation kits, analysis and comparision of mammalian cell types

Catalog Number: (EDVO986)
Supplier: EDVOTEK
Description: Observe the differences between mammalian cell types and how these cells funciton. Cells are fixed on microscope slides and students stain the cells on the slide to view morphological characteristics of the cell types. These cells are very safe for classroom use.
UOM: 1 * 1 items
Product Image-761-0139

Nicotine dependence chart

Catalog Number: (761-0139)
Supplier: 3B Scientific
Description: Over 30% of the world's population uses tobacco products, and 90% of that is from cigarettes. The physical effects of nicotine and the diseases it can cause, including cancer, are detailed on this anatomical poster. For such a wide spread practice education is important and this anatomy poster can help do that. This thickly laminated anatomical chart is printed on premium glossy (200 g) UV resistant paper and comes with two sided lamination (125 µm, 5,0 mil) and metal eyelets to make the chart easy to display.
UOM: 1 * 1 items

Market Source Item This is a MarketSource item. Additional charges may apply

Product Image-DIDAPOD013136

Diode lasers, class II

Supplier: DIDALAB
Description: Educational Materials, Optics, Application: Physics, Diode laser, red, Class II

Product Image-552-0287

TLC education advanced kit, micro set F1

Catalog Number: (552-0287)
Supplier: MACHEREY-NAGEL
Description: Advanced kit for science education.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-13390R-A488

Anti-GLUD2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-13390R-A488)
Supplier: Bioss
Description: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13390R-A350

Anti-GLUD2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-13390R-A350)
Supplier: Bioss
Description: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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