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Image Unavailable-BOSSBS-9688R-CY7

Anti-BLNK Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-9688R-CY7)
Supplier: Bioss
Description: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9687R-CY5

Anti-BLNK Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-9687R-CY5)
Supplier: Bioss
Description: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].
UOM: 1 * 100 µl

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Product Image-LENZ05288004

Distilling receivers, Bernauer

Supplier: Lenz Laborglas GmbH & CO.KG
Description: DURAN®, borosilicate glass, clear.

Image Unavailable-LENZ05434000

Apparatus - Antonacopoulos

Supplier: Lenz Laborglas GmbH & CO.KG
Description: DURAN®, Borosilicate glass.

Product Image-BOHLB303-02

Distilling links, BOLA

Catalog Number: (BOHLB303-02)
Supplier: Bohlender
Description: PTFE, white.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-11024R

Anti-DNAI1/2 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-11024R)
Supplier: Bioss
Description: The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11024R-CY5

Anti-DNAI1/2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-11024R-CY5)
Supplier: Bioss
Description: The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11024R-CY3

Anti-DNAI1/2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11024R-CY3)
Supplier: Bioss
Description: The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11975R-CY5

Anti-CACYBP Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-11975R-CY5)
Supplier: Bioss
Description: CacyBP is a 228 amino acid protein encoded by the human gene CACYBP. CacyBP is primarily a nuclear protein that contains one CS domain and one SGS domain. CacyBP is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in ubiquitin E3 complexes. It also participates in the ubiquitin-mediated degradation of b-catenin. CacyBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on b-catenin protein expression and transcriptional activation of TCF/LEF.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12862R-CY7

Anti-CTXB Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-12862R-CY7)
Supplier: Bioss
Description: The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11024R-A555

Anti-DNAI1/2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-11024R-A555)
Supplier: Bioss
Description: The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11975R-FITC

Anti-CACYBP Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-11975R-FITC)
Supplier: Bioss
Description: CacyBP is a 228 amino acid protein encoded by the human gene CACYBP. CacyBP is primarily a nuclear protein that contains one CS domain and one SGS domain. CacyBP is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in ubiquitin E3 complexes. It also participates in the ubiquitin-mediated degradation of b-catenin. CacyBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on b-catenin protein expression and transcriptional activation of TCF/LEF.
UOM: 1 * 100 µl
Product Image-LENZ05117304

Distillation columns, Hempel

Supplier: Lenz Laborglas GmbH & CO.KG
Description: DURAN®, borosilicate glass, clear.

Image Unavailable-BOSSBS-3897R-A647

Anti-TXNIP Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-3897R-A647)
Supplier: Bioss
Description: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
UOM: 1 * 100 µl
Product Image-271-2542

Distributors for distilling receivers, Bredt

Supplier: Lenz Laborglas GmbH & CO.KG
Description: DURAN®, borosilicate glass.

Image Unavailable-BOSSBS-0282R-CY7

Anti-CCNC Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-0282R-CY7)
Supplier: Bioss
Description: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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