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GABAergic ligand library, Screen-Well®

Supplier: ENZO LIFE SCIENCES
Description: The GABAergic igands library contains 56 ligands including endogenous neurotransmitters, agonists, antagonists, and marketed drugs. The library is ideal for screening or identifying recombinant orphan G protein-coupled receptors, target validation, secondary screening, assay development, and other pharmacological applications. The GABAergics ligands plate is 1 plate of the larger neurotransmitter library which contains over 650 CNS receptor ligands.

Product Image-MILFMAMCS9610

MultiScreen® Multiscreen Well Culture Trays

Supplier: Merck
Description: HTS filter plates: Multiscreen HTS plates are specifically developed for high-throughput use with automated work stations. Rigid sidewalls improve handling and ample surfaces are provided for bar code labels. Wells are individually sealed to prevent incubation crosstalk and the underdrain is removable for access to the filters. Filter plates are available in 96- and 384-well platforms with a broad selection of membranes and plastics. Millipore's new Multiscreen HTS+ Hi flow filter plate design lessens non-specific binding and reduces variability in both background and signal intensities specifically for biochemical screening assays.

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Accessories for Millicell® 96-Well Cell Culture Insert Plates

Catalog Number: (MILFMACAC0RS5)
Supplier: Merck
Description: 96 well feeder/transport tray with lid, polystyrene
UOM: 1 * 5 items
Product Image-GREI781841_KIT

Accessories for magnetic 3D cell culturing, NanoShuttle™-PL

Supplier: Greiner Bio-One
Description: NanoShuttle™-PL is used to magnetise cells for 3D cell culturing. The cells can be aggregated with magnetic forces, either by levitation or printing, to form structurally and biologically representative 3D models <i>in vitro</i>.

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Protease inhibitor library, Screen-Well®

Supplier: ENZO LIFE SCIENCES
Description: The Screen-Well™ Protease Inhibitor Library includes 53 known protease inhibitors on a single 96-well plate. Inhibitors are supplied dissolved in DMSO at 10 mM and aliquoted into deep-well plates at either 100 or 500 microliters per well. The library includes inhibitors to a broad range of important proteases and is a convenient and cost-effective way to purchase a panel of protease inhibitors for chemical genomics, assay development, and other applications. It includes inhibitors of: Calpains, TPPII, Neutrophil Elastase, Cathepsins, DPPIV, Caspases, Granzyme B, gamma-Secretase, Furin, MMPs, ACE, Kallikrein, Proteasome, Aminopeptidase B, and many more.

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Hepatotoxicity library, Screen-Well®

Supplier: ENZO LIFE SCIENCES
Description: The Screen-Well® hepatotoxicity library is a focused collection of 238 compounds with defined and diverse hepatotoxicity, including steatosis, mitochondrial toxicity, Mallory body formation, cholestatic effects, and many more. A variety of structurally and mechanistically different compound classes are included, as well as nontoxic controls. The compounds are dissolved in DMSO at 10 mM and aliquoted into deep-well plates. The library is an essential tool for predictive toxicology screening and assay development.

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Adrenergic ligand library, Screen-Well®

Supplier: ENZO LIFE SCIENCES
Description: The adrenergic ligand library contains 84 ligands including endogenous neurotransmitters, agonists, antagonists, and marketed drugs. The library is ideal for screening or identifying recombinant orphan G protein-coupled receptors, target validation, secondary screening, assay development, and other pharmacological applications. The adrenergic ligand library is 1 plate of the larger neurotransmitter library which contains over 650 CNS receptor ligands.

Product Image-731-0315

VWR®, Sealing Film for Biological Cultures

Supplier: VWR Collection
Description: Rayon film with medical grade adhesive. Hydrophobic, porous film in sheeted roll format for sealing tissue culture plates, bio-blocks, and 96-well plates where gas exchange is necessary for cell or bacterial growth.

Product Image-BSENBEK-2222-2P

Glial cell line-derived neurotrophic factor (GDNF) Rapid™ ELISA kit: human

Supplier: Biosensis
Description: The Biosensis GDNF Rapid™ enzyme-linked immunosorbent assay (ELISA) kit is a sandwich ELISA that allows the quantification of GDNF in less than 4 hours in cell culture supernatants, cell lysates, and guinea pig serum only if used as directed.

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Phosphatase inhibitor library, Screen-Well®

Supplier: ENZO LIFE SCIENCES
Description: The Screen-Well™ Phosphatase Inhibitor Library contains 33 known phosphatase inhibitors of well-defined activity. Inhibitors are supplied dissolved in DMSO at 10 mM and aliquoted into deep-well plates at either 100 µl or 500 µl per well. The library is ideal for chemical genomics, assay development, and as a reference set for secondary screening. Includes inhibitors of these important phosphatases: Calcineurin(PP2B), JSP-1, PRL-1, CD45, PP1, PRL-3, CDC25, PP2A, PTEN, and many more.

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Hematopoietic library, Screen-Well®

Supplier: ENZO LIFE SCIENCES
Description: The Screen-Well® hematopoietic toxicity library is a focused collection of 115 compounds with defined and diverse hematopoietic toxicity, including myelosuppression, neutropenia, leukopenia, anaemia, and many more. A variety of structurally and mechanistically different compound classes are included, as well as nontoxic controls. The compounds are dissolved in DMSO at 10 mM and aliquoted into deep-well plates. The library is an essential tool for predictive toxicology screening and assay development.

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Wnt pathway library, Screen-Well®

Supplier: ENZO LIFE SCIENCES
Description: The Screen-Well® Wnt pathway library v 2.0 is a focused collection of 71 compounds with defined and diverse Wnt pathway activity, including activators and inhibitors of Wnts, Dishevelled, GSK-3β and other Wnt pathway kinases, TCF/β-catenin, DKK, LRP, Axin, Porcupine, and more. Compounds are dissolved in DMSO at 10 mM or 1 mM and aliquoted into deep-well plates at 100 or 500 µl per well. A variety of structurally and mechanistically different compound classes are included. A useful tool for studying the roles of pro- and anti-Wnt pathway molecules in cells as well as for use in<i> in vitro</i> applications.

Product Image-BSENBEK-2214-2P

NGF Rapid™ ELISA kit: rat

Supplier: Biosensis
Description: The Biosensis NGF Rapid™ enzyme-linked immunosorbent assay (ELISA) kit is a sandwich ELISA that allows the quantification of rat NGF in less than 3 hours in cell culture supernatants, serum, and brain extracts only if used as directed.

Product Image-BSENBEK-2217-2P

proBDNF Rapid™ ELISA Kit: Human, Mouse, Rat

Supplier: Biosensis
Description: The Biosensis proBDNF Rapid™ enzyme-linked immunosorbent assay (ELISA) kit is a sandwich ELISA that allows the specific, fast and reliable quantification of proBDNF in less than 4 hours in cell culture supernatants, cell lysates, serum, citrate-plasma and tissue extracts only if used as directed.

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Nephrotoxicity library, Screen-Well®

Catalog Number: (ENZOENZLIB1000100)
Supplier: ENZO LIFE SCIENCES
Description: The Screen-Well® nephrotoxicity library is a focused collection of 86 compounds with defined and diverse nephrotoxicity, including analgesic nephropathy, interstitial nephritis, glomerularopathy, proximal and distal tubulopathy, acute renal failure, chronic kidney disease, and more. A variety of structurally and mechanistically different compound classes are included, as well as nontoxic controls. Most of the compounds are dissolved in DMSO at 10 mM unless otherwise stated in the documentation provided with the library. Selected compounds are dissolved in DI water. All compounds are provided at 100 μl volumes in a 96-well plate. This library is an essential cost-effective tool for predictive toxicology screening and assay development.
UOM: 1 * 1 SET
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Epigenetics library, Screen-Well®

Supplier: ENZO LIFE SCIENCES
Description: The Screen-Well® epigenetics library contains 43 compounds with defined activity against enzymes which carry out epigenetic modification of lysine. It also includes DNA methylation inhibitors. Compounds are dissolved in DMSO at 10 mM and aliquoted into deep-well plates at 100 µl or 500 µl per well. The library is a useful tool for chemical genomics, assay development and other pharmacological applications. The library contains inhibitors of these important enzymes: HDACs, SIRTs, Lysine demethylases, HATs, Histone methyl transferases, DNA methyltransferases as well as SIRT activators. A variety of structurally and mechanistically different compound classes are included.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
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