You Searched For: Biotium

Supplier: Biotium

Description: Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD . It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.

Supplier: Biotium

Description: Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD . It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.

Catalog Number: (40021.)

Supplier: Biotium

Description: 5-Aminoallyl-UTP can be enzymatically incorporated into RNA for subsequent labeling with an amine-reactive fluorescent dye, biotin, or other hapten.

UOM: 1 * 100 µl

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Catalog Number: (51013.)

Supplier: Biotium

Description: 5-(and-6)-FAM (full name: 5-(and-6)-Carboxyfluorescein mixed isomer) has a pKa of 6.5 and can be used as a pH indicator. Its excitation spectrum and fluorescence response to pH are similar to those of BCECF. Carboxyfluorescein can also be used as a tracer dye. The dye is membrane-impermeant and can be loaded into cells by microinjection or scrape loading.

UOM: 1 * 100 mg

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Catalog Number: (90011.)

Supplier: Biotium

Description: 6-CR6G (full name: 6-Carboxyrhodamine 6G, hydrochloride, single isomer) is the free acid form of 6-carboxyrhodamine 6G single isomer.

UOM: 1 * 5 mg

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Catalog Number: (50040.)

Supplier: Biotium

Description: Membrane-impermeant calcium indicator that can be loaded into cells via microinjection or scrape loading.

UOM: 1 * 1 mg

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Supplier: Biotium

Description: MitoView™ dyes are fluorogenic mitochondrial stains for live cells. The dyes rapidly accumulate in mitochondria and can be imaged without washing. They are available with blue, green, far-red, and near-infrared fluorescence.

Supplier: Biotium

Description: Anti-IgG Goat Polyclonal Antibody (CF™ 555)

Catalog Number: (90001.)

Supplier: Biotium

Description: 5-(and-6)-Carboxyrhodamine 110, SE (5-(and-6)-Carboxyrhodamine 110, succinimidyl ester, mixed isomers), also known as Carboxyrhodamine 110-NHS, is a superior green fluorescent dye that readily reacts with primary or secondary amines. For many applications, the dye is preferred over 5-(and-6)-carboxyfluorescein succinimidyl ester (5(6)-FAM) or FITC because of its exceptional photostability and fluorescence insensitivity to pH (4-9).

UOM: 1 * 5 mg

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Catalog Number: (51019.)

Supplier: Biotium

Description: 5-Carboxyfluorescein has a pKa of 6.5 and can be used as a pH sensor. The excitation spectrum of the dye responds to pH similarly to that of BCECF. Carboxyfluorescein can also be used as a tracer dye. The dye is membrane-impermeant and can be loaded into cells by microinjection or scrape loading.

UOM: 1 * 100 mg

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Catalog Number: (40024.)

Supplier: Biotium

Description: BrdU (5-Bromo-2′-deoxyuridine) can be incorporated into DNA during cell division and subsequently detected by a BrdU antibody. The probe can be used to study cell-cycle kinetics.

UOM: 1 * 100 mg

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Catalog Number: (51014.)

Supplier: Biotium

Description: 5(6)-CFDA (full name: 5-(and-6)-Carboxyfluorescein diacetate) is membrane-permeant and thus can be loaded into cells via incubation.

UOM: 1 * 100 mg

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Catalog Number: (50010.)

Supplier: Biotium

Description: Fluo-3, pentaammonium is membrane-impermeant, but can be loaded into cells via microinjection or scrape loading.

UOM: 1 * 1 mg

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Supplier: Biotium

Description: Carbocyanine dyes with long hydrocarbon chains have low fluorescence in aqueous phase, but become highly fluorescent upon binding to lipid bilayers, making this class of dyes ideal for staining cell membranes. Carbocyanine dye membrane staining is very stable, with minimal dye transfer between cells. Dilinoleyl carbocynaine dyes have much faster lateral diffusion rates than regular carbocyanine dyes, which facilitates labelling of neurons in tissues.

Supplier: Biotium

Description: 4-Methylumbelliferyl phosphate

Supplier: Biotium

Description: β-glucuronidase substrates are easy to detect stains against the background of plant cells.