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Image Unavailable-BOSSBS-13545R-A555

Anti-GUCY1A2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-13545R-A555)
Supplier: Bioss
Description: Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13545R-FITC

Anti-GUCY1A2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-13545R-FITC)
Supplier: Bioss
Description: Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
UOM: 1 * 100 µl
Image Unavailable-APOSOR6978-1G

Methyl 3-hydroxy-4-(hydroxymethyl)benzoate

Catalog Number: (APOSOR6978-1G)
Supplier: Apollo Scientific
Description: Methyl 3-hydroxy-4-(hydroxymethyl)benzoate
UOM: 1 * 1 g
Image Unavailable-APOSPC9357-5G

1-(4-Fluorophenyl)-2-{[5-(hydroxymethyl)-1-methyl-1H-imidazol-2-yl]sulphanyl}-1-ethanone

Supplier: Apollo Scientific
Description: 1-(4-Fluorophenyl)-2-{[5-(hydroxymethyl)-1-methyl-1H-imidazol-2-yl]sulphanyl}-1-ethanone

Image Unavailable-APOSOR470854-1G

Methyl 3-(Hydroxymethyl)-5-nitrobenzoate

Catalog Number: (APOSOR470854-1G)
Supplier: Apollo Scientific
Description: Methyl 3-(Hydroxymethyl)-5-nitrobenzoate
UOM: 1 * 1 g
Image Unavailable-APOSOR917667-250MG

trans-Methyl 4-(hydroxymethyl)cyclohexanecarboxylate 95%

Supplier: Apollo Scientific
Description: trans-Methyl 4-(hydroxymethyl)cyclohexanecarboxylate 95%

Image Unavailable-APOSOR23333-100MG

5-(Hydroxymethyl)-4-methyl-2-phenylpyrimidine

Catalog Number: (APOSOR23333-100MG)
Supplier: Apollo Scientific
Description: 5-(Hydroxymethyl)-4-methyl-2-phenylpyrimidine
UOM: 1 * 100 mg
Image Unavailable-APOSOR902025-25G

Methyl-6-(hydroxymethyl)picolinate 95%

Supplier: Apollo Scientific
Description: Methyl-6-(hydroxymethyl)picolinate 95%

Image Unavailable-APOSOR55497-1G

(R)-4-Methyl-3-(hydroxymethyl)morpholine hydrochloride 95%

Catalog Number: (APOSOR55497-1G)
Supplier: Apollo Scientific
Description: (R)-4-Methyl-3-(hydroxymethyl)morpholine hydrochloride 95%
UOM: 1 * 1 g
Product Image-E170-500G

Tricine ≥99%, Ultrapure

Supplier: VWR Chemicals
Description: Biological buffers are useful for cell culture <i>in vitro</i>, enzyme assays and some electrophoretic applications at physiological pH.

SDS

Image Unavailable-APOSOR55070-5G

Methyl 2-(4-(hydroxymethyl)phenyl)acetate 95%

Supplier: Apollo Scientific
Description: Methyl 2-(4-(hydroxymethyl)phenyl)acetate 95%

Image Unavailable-APOSOR922936-10G

Methyl-2-(hydroxymethyl)acrylate 95%

Supplier: Apollo Scientific
Description: Methyl-2-(hydroxymethyl)acrylate 95%

Image Unavailable-APOSOR15967-1G

5-(Hydroxymethyl)-3-methylisoxazole

Supplier: Apollo Scientific
Description: 5-(Hydroxymethyl)-3-methylisoxazole

Image Unavailable-B22854.14

N-[Tris(hydroxymethyl)methyl]acrylamide 99%

Supplier: Thermo Fisher Scientific
Description: N-[Tris(hydroxymethyl)methyl]acrylamide 99%

SDS

Image Unavailable-APOSOR510049-250MG

Methyl 4-bromo-3-(hydroxymethyl)benzoate ≥95%

Catalog Number: (APOSOR510049-250MG)
Supplier: Apollo Scientific
Description: Methyl 4-bromo-3-(hydroxymethyl)benzoate ≥95%
UOM: 1 * 250 mg
Image Unavailable-J67272.MC

1,9-Pyrazoloanthrone 99%

Supplier: Thermo Fisher Scientific
Description: 1,9-Pyrazoloanthrone 99%

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