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You Searched For: 5-(Hydroxymethyl)-2-methyl-2H-indazole


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1-(1-Methyl-1H-indazol-3-yl)-1H-pyrrole-2,5-dione

Catalog Number: (APOSOR110108-1G)
Supplier: Apollo Scientific
Description: 1-(1-Methyl-1H-indazol-3-yl)-1H-pyrrole-2,5-dione
UOM: 1 * 1 g
Product Image-ACRO271052500

D-Glucono-1,5-lactone 99%

Supplier: Thermo Fisher Scientific
Description: D-Glucono-1,5-lactone 99%

SDS

Image Unavailable-APOSOR110171-250MG

4-Chloro-N-(1-methyl-1H-indazol-3-yl)butanamide

Supplier: Apollo Scientific
Description: 4-Chloro-N-(1-methyl-1H-indazol-3-yl)butanamide

Image Unavailable-APOSPC51024-500MG

6-Bromo-3-chloro-5-fluoro-1-methyl-1H-indazole

Supplier: Apollo Scientific
Description: 6-Bromo-3-chloro-5-fluoro-1-methyl-1H-indazole

Product Image-ACRO450740010

D-(+)-Glucose monohydrate 99+%, extra pure

Supplier: Thermo Fisher Scientific
Description: D-(+)-Glucose monohydrate 99+%, Extra Pure

SDS

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Anti-GUCY1A3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-13544R-A647)
Supplier: Bioss
Description: Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble forms, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor forms, known as GC, are peptide hormone receptors. GCS, a cGMP-synthesizing enzyme, is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one alpha subunit, designated GCS-alpha-1, and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both the alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13545R

Anti-GUCY1A2 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-13545R)
Supplier: Bioss
Description: Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
UOM: 1 * 100 µl
Image Unavailable-APOSOR7800T-100G

N-Acetyl-β-D-glucosamine 95%

Supplier: Apollo Scientific
Description: N-Acetyl-β-D-glucosamine 95%

Product Image-ACRO329911000

D-(+)-Maltose monohydrate 92+%

Supplier: Thermo Fisher Scientific
Description: D-(+)-Maltose monohydrate 92+%

SDS

Product Image-ACRO327241000

X-Gal (5-bromo-4-chloro-3-indolyl-ß-D-galactopyranoside) 99+% for molecular biology DNase-, RNase-, protease-free

Supplier: Thermo Fisher Scientific
Description: X-Gal (5-bromo-4-chloro-3-indolyl-ß-D-galactopyranoside) 99+% for molecular biology DNase-, RNase-, protease-free

SDS

Image Unavailable-APOSOR310757-1G

4-[(1-Oxo-7,8,9,10-tetrahydropyrazino[1,2-b]indazol-2(1H)-yl)methyl]benzoic acid

Catalog Number: (APOSOR310757-1G)
Supplier: Apollo Scientific
Description: 4-[(1-Oxo-7,8,9,10-tetrahydropyrazino[1,2-b]indazol-2(1H)-yl)methyl]benzoic acid
UOM: 1 * 1 g
Image Unavailable-APOSOR360108-250MG

1-N-BOC-3-methyl-indazole-5-boronic acid, pinacol ester 97%

Catalog Number: (APOSOR360108-250MG)
Supplier: Apollo Scientific
Description: 1-N-BOC-3-methyl-indazole-5-boronic acid, pinacol ester 97%
UOM: 1 * 250 mg
Product Image-ACRO303110050

(4-Nitrophenyl)-β-D-glucopyranoside 99%

Supplier: Thermo Fisher Scientific
Description: (4-Nitrophenyl)-β-D-glucopyranoside 99%

SDS

Image Unavailable-CAYM20797-500

Isomaltose ≥95%, crystalline solid

Supplier: Cayman Chemical
Description: Isomaltose is a glucose disaccharide with an α-(1 - 6) linkage, as opposed to the α-(1 - 4) linkage found in maltose. It can be liberated from dextran by dextranase and is hydrolyzed to D-glucose by isomaltase through an α-D-glucosidase-type action. Congenital sucrase-isomaltase deficiency is a rare autosomal intestinal disorder resulting from mutations affecting the gene encoding, the proprotein from which sucrase and isomaltase are produced.

Certificates

Image Unavailable-APOSBIMB8001-25G

IPTG (isopropyl-β-D-thiogalactopyranoside) ≥99% animal-, dioxane-free

Supplier: Apollo Scientific
Description: Material is synthesised from animal-free material.

Image Unavailable-ACTIAS12292G5

2,3-Dimethyl-6-nitro-1H-indazole

Catalog Number: (ACTIAS12292G5)
Supplier: ACTIVATE SCIENTIFIC
Description: 2,3-Dimethyl-6-nitro-1H-indazole
UOM: 1 * 5 g

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