Description: 1-Methyl-1H-indazole-6-boronic acid 97%

Catalog Number: ACRO430480010

UOM: 1 * 1 g

Supplier: Thermo Fisher Scientific

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Description: N-Octyl-β-D-glucopyranoside

Catalog Number: ENZOALX500001G001

UOM: 1 * 1 g

Supplier: ENZO LIFE SCIENCES

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Description: 4-[(1-Oxo-7,8,9,10-tetrahydropyrazino[1,2-b]indazol-2(1H)-yl)methyl]benzoic acid

Catalog Number: APOSOR310757-1G

UOM: 1 * 1 g

Supplier: Apollo Scientific

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Description: 6-Fluoro-3-iodo-1-methyl-1H-indazole 95%

Catalog Number: APOSPC7949-250MG

UOM: 1 * 250 mg

Supplier: Apollo Scientific

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Description: Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble forms, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor forms, known as GC, are peptide hormone receptors. GCS, a cGMP-synthesizing enzyme, is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one alpha subunit, designated GCS-alpha-1, and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both the alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity.

Catalog Number: BOSSBS-13544R-HRP

UOM: 1 * 100 µl

Supplier: Bioss

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Description: X-Gal (5-bromo-4-chloro-3-indolyl-ß-D-galactopyranoside)

Catalog Number: ROCKXGAL-0100

UOM: 1 * 100 mg

Supplier: Rockland Immunochemicals

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Description: X-Gal (5-bromo-4-chloro-3-indolyl-ß-D-galactopyranoside)

Catalog Number: A1007.0001

UOM: 1 * 1 g

Supplier: PanReac AppliChem

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Description: D-Glucono-1,5-lactone ≥99%

Catalog Number: A13105.30

UOM: 1 * 250 g

Supplier: Thermo Fisher Scientific

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Description: 4-Iodo-N-(1-methyl-1H-indazol-3-yl)benzenesulphonamide

Catalog Number: APOSOR111297-1G

UOM: 1 * 1 g

Supplier: Apollo Scientific

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Description: 1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylic acid

Catalog Number: APOSPC200018-500MG

UOM: 1 * 500 mg

Supplier: Apollo Scientific

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Description: D-(+)-Maltose monohydrate

Catalog Number: APOSBIK9000-1KG

UOM: 1 * 1 kg

Supplier: Apollo Scientific

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Description: D-(+)-Glucose monohydrate for microbiology pH 6 - 7 (100 g/l, H₂O, 20 °C), Millipore®

Catalog Number: 1.08342.9025

UOM: 1 * 25 kg

Supplier: Merck

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Description: 2,3-Dimethyl-6-nitro-1H-indazole

Catalog Number: ACTIAS12292G5

UOM: 1 * 5 g

Supplier: ACTIVATE SCIENTIFIC

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Description: An aminoglycoside antibiotic with bactericidal activity

Catalog Number: APOSBIA0164-25G

UOM: 1 * 25 g

Supplier: Apollo Scientific

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Description: 4-Chloro-N-(1-methyl-1H-indazol-3-yl)butanamide

Catalog Number: APOSOR110171-250MG

UOM: 1 * 250 mg

Supplier: Apollo Scientific

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Description: 6-Bromo-3-chloro-5-fluoro-1-methyl-1H-indazole

Catalog Number: APOSPC51024-500MG

UOM: 1 * 500 mg

Supplier: Apollo Scientific

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