all-rac-α-Tocopherol 96.0-102.0%, EMPROVE® ESSENTIAL Ph. Eur., BP, USP, E307, SAFC®

Supplier: MERCK PRODUCTION CHEMICALS
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Synonyms: DL-alpha-TocopherolVitamin Eall-rac-α-TocopherolVitamin E Alcohol(±)-α-Tocopherol3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol

5.00949.5000EA 1870 GBP
5.00949.5000 5.00949.9020
all-rac-α-Tocopherol 96.0-102.0%, EMPROVE® ESSENTIAL Ph. Eur., BP, USP, E307, SAFC®
DL-α-Tocopherol

Corresponds to Ph. Eur., BP, USP, E 307
Conforms to the purity criteria on food additives according to the current European Commission Regulation.
# specified acc. to EMEA/CHMP/SWP/4446/2000 (Specification limits for residues of metal catalysts or metal reagents).
Other residues of metal catalysts or metal reagents acc. to this guideline are not likely to be present.

Formula: C₂₉H₅₀O₂
MW: 430.71 g/mol
Storage Temperature: Ambient
MDL Number: MFCD00072051
CAS Number: 10191-41-0
EINECS: 233-466-0

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Specification Test Results

Assay (GC, Ph. Eur.) 96.0 - 102.0 %
Assay (GC, USP) 96.0 - 102.0 %
Identity (IR) conforms
Identity (GC) conforms
Identity (colour reaction) conforms
Appearance clear, colourless to yellow-brownish, viscous, oily liquid; almost odourless
Acidity conforms
Optical rotation α 20/D (100 g/l; anhydrous ethanol) -0.01 - 0.01 °
Optical rotation α 25/D (100 g/l; chloroforme) -0.05 - 0.05 °
Refractive index (n 20/D) 1.503 - 1.507
Spec. Absorptivity A 1%/1cm (292 nm; 0,1 g/l, anhydrous ethanol) 72 - 76
Spec. Absorptivity A1%/1cm (292 nm; 0,05 g/l , anhydrous Ethanol) 71 - 76
Heavy metals (as Pb) ≤ 10 ppm
As (Arsenic) ≤ 3 ppm
Cu (Copper) ≤ 10 ppm
Hg (Mercury) ≤ 1 ppm
Pb (Lead) ≤ 2 ppm
Zn (Zinc)# ≤ 25 ppm
Heptane (HS-GC) ≤ 5000 ppm
Methanol (HS-GC) ≤ 3000 ppm
Pyridine (HS-GC) ≤ 200 ppm
Toluene (HS-GC) ≤ 890 ppm
Other residual solvents (ICH Q3C) excluded by manucfacturing process
Related substances (Ph. Eur., impurity A) ≤ 0.5 %
Related substances (Ph. Eur., impurity B) ≤ 1.5 %
Related substances (Ph. Eur., sum of impurities C and D) ≤ 1.0 %
Related substances (Ph. Eur., any other impurity) ≤ 0.25 %
Related substances (Ph. Eur., total impurities) ≤ 2.5 %
Sulfated ash (600 °C) ≤ 0.1 %

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