Invasion chambers, Corning® BioCoat™ Matrigel®

Supplier: Corning
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354483 354481 354480
734-1049EA 607 GBP
734-1049 734-1048 734-1047
Invasion chambers, Corning® BioCoat™ Matrigel®
Cell Culture Supplements and Additives

An in vitro system for assessing the invasive potential of both malignant and normal cells.


  • Proven biological performance using Corning® FluoroBlok™ PET membrane coated with Corning® Matrigel® matrix
  • Allows for rapid and reproducible quantitation of tumour cell invasion in vitro
  • Increase throughput for tumour cell invasion assays
  • Allows automation of assays with simplified and non-destructive fluorescence detection
  • Saves time and labour screening for prospective anti-metastatic compounds


Corning® BioCoat™ Matrigel® invasion chambers enable studies of metastatic potential of tumour cells; expression of matrix metalloproteinase on the surface of invasive tumour cells; inhibition of metastasis by ECM components or antineoplastic drugs (i.e. Taxol®); altered expression of cell surface proteins in metastatic cells; and invasion of normal cells, such as embryonic stem cells, cytotrophoblasts, and fibroblasts as well as of multiple cell lines. The Corning® BioCoat™ Matrigel® invasion chamber is an in vitro system for the study of cell invasion through the basement membrane. It consists of Falcon® cell culture inserts containing an 8,0 µm pore-size PET membrane coated with a uniform layer of Corning® Matrigel® matrix.


The Corning® BioCoat™ tumour invasion system is an in vitro system for the study of tumour cell invasion through the basement membrane. It consists of Corning® FluoroBlok™ multiwell insert plates containing an 8,0 µm pore size Corning® FluoroBlok™ membrane coated with a uniform layer of Corning® Matrigel® basement membrane matrix. The Corning® Matrigel® matrix occludes the pores of the Corning® FluoroBlok™ membrane, blocking non-invasive cells from migrating through the membrane.

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SPECIFICATIONS

Environmentally Preferable Low Manufacturing Impact Low Manufacturing Impact Low Manufacturing Impact
Species
Quality control Tested for the ability to allow invasion of HT-1080 cells, an invasive human fibrosarcoma cell line, and to exclude invasion of 3T3 cells, a non-invasive mouse fibroblast cell line
Tested and found negative for bacteria and fungi
Tested for the ability to allow invasion of HT-1080 cells, an invasive human fibrosarcoma cell line, and to exclude invasion of 3T3 cells, a non-invasive mouse fibroblast cell line
Tested and found negative for bacteria and fungi
Tested for the ability to allow invasion of HT-1080 cells, an invasive human fibrosarcoma cell line, and to exclude invasion of 3T3 cells, a non-invasive mouse fibroblast cell line
Tested and found negative for bacteria and fungi
Source
Storage and stability Store at −20 °C in original packaging. Stable for at least 3 months at −20 °C Store at −20 °C in original packaging. Stable for at least 3 months at −20 °C Store at −20 °C in original packaging. Stable for at least 3 months at −20 °C
Environmental certification ISO 14001 - Bedford ISO 14001 - Bedford ISO 14001 - Bedford

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